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Super-TDU TFA - ≥98% , CAS No.1599441-71-0(free base)
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Targets
YAP/TEAD interaction
In vitro
Super-TDU reduced endogenous interaction between YAP and TEADs. It inhibits cell viability and colony formation of GC cell lines MGC-803, BGC-823, and HGC27, but not MKN-45. Moreover, the Super-TDU downregulated expression of YAP-TEADs target genes CTGF, CYR61, and CDX2. Super-TDU significantly inhibited growth of HeLa, MGC-803, HCT116, A549, and MCF-7 cells, but only marginally inhibited growth of Jurkat and Raji cells, indicating a selectivity of the Super-TDU in inhibiting tumor cell growth. Super-TDU may specifically target tumor cells with an elevated YAP/VGLL4 ratio.
In vivo
Super-TDU has the potential in treating gastric cancer by directly targeting YAP-TEADs, and importantly, unlike the conventional drug compound 5-FU, its antitumor activity tends to be specific toward tumors with an elevated ratio of YAP to VGLL4.
Cell Research(from reference)
Cell lines：HCT116 and SW480 cells
Concentrations：0-320 ng/ml
Incubation Time：72 h
Specifications
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Super-TDU is an inhibitory peptide targeting YAP-TEADs interaction.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
| Molecular Weight | 5280.92(free base) |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2429241 | Certificate of Analysis | Feb 21, 2024 | S414053 |
| C2429242 | Certificate of Analysis | Feb 21, 2024 | S414053 |
| C2429243 | Certificate of Analysis | Feb 21, 2024 | S414053 |
| C2429244 | Certificate of Analysis | Feb 21, 2024 | S414053 |
| C2429245 | Certificate of Analysis | Feb 21, 2024 | S414053 |
| C2429246 | Certificate of Analysis | Feb 21, 2024 | S414053 |
Chemical and Physical Properties
| Solubility | Solubility (25°C) In vitro Water: 100 mg/mL (18.93 mM); |
|---|---|
| Sensitivity | Moisture Sensitive |
Solution Calculators
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