Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor

Name: Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor
SKU: S650066
Availability: InStock

CAS: 168828-58-8 Cat. No.: S650066 Summenformel: C₁₆H₂₀FN₃O₃S Molekulargewicht: 353.41 EG-Nummer: 809-216-7 PubChem CID: 465951

COA

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Sutezolid - ≥99% CAS No(168828-58-8) by Aladdin Scientific

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GRADE & PURITY ≥99%

Synonyms

NH-125; NH 125;eEF-2 Kinase Inhibitor, NH125 | SUTEZOLID [WHO-DD] | Sutezolid (USAN/INN) | U-480 | Oxazolidininone | DTXSID20168611 | HY-10251 | AS-74370 | 9EN | cis-3-(Benzyloxymethyl)cyclobutanol, 97% | HY-10392 | N-{[(5S)-3-[3-FLUORO-4-(THIOMORPHOLIN-4

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht Specifications Produkteigenschaften Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen

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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

In Vivo

Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Oxazolidinone

Specifications

Synonyme

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

Sutezolid (PNU-100480), an active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis . Sutezolid has potent activity against mycobacteria , and is used for the research of drug-resistant tuberculosis.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Mechanismus der Wirkung

70S ribosome inhibitor

Reinheit

≥99%

Produkteigenschaften

ALogP

1.5

Namen und Kennungen

Pubchem Sid

528767317

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528767317

Kanonisches Lächeln

CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F

IUPAC Name

N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

InChIKey

FNDDDNOJWPQCBZ-ZDUSSCGKSA-N

INCHI

1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

Isomere SMILES

CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F

PubChem CID

465951

Molekulargewicht

353.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Klasse Thiazinanes
    - Subclass Thiomorpholines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Klasse	Thiazinanes
Subclass	Thiomorpholines
Intermediate Tree Nodes	Not available
Direct Parent	Phenylthiomorpholines
Alternative Parents	Aniline and substituted anilines Dialkylarylamines Fluorobenzenes Oxazolidinones Aryl fluorides Acetamides Carbamate esters Secondary carboxylic acid amides Organic carbonic acids and derivatives Dialkylthioethers Azacyclic compounds Oxacyclic compounds Hydrocarbon derivatives Organofluorides Organopnictogen compounds Carbonyl compounds Organic oxides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	4-phenylthiomorpholine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Oxazolidinone - Acetamide - Carbamic acid ester - Oxazolidine - Carboxamide group - Amino acid or derivatives - Tertiary amine - Carbonic acid derivative - Secondary carboxylic acid amide - Oxacycle - Azacycle - Dialkylthioether - Carboxylic acid derivative - Thioether - Organic oxygen compound - Organic oxide - Amine - Hydrocarbon derivative - Carbonyl group - Organopnictogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as phenylthiomorpholines. These are compounds containing a thiomorpholine ring conjugated to a phenyl group. Thiomorpholine a six-membered aliphatic ring containing one nitrogen atom and one sulfur atom at positions 1 and 4 respectively, and four carbon atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

MAOB Tclin Amine oxidase [flavin-containing] B (1 Activities)

Discover Target: MAOB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MT4 (17854 Activities)

Lot Number	Certificate Type	Datum	Artikel
I2411275	Certificate of Analysis	Jul 26, 2024	S650066
I2411276	Certificate of Analysis	Jul 26, 2024	S650066
I2411277	Certificate of Analysis	Jul 26, 2024	S650066
I2411278	Certificate of Analysis	Jul 26, 2024	S650066
I2411279	Certificate of Analysis	Jul 26, 2024	S650066
I2411280	Certificate of Analysis	Jul 26, 2024	S650066
I2411281	Certificate of Analysis	Jul 26, 2024	S650066
I2411282	Certificate of Analysis	Jul 26, 2024	S650066
I2411283	Certificate of Analysis	Jul 26, 2024	S650066
I2411284	Certificate of Analysis	Jul 26, 2024	S650066

Löslichkeit	DMSO : 50 mg/mL (141.48 mM; Need ultrasonic)
Molekulargewicht	353.400 g/mol
XLogP3	1.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	353.121 Da
Monoisotopic Mass	353.121 Da
Topological Polar Surface Area	87.200 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	475.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor

Storage & shipping

Quality documents

Literature proof

Übersicht

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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