| 1. Jiaqi Zhang, Haole Qi, Mingxia Wang, Yongqin Wei, Hao Liang. (2023) Enzymatically hydrolyzed sodium caseinate nanoparticles efficiently enhancing the solubility, stability, and antioxidant and anti-biofilm activities of hydrophobic Tanshinone IIA. Journal of Materials Chemistry B, 11 (11): (2440-2454). [PMID:36810656] [10.1039/D2TB02263J] |
| 2. Ling Yu, Yubin Liang, Lei Gao, Peipei Chen, Zhiqiang Yu, Minzhou Zhang, Aleksander Hinek, Shuai Mao. (2022) Reconstruction of Postinfarcted Cardiac Functions Through Injection of Tanshinone IIA@ Reactive Oxygen Species-Sensitive Microspheres Encapsulated in a Thermoreversible Hydrogel. Energy & Environmental Materials, [PMID:] [10.1002/eem2.12555] |
| 3. Yingru Zhang, Yiyang Zhao, Jingwen Liu, Chunpu Li, Ying Feng, Shasha Jiang, Xiaoting Sun, Xueqing Hu, Yan Wang. (2022) Transgelin-2 Involves in the Apoptosis of Colorectal Cancer Cells Induced by Tanshinone-IIA. Analytical Cellular Pathology, [PMID:36204303] [10.1155/2022/9358583] |
| 4. Min Shi, Ruiyan Zhu, Yi Zhang, Siwei Zhang, Tingyao Liu, Kunlun Li, Shucan Liu, Leran Wang, Yao Wang, Wei Zhou, Qiang Hua, Guoyin Kai. (2022) A novel WRKY34-bZIP3 module regulates phenolic acid and tanshinone biosynthesis in Salvia miltiorrhiza. METABOLIC ENGINEERING, [PMID:35934177] [10.1016/j.ymben.2022.08.002] |
| 5. Shen Qing, Wang Haixing, Quan Bin, Sun Xiuhua, Wu Guohua, Huang Darong, Wang Qingcheng, Luo Pei. (2022) Rapid quantification of bioactive compounds in Salvia miltiorrhiza Bunge derived decoction pieces, dripping pill, injection, and tablets by polarity-switching UPLC-MS/MS. Frontiers in Chemistry, [PMID:35910733] [10.3389/fchem.2022.964744] |
| 6. Meixuan Liu, Sha Liu, Xiaosu Zhu, Yiying Sun, Linyu Su, Hairong Yu, Deshuai Liu, Ying Li, Yuan Du, Rongxia Liu, Kaoxiang Sun. (2022) Tanshinone IIA-Loaded Micelles Functionalized with Rosmarinic Acid: A Novel Synergistic Anti-Inflammatory Strategy for Treatment of Atherosclerosis. JOURNAL OF PHARMACEUTICAL SCIENCES, [PMID:35580692] [10.1016/j.xphs.2022.05.007] |
| 7. Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen. (2020) Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling. Annals of Hepatology, [PMID:32980439] [10.1016/j.aohep.2020.07.013] |
| 8. Xiaolong Hao, Zhongqiang Pu, Gang Cao, Dawei You, Yang Zhou, Changping Deng, Min Shi, Shivraj Hariram Nile, Yao Wang, Wei Zhou, Guoyin Kai. (2020) Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots. Journal of Advanced Research, [PMID:32071787] [10.1016/j.jare.2020.01.012] |
| 9. Changping Deng, Xiaolong Hao, Min Shi, Rong Fu, Yao Wang, Yi Zhang, Wei Zhou, Yue Feng, Nokwanda P. Makunga, Guoyin Kai. (2019) Tanshinone production could be increased by the expression of SmWRKY2 in Salvia miltiorrhiza hairy roots. PLANT SCIENCE, [PMID:31084862] [10.1016/j.plantsci.2019.03.007] |
| 10. Jian Fang, Qiuyan Chen, Baozhu He, Jiaxuan Cai, Yawen Yao, Yi Cai, Suowen Xu, Kannan R.R. Rengasamy, Shanmugaraj Gowrishankar, Shunmugiah Karutha Pandian, Tiansheng Cao. (2018) Tanshinone IIA attenuates TNF-α induced PTX3 expression and monocyte adhesion to endothelial cells through the p38/NF-κB pathway. FOOD AND CHEMICAL TOXICOLOGY, [PMID:30268796] [10.1016/j.fct.2018.09.063] |
| 11. Zhu Yingchun, Tang Qiqiang, Wang Guopin, Han Ruodong. (2017) Tanshinone IIA Protects Hippocampal Neuronal Cells from Reactive Oxygen Species Through Changes in Autophagy and Activation of Phosphatidylinositol 3-Kinase, Protein Kinas B, and Mechanistic Target of Rapamycin Pathways. CURRENT NEUROVASCULAR RESEARCH, 14 (2): (132-140). [PMID:28260507] [10.2174/1567202614666170306105315] |
| 12. Xu-Xin Zhang, Yun-Feng Cao, Li-Xuan Wang, Xiao-Lin Yuan, Zhong-Ze Fang. (2017) Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs). PHARMACEUTICAL BIOLOGY, [PMID:28466663] [10.3109/13880209.2015.1045621] |
| 13. Man Wang, Wentao Bi, Xiaohua Huang, David Da Yong Chen. (2016) Ball mill assisted rapid mechanochemical extraction method for natural products from plants. JOURNAL OF CHROMATOGRAPHY A, [PMID:27157426] [10.1016/j.chroma.2016.04.044] |
| 14. Shi Min, Zhou Wei, Zhang Jianlin, Huang Shengxiong, Wang Huizhong, Kai Guoyin. (2016) Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins. Scientific Reports, 6 (1): (1-11). [PMID:26875847] [10.1038/srep20919] |
| 15. Min Shi, Xiuqin Luo, Guanhua Ju, Leilei Li, Shengxiong Huang, Tong Zhang, Huizhong Wang, Guoyin Kai. (2016) Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:26753746] [10.1021/acs.jafc.5b04697] |
| 16. Chen Minggang, Liu Yumei, Yi Dan, Wei Liuping, Li Yumei, Zhang Li. (2014) Tanshinone IIA Promotes Pulmonary Artery Smooth Muscle Cell Apoptosis in Vitro by Inhibiting the JAK2/STAT3 Signaling Pathway. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 33 (4): (1130-1138). [PMID:24733040] [10.1159/000358682] |
| 17. Gao Jiaming, Guo Hao, Li Junmei, Zhan Min, You Yue, Xin Gaojie, Liu Zixin, Fan Xiaodi, Gao Qinghe, Liu Jianxun, Zhang Yehao, Fu Jianhua. (2024) Buyang Huanwu decoction ameliorates myocardial injury and attenuates platelet activation by regulating the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway. Chinese Medicine, 19 (1): (1-17). [PMID:39160598] [10.1186/s13020-024-00976-0] |
| 18. Ya-Long Zheng, Yuan Ji, Yan Li, Shuai Yan, Xiao-Rong Ren, Wei Tang, Fang Dai, Bo Zhou. (2024) Identification of tanshinone I as a natural Cu(II) ionophore. FREE RADICAL BIOLOGY AND MEDICINE, [PMID:39613045] [10.1016/j.freeradbiomed.2024.11.049] |
| 19. Yong Jiang, Wenjun Ji, Ying Lu, Qin Wang, Linwei Chen. (2025) Integrating Plasma Metabolomics, Network Pharmacology, and Experimental Validation to Investigate the Action Mechanism of Qiangxin Lishui Prescription in Chronic Heart Failure. BIOMEDICAL CHROMATOGRAPHY, 39 (2): (e6065). [PMID:39748248] [10.1002/bmc.6065] |
| 20. Jinfu Wang, Yan Guo, Huifen Zhou, Yanjie Hua, Haitong Wan, Jiehong Yang. (2024) Investigating the Mechanistic of Danhong Injection in Brain Damage Caused by Cardiac I/R Injury via Bioinformatics, Computer Simulation, and Experimental Validation. ACS Omega, [PMID:38680343] [10.1021/acsomega.4c00200] |
| 21. Jinghui Li, Yan Kang, Ying Wang, Jiaxin Liu, Yingting Wang, Sitong Liu, Yunxi Bu, Xiangqun Li, Jiahan Xie, Zhibing Wang. (2025) Ionic Liquid-Based Polarity-Adjustable Deep Eutectic Solvent Extraction Followed by High-Performance Liquid Chromatography-Diode-Array Detection for the Determination of Liposoluble Anthraquinones in Salvia miltiorrhiza Bge. Root. JOURNAL OF SEPARATION SCIENCE, 48 (3): (e70116). [PMID:40057467] [10.1002/jssc.70116] |
| 22. Shaoping Ma, Changyong Cai, Xuhong Guo, Zhijian Tan. (2025) Selective separation of tanshinone homologs by biocomposite membranes based on poly(ionic liquids) and natural fibers. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39793843] [10.1016/j.ijbiomac.2025.139568] |
| 23. Dong Han, Yun-Biao Chen, Kai Zhao, Hong-Zhou Li, Xing-Yu Chen, Guo-Zheng Zhu, Chen Tu, Jia-Wen Gao, Jing-Shen Zhuang, Zhi-Yong Wu, Zhao-Ming Zhong. (2024) Tanshinone IIA alleviates inflammation-induced skeletal muscle atrophy by regulating mitochondrial dysfunction. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, [PMID:39547552] [10.1016/j.abb.2024.110215] |
| 24. Dajin Pi, Zheng Liang, Jinyue Pan, Jianwei Zhen, Chuiyang Zheng, Wen Fan, Qingliang Song, Maoxing Pan, Qinhe Yang, Yupei Zhang. (2024) Tanshinone IIA Inhibits the Endoplasmic Reticulum Stress-Induced Unfolded Protein Response by Activating the PPARα/FGF21 Axis to Ameliorate Nonalcoholic Steatohepatitis. Antioxidants, 13 (9): (1026). [PMID:39334685] [10.3390/antiox13091026] |
| 25. Wenyu Chen, Yuanyuan Gao, Yuanqi Liu, Yujia Luo, Xinrui Xue, Chujie Xiao, Kun Wei. (2024) Tanshinone IIA Loaded Inhaled Polymer Nanoparticles Alleviate Established Pulmonary Fibrosis. ACS Biomaterials Science & Engineering, [PMID:39288315] [10.1021/acsbiomaterials.4c00532] |
| 26. Hui Gao, Shan Li, Zhengyuan Ding, Yaqiu Zhou, Yi Yao, Mengwei Li, Mengjie Su, Zengqiang Wu, Chunmei Yu. (2025) 3D stretchable and conductive scaffold for the in situ cell culture and real time profiling of extracellular H2S. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2025.138435] |
| 27. Shuai Mao, Yubin Liang, Zikang Chen, Lei Wang, Quanfu Chen, Zhuting Fang, Qifan Zheng, Wen Ma, Hanping Zhang, Zhiqiang Yu, Ling Yu. (2025) Adaptive bioactivable nanosystems for synergistic myocardial infarction therapy using traditional pharmaceutics. Bioactive Materials, [PMID:40988940] [10.1016/j.bioactmat.2025.08.041] |
| 28. Dong Hua, Tang Guannan, Ma Ting, Cao Xiaodong. (2015) One-step fabrication of inorganic/organic hybrid microspheres with tunable surface texture for controlled drug release application. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 27 (1): (1-8). [PMID:26610930] [10.1007/s10856-015-5624-y] |
| 29. Chong Zhong, Yong-Fa Zhang, Jun-Hai Huang, Zi-Yu Wang, Qiu-Yuan Chen, Li-Tian Su, Zhen-Tao Liu, Cheng-Ming Xiong, Zhi Tao, Rong-Ping Guo. (2017) The Chinese medicine, Jianpi Huayu Decoction, inhibits the epithelial mesenchymal transition via the regulation of the Smad3/Smad7 cascade. American Journal of Translational Research, [PMID:28670362] [PMID:28670362] |
| 30. Ling Yu, Yubin Liang, Jialin Lai, Lei Wang, Wei Wang, Quanfu Chen, Liheng Guo, Minzhou Zhang, Zhiqiang Yu, Shuai Mao. (2025) Injectable nitric oxide-generated hydrogel delivering tanshinone IIA for cardiac remodeling in zebrafish and porcine models. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.165249] |
| 31. Ying Jiang, Xinjie Wang, Zhenyang Wang, Shengliang Zhang, Jianhua Wang, Xianglong Wang, Yang Zhang. (2025) Tanshinone IIA Restrains Hepatocellular Carcinoma Progression by Regulating METTL3-Mediated m6A Modification of TRIB3 mRNA. Turkish Journal of Gastroenterology, 36 (7): (431). [PMID:39910904] [10.5152/tjg.2025.24304] |
| 32. Li Hao, Ju Shuguang, Wang Jiacheng, Kuang Donglin, Chen Pengfei, Zhang Mengfan, Qian Ruijie, Liang Chao, Han Daqian, Duan Xuhua. (2025) Tanshinone IIA inhibits heat-induced growth of p53-mutant Huh-7 hepatocellular carcinoma by modulating osmotic homeostasis and glycolysis through targeting ALDH7A1. Cell Death Discovery, 11 (1): (1-20). [PMID:41173836] [10.1038/s41420-025-02795-0] |
| 33. Haiyun Zhang, Xiujuan Wang, Yilun Wang, Yuanyuan Zhao, Yibing Chen, Yuanlu Cui, Qiangsong Wang. (2025) Tanshinone IIA and quercetin loaded nanoemulsion-thermogel composite system for enhanced acne management: In-vitro/ in-vivo evaluation. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2025.107918] |
| 34. Shu Zhang, Xin Dong, Gangyi Chen, Chao Wang. (2025) Tanshinone IIA alleviates LPS-induced acute kidney injury by inhibiting RIP3/Nrf2-mediated oxidative stress. RENAL FAILURE, [PMID:41346077] [10.1080/0886022X.2025.2593719] |
| 35. Ting Pan, Xianwei Zhu, Ying Sui, Zhixin Zhang, Yongtao Su. (2025) Tanshinone IIA Accelerates Diabetic Wound Healing via Suppression of Macrophage NLRP3 Inflammasome Activity. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, [PMID:41435748] [10.1016/j.bbrc.2025.153171] |
| 36. Huaan Li, Letian Cao, Suling Huang, Peiwen Deng, Lifang Guo, Dingsheng Wen, Lu Wen, Gang Chen. (2025) A fast-slow liposome based “orthodox-unexpected interplay” strategy for bacterial otitis media and associated hearing loss. JOURNAL OF CONTROLLED RELEASE, [PMID:41456803] [10.1016/j.jconrel.2025.114579] |
| 37. Chenrui Zhang, Yongqin He, Xuejiao Wei, Shuanglong Mou, Mengsha Li, Xingwei Hu, Bing Li. (2025) Network Pharmacology and Experimental Validation to Identify Potential Key Compounds of Danhong Injection in the Treatment of Myocardial Infarction. Chemical Biology & Drug Design, 106 (6): (e70223). [PMID:41432248] [10.1111/cbdd.70223] |
| 38. Fei An, Huiling Gao, Lin Tang, Yaqian Li, Xiaoyu Li, Tongyao Yuan, Yun Mo, Hao Liang, Jianzhang Liu. (2026) A Tanshinone IIA-Loaded Nanorod Coating on Titanium Abutments for Antibacterial and Antibiofilm Activity. Advanced Healthcare Materials, [PMID:41738706] [10.1002/adhm.202504686] |
| 39. Xinyu Li, Xiaoyang Zhou, Zhiyong Li, Zilu Zhu, Songtao Wang, Jiaolong Huang, Kai Lian, Peng Duan, Chunhui Hu, Yihua Shi. (2026) Therapeutic functions of tanshinone IIA in a zebrafish model of glucocorticoid-induced osteoporosis. Frontiers in Pharmacology, [PMID:41929250] [10.3389/fphar.2026.1772925] |
