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| Beschreibung | Serine/threonine-protein kinase Nek4 |
|---|
Gene and Protein Information
| Gene ID | 6787 |
|---|---|
| Uniprot Accession IDs | P51957 A5YM70 B2R633 B7Z200 Q6P576 |
| Ensembl ID | ENSP00000233027 |
| Symbol | STK2 NRK2 STK2 pp12301 |
| Family | Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. |
| Sequence | MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLGSSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMNF Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Steuer-ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 695646 | NEK4 | NIMA related kinase 4 | 9544 | OMA, EggNOG | |
| Mouse | 23955 | Nek4 | NIMA (never in mitosis gene a)-related expressed kinase 4 | 10090 | MGI:1344404 | Inparanoid, OMA, EggNOG |
| Rat | 306252 | Nek4 | NIMA-related kinase 4 | 10116 | RGD:1304995 | Inparanoid, EggNOG |
| Dog | 476591 | NEK4 | NIMA related kinase 4 | 9615 | VGNC:43732 | Inparanoid, OMA, EggNOG |
| Horse | 100051545 | NEK4 | NIMA related kinase 4 | 9796 | VGNC:20671 | Inparanoid, OMA, EggNOG |
| Cow | 511455 | NEK4 | NIMA related kinase 4 | 9913 | VGNC:31995 | Inparanoid, OMA, EggNOG |
| Pig | 106504146 | NEK4 | NIMA related kinase 4 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100020318 | NEK4 | NIMA related kinase 4 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | NEK4 | NIMA related kinase 4 [Source:HGNC Symbol;Acc:HGNC:11399] | 9258 | OMA, EggNOG | ||
| Anole lizard | 100560174 | nek4 | NIMA related kinase 4 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 780225 | nek4 | NIMA-related kinase 4 | 8364 | XB-GENE-5914376 | Inparanoid, OMA, EggNOG |
| Zebrafish | 393987 | nek4 | NIMA-related kinase 4 | 7955 | ZDB-GENE-040426-1392 | Inparanoid, OMA, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / Other group / NEK family / Serine/threonine-protein kinase nek4
protein / Kinase / Protein kinase / Other group / NEK family / Serine/threonine-protein kinase nek4
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Verfügbarkeit | Details anzeigen |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Anwendung | Verfügbarkeit | Details anzeigen |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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