🌎 Ship to: United States
Navigation umschalten
Cart
Search
Versand am selben Tag für alle vorrätigen Artikel.
Erweiterte Suche
Schnelle Bestellung SDS / CoA Structure Großmengen & Sonderanfragen
Menü
Konto
Einstellungen
྾
224,000+ Forschungsprodukte · Triple ISO certified · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag auf Lager

DOT1L

BeschreibungHistone-lysine N-methyltransferase, H3 lysine-79 specific

Gene and Protein Information

Gene ID84444
Uniprot Accession IDs Q8TEK3 O60379 Q96JL1
Ensembl ID ENSP00000381657
Symbol KIAA1814 KMT4 DOT1 KMT4
FamilyBelongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
Sequence
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameSteuer-IDOther Gene IDSources
Chimp455566DOT1LDOT1 like histone lysine methyltransferase9598VGNC:7478OMA, EggNOG
Macaque710033DOT1LDOT1 like histone lysine methyltransferase9544Inparanoid, OMA, EggNOG
Mouse208266Dot1lDOT1-like, histone H3 methyltransferase (S. cerevisiae)10090MGI:2143886Inparanoid, OMA, EggNOG
Rat362831Dot1lDOT1 like histone lysine methyltransferase10116RGD:1306644Inparanoid, OMA, EggNOG
Dog485073DOT1LDOT1 like histone lysine methyltransferase9615VGNC:54298Inparanoid, OMA, EggNOG
Horse100068506DOT1LDOT1 like histone lysine methyltransferase9796VGNC:50588Inparanoid, OMA, EggNOG
Cow510442DOT1LDOT1 like histone lysine methyltransferase9913VGNC:50607OMA, EggNOG
Pig100738665DOT1LDOT1 like histone lysine methyltransferase9823OMA, EggNOG
Opossum100619840DOT1LDOT1 like histone lysine methyltransferase13616Inparanoid, OMA, EggNOG
Chicken420078DOT1LDOT1 like histone lysine methyltransferase9031CGNC:549OMA, EggNOG
Xenopusdot1lDOT1-like histone H3K79 methyltransferase [Source:Xenbase;Acc:XB-GENE-6033925]8364OMA, EggNOG
Zebrafish559945dot1lDOT1-like histone H3K79 methyltransferase7955ZDB-GENE-060503-341Inparanoid, OMA, EggNOG
Fruitfly40793gppgrappa7227FBgn0264495Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    transferase    /    methyltransferase    /    Histone-lysine N-methyltransferase, H3 lysine-79 specific
DTO Classes
protein    /    Epigenetic regulator    /    Writer    /    Protein methyltransferase    /    Histone-lysine N-methyltransferase, H3 lysine-79 specific

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelVerfügbarkeitDetails anzeigen

Associated Antibodies

NameSpecificationsSpecies reactivityAnwendungVerfügbarkeitDetails anzeigen

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
      Wir verwenden Cookies, um die ordnungsgemäße Funktion der Website sicherzustellen und, soweit zulässig, Ihr Nutzererlebnis zu verbessern. Sie können Ihre Einstellungen jederzeit unter „Einstellungen“ verwalten. Weitere Informationen finden Sie in unserer Cookie-Richtlinie.

      Shall we send you a message when we have discounts available?

      Remind me later

      Thank you! Please check your email inbox to confirm.

      Oops! Notifications are disabled.

      Privacy Policy Terms of Use Cookie Policy Terms and Conditions of Sale Sales Policy
      Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
      Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.