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OPA1

BeschreibungDynamin-like 120 kDa protein, mitochondrial

Gene and Protein Information

Gene ID4976
Uniprot Accession IDs O60313 D3DNW4 E5KLJ5 E5KLJ6 E5KLJ7 E5KLK1 E5KLK2
Ensembl ID ENSP00000354681
Symbol KIAA0567 NPG NTG MGM1 BERHS largeG MTDPS14
FamilyBelongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Sequence
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameSteuer-IDOther Gene IDSources
Chimp471042OPA1OPA1, mitochondrial dynamin like GTPase9598VGNC:8843OMA, EggNOG
Macaque698540OPA1OPA1, mitochondrial dynamin like GTPase9544Inparanoid, OMA, EggNOG
Mouse74143Opa1OPA1, mitochondrial dynamin like GTPase10090MGI:1921393Inparanoid, OMA, EggNOG
Rat171116Opa1OPA1, mitochondrial dynamin like GTPase10116RGD:708423Inparanoid, OMA
Horse100059993OPA1OPA1, mitochondrial dynamin like GTPase9796VGNC:21035Inparanoid, OMA, EggNOG
Cow524142OPA1OPA1, mitochondrial dynamin like GTPase9913VGNC:32432Inparanoid, OMA, EggNOG
Pig100522705OPA1OPA1, mitochondrial dynamin like GTPase9823OMA, EggNOG
Opossum100013661OPA1OPA1, mitochondrial dynamin like GTPase13616Inparanoid, OMA, EggNOG
Chicken424900OPA1OPA1, mitochondrial dynamin like GTPase9031CGNC:5403Inparanoid, OMA, EggNOG
Anole lizard100557914opa1OPA1, mitochondrial dynamin like GTPase28377Inparanoid, OMA, EggNOG
Xenopus100145638opa1optic atrophy 1 (autosomal dominant)8364XB-GENE-989058Inparanoid, OMA, EggNOG
Zebrafish492332opa1optic atrophy 1 (autosomal dominant)7955ZDB-GENE-041114-7Inparanoid, OMA, EggNOG
C. elegans174476eat-3hypothetical protein6239Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    small GTPase    /    Dynamin-like 120 kDa protein, mitochondrial
protein    /    enzyme modulator    /    microtubule family cytoskeletal protein    /    Dynamin-like 120 kDa protein, mitochondrial
protein    /    enzyme modulator    /    hydrolase    /    Dynamin-like 120 kDa protein, mitochondrial
DTO Classes
protein    /    Enzyme modulator    /    G-protein    /    Small GTPase    /    Dynamin-like 120 kDa protein, mitochondrial

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelVerfügbarkeitDetails anzeigen

Associated Antibodies

NameSpecificationsSpecies reactivityAnwendungVerfügbarkeitDetails anzeigen

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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