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| Beschreibung | Tyrosine-protein kinase JAK2 |
|---|
Gene and Protein Information
| Gene ID | 3717 |
|---|---|
| Uniprot Accession IDs | O60674 O14636 O75297 |
| Ensembl ID | ENSP00000371067 |
| Symbol | JTK10 THCYT3 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
| Sequence | MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Steuer-ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 464979 | JAK2 | Janus kinase 2 | 9598 | VGNC:4770 | OMA, EggNOG |
| Macaque | 694184 | JAK2 | Janus kinase 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 16452 | Jak2 | Janus kinase 2 | 10090 | MGI:96629 | Inparanoid, OMA, EggNOG |
| Rat | 24514 | Jak2 | Janus kinase 2 | 10116 | RGD:2939 | Inparanoid, OMA |
| Dog | 484185 | JAK2 | Janus kinase 2 | 9615 | VGNC:42176 | Inparanoid, OMA |
| Horse | 100051487 | JAK2 | Janus kinase 2 | 9796 | VGNC:19213 | Inparanoid, OMA |
| Cow | 525246 | JAK2 | Janus kinase 2 | 9913 | VGNC:30365 | Inparanoid, OMA |
| Pig | 397201 | JAK2 | Janus kinase 2 | 9823 | Inparanoid, OMA | |
| Opossum | 100017930 | JAK2 | Janus kinase 2 | 13616 | Inparanoid, OMA | |
| Platypus | 100074305 | JAK2 | Janus kinase 2 | 9258 | Inparanoid, OMA | |
| Chicken | 374199 | JAK2 | Janus kinase 2 | 9031 | CGNC:11173 | Inparanoid, OMA |
| Anole lizard | 100552375 | jak2 | Janus kinase 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 100036599 | jak2 | Janus kinase 2 (a protein tyrosine kinase) | 8364 | XB-GENE-483712 | Inparanoid, OMA |
| Zebrafish | 30298 | jak2b | Janus kinase 2b | 7955 | ZDB-GENE-980526-123 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / JAKA family / Tyrosine-protein kinase jak2
protein / Kinase / Protein kinase / TK group / JAKA family / Tyrosine-protein kinase jak2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Verfügbarkeit | Details anzeigen |
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Associated Antibodies
| Name | Specifications | Species reactivity | Anwendung | Verfügbarkeit | Details anzeigen |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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