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SIRT6

BeschreibungNAD-dependent protein deacetylase sirtuin-6

Gene and Protein Information

Gene ID51548
Uniprot Accession IDs Q8N6T7 B2RCD0 O75291 Q6IAF5 Q6PK99 Q8NCD2 Q9BSI5 Q9BWP3 Q9NRC7 Q9UQD1
Ensembl ID ENSP00000337332
Symbol SIR2L6 SIR2L6
FamilyBelongs to the sirtuin family. Class IV subfamily.
Sequence
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameSteuer-IDOther Gene IDSources
Chimp737026SIRT6sirtuin 69598VGNC:12101OMA, EggNOG
Macaque714545SIRT6sirtuin 69544Inparanoid, OMA, EggNOG
Mouse50721Sirt6sirtuin 610090MGI:1354161Inparanoid, OMA, EggNOG
Rat299638Sirt6sirtuin 610116RGD:1305216Inparanoid, OMA, EggNOG
Dog485045SIRT6sirtuin 69615VGNC:46187Inparanoid, OMA, EggNOG
Cow535416SIRT6sirtuin 69913VGNC:34635Inparanoid, OMA, EggNOG
Pig100126274SIRT6sirtuin 69823Inparanoid, OMA, EggNOG
Opossum100022578SIRT6sirtuin 613616Inparanoid, OMA, EggNOG
Platypus100091769SIRT6sirtuin 69258Inparanoid, OMA, EggNOG
Chicken428332SIRT6sirtuin 69031CGNC:850Inparanoid, OMA, EggNOG
Xenopus394980sirt6sirtuin 68364XB-GENE-5929105Inparanoid, OMA, EggNOG
C. elegans182284sir-2.4NAD-dependent protein deacetylase sir-2.46239Inparanoid, OMA, EggNOG
Fruitfly41254Sirt6Sirtuin 67227FBgn0037802Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Histone deacetylase    /    HDAC class III    /    NAD-dependent protein deacetylase sirtuin-6

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelVerfügbarkeitDetails anzeigen

Associated Antibodies

NameSpecificationsSpecies reactivityAnwendungVerfügbarkeitDetails anzeigen

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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