TAS 301 - 10mM in DMSO , CAS No.193620-69-8

CAS: 193620-69-8 Cat. No.: T422362 Summenformel: C₂₃H₁₉NO₃ Molekulargewicht: 357.4 PubChem CID: 9885087

GRADE & PURITY 10mM in DMSO

Synonyms

HY-18965 | DTXSID80432401 | FT-0700251 | 2,2-Dimethylcyclohexanone, 92% | 3-[bis-(4-methoxy-phenyl)-methylene]-1,3-dihydro-indol-2-one | CHEBI:92970 | Tas 301 | AKOS024458201 | 3-[bis(4-methoxyphenyl)methylene]-oxindole | 3-[BIS(4-METHOXYPHENYL)METHYLIDEN

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyme

HY-18965 | DTXSID80432401 | FT-0700251 | 2,2-Dimethylcyclohexanone, 92% | 3-[bis-(4-methoxy-phenyl)-methylene]-1,3-dihydro-indol-2-one | CHEBI:92970 | Tas 301 | AKOS024458201 | 3-[bis(4-methoxyphenyl)methylene]-oxindole | 3-[BIS(4-METHOXYPHENYL)METHYLIDEN

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Inhibitor of smooth muscle cell migration and proliferation. Blocks voltage-independent calcium influx and downstream PKC signaling. Inhibits neointimal thickening after balloon catheter injury to the rat common carotid artery.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

• Pubchem Sid: 528767347
• Kanonisches Lächeln: COC1=CC=C(C=C1)C(=C2C3=CC=CC=C3NC2=O)C4=CC=C(C=C4)OC
• IUPAC Name: 3-[bis(4-methoxyphenyl)methylidene]-1H-indol-2-one
• InChIKey: KUEYYIJXBRWZIB-UHFFFAOYSA-N
• INCHI: 1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H,1-2H3,(H,24,25)
• Isomere SMILES: COC1=CC=C(C=C1)C(=C2C3=CC=CC=C3NC2=O)C4=CC=C(C=C4)OC
• WGK Deutschland: 3
• PubChem CID: 9885087
• Molekulargewicht: 357.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Indolines Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Secondary carboxylic acid amides Lactams Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Diphenylmethane - Indole or derivatives - Dihydroindole - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Carboxamide group - Secondary carboxylic acid amide - Lactam - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Ether - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 357.400 g/mol
• XLogP3: 4.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 357.136 Da
• Monoisotopic Mass: 357.136 Da
• Topological Polar Surface Area: 47.600 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 530.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1