Teriflunomide impurity 3 - 10mM in DMSO , CAS No.1011244-72-6

CAS: 1011244-72-6 Cat. No.: T656622 Molecular Weight: 280.25 EC Number: 824-254-4 PubChem CID: 13609518

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC 50 of 30 µM. Teriflunomide impurity 3 is less active against COX-2 (IC 50 >100 µM)

In Vitro

Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide; compound 11q) is an amide-bond-reversed compound bearing trifluoromethyl and amino substituents showed potent COX-1-selective inhibitory activity. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:COX-1 30 μM (IC 50 )

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC 50 of 30 µM. Teriflunomide impurity 3 is less active against COX-2 (IC 50 >100 µM).

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)C(F)(F)F)N
• PubChem CID: 13609518
• Molecular Weight: 280.25