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TH023 , CAS No.T1435096
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Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
🌎 Ship to: United States
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
TH023 is an inhibitor for the TLR4 signaling pathway, that targets especially the formation of TLR4 homodimer. TH023 inhibits secreted embryonic alkaline phosphatase in cell HEK-Blue hTLR4 with an IC 50 of 0.354 μM, and inhibits the NO expression in RAW264.7 with an IC 50 of 1.61μM. TH023 also inhibits the activation of NF-κB , reduces the nuclear translocation of NF-κB p65. TH023 exhibits anti-inflammatory efficacy in LPS -induced mouse acute sepsis model, and ameliorates the mouse lung injury.
Specifications
Storage
Store at -20°C
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Namen und Kennungen
| Molekulargewicht | 430.88 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Lösungsrechner
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Häufig gestellte Fragen
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is T1435096, the molecular formula is C22H21ClF2N4O, and the molecular weight is 430.88 g/mol.
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