Thalidomide-OH - ≥99% , CAS No.5054-59-1

CAS: 5054-59-1 Cat. No.: T303826 Molecular Weight: 274.23 EC Number: 826-734-9
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
SY233142 | 4-hydroxy-2-(2,6-dioxo(3-piperidyl))isoindoline-1,3-dione | US11059801, Compound D-1 | ZKA69498 | 2-(2,6-dioxo-piperidine-3-yl)-4-hydroxy-isoindole-1,3-dione | 4-Hydroxy thalidomide, (+/-)- | SKEXQIJIXQSFRX-UHFFFAOYSA-N | XMPJICVFSDYOEG-UHFFFAO
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
T303826-100mg
3

$221.90

$309.90
Save $88.00 (28.40%)
500mg
T303826-500mg
3

$622.90

$755.90
Save $133.00 (17.59%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
SY233142 | 4-hydroxy-2-(2, 6-dioxo(3-piperidyl))isoindoline-1, 3-dione | US11059801, Compound D-1 | ZKA69498 | 2-(2, 6-dioxo-piperidine-3-yl)-4-hydroxy-isoindole-1, 3-dione | 4-Hydroxy thalidomide, (+/-)- | SKEXQIJIXQSFRX-UHFFFAOYSA-N | XMPJICVFSDYOEG-UHFFFAO
Specifications & Purity
≥99%
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid504766723
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504766723
Canonical SmilesC1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O
IUPAC Name2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindole-1,3-dione
InChIKeyXMPJICVFSDYOEG-UHFFFAOYSA-N
INCHI1S/C13H10N2O5/c16-8-3-1-2-6-10(8)13(20)15(12(6)19)7-4-5-9(17)14-11(7)18/h1-3,7,16H,4-5H2,(H,14,17,18)
Isomeric SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)O
Molecular Weight 274.23
Reaxy-Rn 1594237
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1594237&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassIsoindoles and derivatives
SubclassIsoindolines
Intermediate Tree Nodes Isoindolones
Direct ParentPhthalimides
Alternative Parents Alpha amino acids and derivatives  Isoindoles  Piperidinediones  Delta lactams  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  N-substituted carboxylic acid imides  Vinylogous acids  N-unsubstituted carboxylic acid imides  Dicarboximides  Azacyclic compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Phthalimide - Alpha-amino acid or derivatives - Isoindole - Piperidinedione - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Delta-lactam - Phenol - Piperidinone - Carboxylic acid imide, n-substituted - Benzenoid - Piperidine - Carboxylic acid imide - Dicarboximide - Carboxylic acid imide, n-unsubstituted - Vinylogous acid - Lactam - Azacycle - Carboxylic acid derivative - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phthalimides. These are aromatic heterocyclic compounds containing a 1,3-dioxoisoindoline moiety. They are imide derivatives of phthalic anhydrides.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALB Tchem Serum albumin (2651 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PBMC (10003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRBN Tclin Protein cereblon (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRBN Tclin Cereblon/Ikaros (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
K2108420Certificate of AnalysisSep 09, 2024 T303826
K2108421Certificate of AnalysisSep 09, 2024 T303826
Chemical and Physical Properties
Boil Point(°C)568.3±45.0 °C(Predicted)
Melt Point(°C)273-275 °C
Molecular Weight274.230 g/mol
XLogP30.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count1
Exact Mass274.059 Da
Monoisotopic Mass274.059 Da
Topological Polar Surface Area104.000 Ų
Heavy Atom Count20
Formal Charge0
Complexity503.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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