TLR9-IN-1 - ≥99% , CAS No.2226366-86-3

CAS: 2226366-86-3 Cat. No.: T650464 Molecular Weight: 421.54

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC 50 value of 7 nM for human TLR9 . TLR9-IN-1 can be used for researching diseases associated with undesirable immune response

In Vitro

TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC 50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:human TLR9 7 nM (IC 50 )

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC 50 value of 7 nM for human TLR9 . TLR9-IN-1 can be used for researching diseases associated with undesirable immune response.

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: O=C(C1CCN(CC1)C2=NN=CC3=CN(C4=CC=C(C)C=C4)N=C32)NCCCN(C)C
• Molecular Weight: 421.54

Chemical and Physical Properties

• Solubility: DMSO : 500 mg/mL (1186.13 mM; Need ultrasonic)