Tobramycin - Moligand™, ≥98%, Potency ≥900uG/mg , Agonist of TAS2R20, CAS No.32986-56-4, Agonist of TAS2R20

Name: Tobramycin - Moligand™, ≥98%, Potency ≥900uG/mg , Agonist of TAS2R20, CAS No.32986-56-4, Agonist of TAS2R20
SKU: T100847
Availability: InStock

CAS: 32986-56-4 Cat. No.: T100847 Summenformel: C₁₈H₃₇N₅O₉ Molekulargewicht: 467.51 Beilstein Registry Number: 1357507 EG-Nummer: 251-322-5 PubChem CID: 36294

71 Citations COA

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GRADE & PURITY Moligand™ ? ≥98% Potency ≥900uG/mg

Synonyms

TOBRADEX ST COMPONENT TOBRAMYCIN | TOBRAMYCIN (MART.) | TOBRAMYCIN [WHO-DD] | Tobramicina | Tobramycin,(S) | AT02 - Tobramycin | Spectrum_001072 | Nebicin | (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Übersicht Specifications Produkteigenschaften Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften FAQs und Artikel Citations of This Product Lösungsrechner Bewertungen

🧪

Why this grade

Moligand™, ≥98%, Potency ≥900uG/mg Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 71 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Tobramycin is an aminoglycoside antibiotic with similar structure to the kanamycins and gentamycins. It is useful for respiratory infection and cystic fibrosis research. Tobramycin is an aminoglycoside antibiotic.

Specifications

Synonyme

Spezifikationen & Reinheit

Moligand™, ≥98%, Potency ≥900uG/mg

Biochemische und physiologische Mechanismen

Primary Target myeloperoxidase-dependent oxidant cell injury.Inhibits ribosomal translation. Aminoglycoside antibiotic which binds 30S ribosomal subunit A, preventing functional protein production. Effective against gram-negative bacteria.

Storage

Store at 2-8°C,Argon charged

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

AGONIST

Mechanismus der Wirkung

Agonist of TAS2R20

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥98%

Produkteigenschaften

ALogP

-6.2

Namen und Kennungen

Pubchem Sid

508813554

Kanonisches Lächeln

C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N

IUPAC Name

(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol

InChIKey

NLVFBUXFDBBNBW-PBSUHMDJSA-N

INCHI

1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1

Isomere SMILES

C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N

WGK Deutschland

RTECS

WK2100000

PubChem CID

36294

Molekulargewicht

467.51

Beilstein

1357507

Reaxy-Rn

1357507

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Klasse Organooxygen compounds
    - Subclass Carbohydrates and carbohydrate conjugates
      - Ebene5 Aminosaccharides
        Ebene6 Aminoglycosides
        Ebene7 Aminocyclitol glycosides
        Ebene8 2-deoxystreptamine aminoglycosides
        Ebene9 4,6-disubstituted 2-deoxystreptamines

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Klasse	Organooxygen compounds
Subclass	Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes	Aminosaccharides - Aminoglycosides - Aminocyclitol glycosides - 2-deoxystreptamine aminoglycosides
Direct Parent	4,6-disubstituted 2-deoxystreptamines
Alternative Parents	O-glycosyl compounds Aminocyclitols and derivatives Cyclohexylamines Cyclohexanols Oxanes Monosaccharides 1,2-aminoalcohols Oxacyclic compounds Acetals Primary alcohols Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	4,6-disubstituted 2-deoxystreptamine - Glycosyl compound - O-glycosyl compound - Aminocyclitol or derivatives - Cyclohexanol - Cyclohexylamine - Cyclitol or derivatives - Monosaccharide - Oxane - Cyclic alcohol - 1,2-aminoalcohol - Secondary alcohol - Organoheterocyclic compound - Acetal - Oxacycle - Alcohol - Organonitrogen compound - Primary aliphatic amine - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Amine - Primary alcohol - Primary amine - Aliphatic heteromonocyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as 4,6-disubstituted 2-deoxystreptamines. These are 2-deoxystreptamine aminoglycosides that a glycosidically linked to a pyranose of furanose unit at the C4- and C6-positions.
External Descriptors	amino cyclitol glycoside
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

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TAS2R20 Tchem Taste receptor type 2 member 20 (0 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)

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EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)

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CA2 Tclin Carbonic anhydrase II (17698 Activities)

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ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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HMGCR Tclin HMG-CoA reductase (2475 Activities)

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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

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INSR Tclin Insulin receptor (5558 Activities)

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PGR Tclin Progesterone receptor (8562 Activities)

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ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)

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CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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AR Tclin Androgen Receptor (11781 Activities)

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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ACE Tclin Angiotensin-converting enzyme (1423 Activities)

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DRD2 Tclin Dopamine D2 receptor (23596 Activities)

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MAOA Tclin Monoamine oxidase A (11911 Activities)

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CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

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DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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DRD4 Tchem Dopamine D4 receptor (7907 Activities)

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ACHE Tclin Acetylcholinesterase (18204 Activities)

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PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

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HRH2 Tclin Histamine H2 receptor (5428 Activities)

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ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)

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MAOB Tclin Monoamine oxidase B (8835 Activities)

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HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)

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ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

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CALCR Tclin Calcitonin receptor (2215 Activities)

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SLC6A4 Tclin Serotonin transporter (12625 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH1 Tclin Histamine H1 receptor (7573 Activities)

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ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)

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OPRM1 Tclin Mu opioid receptor (19785 Activities)

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DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)

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OPRD1 Tclin Delta opioid receptor (15096 Activities)

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OPRK1 Tclin Kappa opioid receptor (16155 Activities)

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SLC6A3 Tclin Dopamine transporter (10535 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESR2 Tclin Estrogen receptor beta (9272 Activities)

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CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)

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ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)

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CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)

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Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)

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Mc4r Melanocortin receptor 4 (1205 Activities)

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Ltc4s Leukotriene C4 synthase (1 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Sigmar1 Sigma opioid receptor (160 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Npy1r Neuropeptide Y receptor type 1 (8 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cckar Cholecystokinin A receptor (90 Activities)

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Nos2 Nitric oxide synthase, inducible (3573 Activities)

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Mapk1 MAP kinase ERK2 (650 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Hdac6 Histone deacetylase 6 (222 Activities)

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Mmp9 Matrix metalloproteinase 9 (38 Activities)

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rev Human immunodeficiency virus type 1 REV (13 Activities)

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Streptococcus sanguinis (314 Activities)

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Streptococcus pneumoniae (31063 Activities)

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Enterococcus (1748 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Burkholderia cepacia (649 Activities)

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Pseudomonas putida (467 Activities)

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Legionella pneumophila (143 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Proteus vulgaris (5823 Activities)

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Providencia rettgeri (925 Activities)

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Salmonella typhimurium (15756 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Staphylococcus haemolyticus (1695 Activities)

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Staphylococcus hominis (482 Activities)

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Acinetobacter (437 Activities)

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Acinetobacter baumannii (41033 Activities)

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Acinetobacter calcoaceticus (618 Activities)

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Acinetobacter sp. (243 Activities)

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Moraxella catarrhalis (3334 Activities)

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Enterobacteriaceae (669 Activities)

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Citrobacter koseri (193 Activities)

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Citrobacter freundii (1864 Activities)

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Klebsiella aerogenes (4963 Activities)

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Escherichia coli (133304 Activities)

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Klebsiella oxytoca (929 Activities)

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Morganella morganii (1291 Activities)

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Proteus mirabilis (3894 Activities)

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Providencia stuartii (425 Activities)

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Salmonella (646 Activities)

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Serratia marcescens (3237 Activities)

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Shigella sonnei (625 Activities)

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Aeromonas hydrophila (292 Activities)

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Haemophilus influenzae (8812 Activities)

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Staphylococcus warneri (476 Activities)

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Streptococcus salivarius (87 Activities)

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Streptococcus sp. (212 Activities)

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Streptococcus mutans (2687 Activities)

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Wirkungsmechanismen

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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15 results found

Lot Number	Certificate Type	Datum	Artikel
B2604385	Certificate of Analysis	Jan 13, 2026	T100847
B2604387	Certificate of Analysis	Jan 13, 2026	T100847
B2604388	Certificate of Analysis	Jan 13, 2026	T100847
B2604390	Certificate of Analysis	Jan 13, 2026	T100847
H2615137	Certificate of Analysis	Jan 13, 2026	T100847
J2614070	Certificate of Analysis	Jan 13, 2026	T100847
L2118139	Certificate of Analysis	Oct 11, 2025	T100847
L2118140	Certificate of Analysis	Oct 11, 2025	T100847
L2118141	Certificate of Analysis	Oct 11, 2025	T100847
L2118148	Certificate of Analysis	Oct 11, 2025	T100847
D2521289	Certificate of Analysis	Mar 29, 2024	T100847
D2521290	Certificate of Analysis	Mar 29, 2024	T100847
D2515038	Certificate of Analysis	Dec 01, 2021	T100847
J2430272	Certificate of Analysis	Dec 01, 2021	T100847
J2430273	Certificate of Analysis	Dec 01, 2021	T100847

Chemische und physikalische Eigenschaften

Löslichkeit	Soluble in water (94 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), DMSO (<1 mg/ml at 25 °C), methanol, and PBS (pH 7.2) (~10 mg/ml).,
Empfindlichkeit	Moisture sensitive
Brechungsindex	143
Spezifische Drehung [α]	143 ° (C=4, H2O)
Schmelzpunkt (°C)	178°C
Molekulargewicht	467.500 g/mol
XLogP3	-6.200
Hydrogen Bond Donor Count	10
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	6
Exact Mass	467.259 Da
Monoisotopic Mass	467.259 Da
Topological Polar Surface Area	268.000 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	609.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	14
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

FAQs und Artikel

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Citations of This Product

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Other applications43

Drug / compound screening25

Electrochemistry & battery electrolyte15

Organic synthesis — reaction medium14

Extraction & workup solvent6

Spectroscopy sample preparation10

Industrial & non-pharma application2

Chromatography (HPLC / GC / TLC)3

Cytotoxicity screening2

Polymer synthesis & polymerization3

Topical & ophthalmic formulation6

IC50 determination3

Controlled-release & nanoparticle carrier5

Cell proliferation1

Immune cell assay1

Cross-coupling reactions1

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Tobramycin - Moligand™, ≥98%, Potency ≥900uG/mg , Agonist of TAS2R20, CAS No.32986-56-4, Agonist of TAS2R20

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Tobramycin - Moligand™, ≥98%, Potency ≥900uG/mg , Agonist of TAS2R20, CAS No.32986-56-4, Agonist of TAS2R20

Storage & shipping

Quality documents

Literature proof

Übersicht

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Kundenbewertungen

📚 Citations by Application

Need help choosing the grade?

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