TPMPA - Moligand™, ≥98%(HPLC) , Antagonist of GABA A receptor ρ1 subunit;Antagonist of GABA A receptor ρ2 subunit;Antagonist of GABA A receptor ρ3 subunit, CAS No.182485-36-5, Antagonist of GABA A receptor ρ1 subunit;Antagonist of GABA A receptor ρ2 subunit;Antagonist of GABA A receptor ρ3 subunit
TPMPA - Moligand™, ≥98%(HPLC) , Antagonist of GABA A receptor ρ1 subunit;Antagonist of GABA A receptor ρ2 subunit;Antagonist of GABA A receptor ρ3 subunit, CAS No.182485-36-5, Antagonist of GABA A receptor ρ1 subunit;Antagonist of GABA A receptor ρ2 subunit;Antagonist of GABA A receptor ρ3 subunit
GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%(HPLC)
A selective, competitive GABAA-ρantagonist with only minimal effects on GABAAand GABABreceptors (Kbvalues are 2.1μM (antagonist), 320μM (antagonist) and EC50~ 500μM (weak agonist) respectively). Displays 8-fold selectivity for human recombinantρ1 receptor
Storage
Room temperature
Verschickt in
Normal
Note
Moligand™
Aktionsart
ANTAGONIST
Mechanismus der Wirkung
Antagonist of GABA A receptor ρ1 subunit;Antagonist of GABA A receptor ρ2 subunit;Antagonist of GABA A receptor ρ3 subunit
This compound belongs to the class of organic compounds known as hydropyridines. These are compounds containing a hydrogenated pyridine ring (i.e. containing less than the maximum number of double bonds.).
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemische und physikalische Eigenschaften
Löslichkeit
Solvent:water, Max Conc. mg/mL: None, Max Conc. mM: 100
Molekulargewicht
161.140 g/mol
XLogP3
-3.500
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
161.061 Da
Monoisotopic Mass
161.061 Da
Topological Polar Surface Area
49.300 Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
200.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Lösungsrechner
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What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at room temperature.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How is this product shipped?
This product ships under standard ambient conditions. No temperature-controlled packaging is required.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 182485-36-5, the molecular formula is C?H??NO?P, and the molecular weight is 161.14 g/mol. InChIKey MFUKVPOVVKKLRQ-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
Need help choosing the grade?
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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