Triacsin C - Moligand™,≥94%,from Streptomyces aureofaciens , CAS No.76896-80-5

CAS: 76896-80-5 Cat. No.: T139793 Summenformel: C₁₁H₁₇N₃O Molekulargewicht: 207.27 PubChem CID: 9576787

GRADE & PURITY Moligand™, ≥94%, from Streptomyces aureofaciens

Synonyms

2,4,7-Undecatrienal nitrosohydrazone | WS 1228A;FR 900190 | 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene | 2,4,7-Undecatrienal, nitrosohydrazone, (E,E,E)- | (2E,4E,7E)-undecatrienal nitrosohydrazone | FR-900190 | (2E,4E,7E)-2,4,7-Undecatrienal nitros

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator.

Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates IC50=3.6-8.7 μM1–3. Inhibits neutrophil functions

Specifications

Synonyme

2,4,7-Undecatrienal nitrosohydrazone | WS 1228A;FR 900190 | 1-Hydroxy-3-(2',4',7'-undecatrienylidine)triazene | 2,4,7-Undecatrienal, nitrosohydrazone, (E,E,E)- | (2E,4E,7E)-undecatrienal nitrosohydrazone | FR-900190 | (2E,4E,7E)-2,4,7-Undecatrienal nitros

Spezifikationen & Reinheit

Moligand™,≥94%,from Streptomyces aureofaciens

Biochemische und physiologische Mechanismen

Triacsin C is a potent inhibitor of long-chain fatty acyl-CoA synthetase. It can block fatty acid-induced β-cell apoptosis (adipocyte apoptosis) in obese rat models. Additionally, it inhibits the de novo synthesis of triglycerides, diglycerides, and chole

Storage

Protected from light,Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥94%

Namen und Kennungen

Pubchem Sid

528767537

Kanonisches Lächeln

CCCC=CCC=CC=CC=NNN=O

IUPAC Name

N-[(E)-[(2E,4E,7E)-undeca-2,4,7-trienylidene]amino]nitrous amide

InChIKey

NKTGCVUIESDXPU-YLEPRARLSA-N

INCHI

1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+

Isomere SMILES

CCC/C=C/C/C=C/C=C/C=N/NN=O

WGK Deutschland

3

PubChem CID

9576787

Molekulargewicht

207.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Klasse Organonitrogen compounds
      • Subclass Organic nitroso compounds

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Klasse: Organonitrogen compounds
• Subclass: Organic nitroso compounds
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic N-nitroso compounds
• Alternative Parents: Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic n-nitroso compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as organic n-nitroso compounds. These are organic compounds containing a n-nitroso group -NN=O.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in DMSO (25 mg/ml), and methanol (5 mg/ml).
• Empfindlichkeit: Sensitive to light; sensitive to humidity
• Molekulargewicht: 207.270 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 207.137 Da
• Monoisotopic Mass: 207.137 Da
• Topological Polar Surface Area: 53.800 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 255.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1