TT 232, CAS No.147159-51-1

CAS: 147159-51-1 Cat. No.: T287833 Molecular Weight: 947.13 PubChem CID: 6918265

Specifications

Product Name

TT 232, CAS No.147159-51-1

Synonyms

NCGC00249606-01 | CAP 232 | L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-cysteinyl-, cyclic (2-->6)-disulfide | TT-232 | TT2-32 | D-phenylalanyl-cysteinyl-tyrosyl-tryptophyl-lysyl-cysteinyl-threoninamide | Phe-cys-tyr-trp-l

Biochemical and Physiological Mechanisms

Peptide agonist for sst1/sst4somatostatin receptors. Somatostatin analog; inhibits tyrosine kinase activity in human colon tumor cell lines. Demonstrates an antiproliferative effect bothin vitroandin vivoand induces apoptosis in a pancreatic tumor cell li

Sequence

fCYwKCT(Modifications: Disulfide bridge between 2 - 6; Thr-7 = C-terminal amide)

CAS

147159-51-1

Molecule Type

Protein

Storage and Shipping

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Cyclic peptides Phenylalanine and derivatives Macrolactams N-acyl-alpha amino acids and derivatives Alpha amino acid amides Amphetamines and derivatives 3-alkylindoles Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Fatty amides Substituted pyrroles Heteroaromatic compounds Primary carboxylic acid amides Secondary alcohols Lactams Secondary carboxylic acid amides Organic disulfides Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-oligopeptide - Cyclic alpha peptide - Phenylalanine or derivatives - Macrolactam - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - 3-alkylindole - Indole or derivatives - Indole - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Phenol - Fatty acyl - Monocyclic benzene moiety - Fatty amide - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Lactam - Amino acid or derivatives - Organic disulfide - Carboxamide group - Primary carboxylic acid amide - Secondary alcohol - Secondary carboxylic acid amide - Azacycle - Organoheterocyclic compound - Organooxygen compound - Primary amine - Carbonyl group - Organic nitrogen compound - Alcohol - Hydrocarbon derivative - Amine - Organic oxide - Organic oxygen compound - Organonitrogen compound - Primary aliphatic amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

SW480 (6023 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action