UK-371804 HCl - ≥97% , CAS No.256476-36-5

CAS: 256476-36-5 Cat. No.: U414017 Summenformel: C₁₄H₁₇Cl₂N₅O₄S Molekulargewicht: 422.29 PubChem CID: 16657953

QUALITÄT & REINHEIT ≥97%

Synonyms

Alanine,N-​[[1-​[(aminoiminomethyl)​amino]​-​4-​chloro-​7-​isoquinolinyl]​sulfonyl]​-​2-​methyl-​,hydrochloride (1:1)

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Spezifikationen

Synonyme

Alanine,N-​[[1-​[(aminoiminomethyl)​amino]​-​4-​chloro-​7-​isoquinolinyl]​sulfonyl]​-​2-​methyl-​,hydrochloride (1:1)

Spezifikationen & Reinheit

≥97%

Biochemische und physiologische Mechanismen

UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).

Storage

Protected from light,Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥97%

Namen und Kennungen

Pubchem Sid

504768473

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504768473

Kanonisches Lächeln

CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl.Cl

IUPAC Name

2-[[4-chloro-1-(diaminomethylideneamino)isoquinolin-7-yl]sulfonylamino]-2-methylpropanoic acid;hydrochloride

InChIKey

IUBFETAFRGVODB-UHFFFAOYSA-N

INCHI

1S/C14H16ClN5O4S.ClH/c1-14(2,12(21)22)20-25(23,24)7-3-4-8-9(5-7)11(19-13(16)17)18-6-10(8)15;/h3-6,20H,1-2H3,(H,21,22)(H4,16,17,18,19);1H

Isomere SMILES

CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl.Cl

PubChem CID

16657953

Molekulargewicht

422.29

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 42 mg/mL warmed with 50ºC Water: bath (99.45 mM); Water: Insoluble; Ethanol: Insoluble
• Empfindlichkeit: Light sensitive
• Molekulargewicht: 422.300 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 421.038 Da
• Monoisotopic Mass: 421.038 Da
• Topological Polar Surface Area: 169.000 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 644.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 256476-36-5, the molecular formula is C14H17Cl2N5O4S, and the molecular weight is 422.29 g/mol. InChIKey IUBFETAFRGVODB-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.