Uridine - for cell culture, ≥99% , CAS No.58-96-8

CAS: 58-96-8 Cat. No.: U108811 Summenformel: C₉H₁₂N₂O₆ Molekulargewicht: 244.20 Beilstein Registry Number: 754902 EG-Nummer: 200-407-5

QUALITÄT & REINHEIT for Cell culture, ≥99%

Synonyms

1af2 | 1-beta-D-Ribofuranosyluracil | NCGC00017312-02 | Urd | ADENOSINE IMPURITY F (EP IMPURITY) | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione | URIDINE (MART.) | EINECS 200-407-5 | URIDINE [USP IMPU

Storage

Store at 2-8°C

Shipped In

Wet ice

Übersicht

Product Introduction

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is a substrate for nucleotide synthesis in living organisms by de- novo and salvage pathways.

Application

Uridine has been used:

as an inhibitor of schwann cell proliferation in rat dorsal root ganglia (DRG) neurons culture

as a medium supplement for epiblasts culture

as a component of 5-fluoro-2′-deoxyuridine stock solution used for neuronal culture

Spezifikationen

Synonyme

1af2 | 1-beta-D-Ribofuranosyluracil | NCGC00017312-02 | Urd | ADENOSINE IMPURITY F (EP IMPURITY) | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione | URIDINE (MART.) | EINECS 200-407-5 | URIDINE [USP IMPU

Spezifikationen & Reinheit

for cell culture, ≥99%

Storage

Store at 2-8°C

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

für die Zellkultur

Reinheit

≥99%

Namen und Kennungen

Pubchem Sid

488179988

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488179988

Kanonisches Lächeln

C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChIKey

DRTQHJPVMGBUCF-XVFCMESISA-N

INCHI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

Isomere SMILES

C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

WGK Deutschland

3

Molekulargewicht

244.20

Beilstein

754902

Reaxy-Rn

4699706

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4699706&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Klasse Pyrimidine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Klasse: Pyrimidine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrimidine nucleosides
• Alternative Parents: Glycosylamines Pentoses Pyrimidones Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Vinylogous amides Ureas Lactams Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Pyrimidone - Hydropyrimidine - Monosaccharide - Pyrimidine - Vinylogous amide - Tetrahydrofuran - Heteroaromatic compound - Urea - Secondary alcohol - Lactam - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Primary alcohol - Alcohol - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Aromatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: Ribonucleosides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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POLI Tchem DNA polymerase iota (116820 Activities)

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SLC28A1 Tbio Sodium/nucleoside cotransporter 1 (13 Activities)

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SLC28A2 Tchem Sodium/nucleoside cotransporter 2 (91 Activities)

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

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SLC28A3 Tchem Solute carrier family 28 member 3 (29 Activities)

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RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)

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CRBN Tclin Protein cereblon (139 Activities)

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TK Thymidine kinase (276 Activities)

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Cda Cytidine deaminase (37 Activities)

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deoA Thymidine phosphorylase (531 Activities)

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Uck1 Uridine-cytidine kinase 1 (5 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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B4GALT1 Beta-1,4-galactosyltransferase 1 (61 Activities)

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Tk2 Thymidine kinase 2 (53 Activities)

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Mus musculus (284745 Activities)

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3T3-L1 (3664 Activities)

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L1210 (27553 Activities)

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RAW264.7 (28094 Activities)

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Sarcoma-180 (387 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)

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Perknaster fuscus (7 Activities)

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Plasma (328 Activities)

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Ileum (29 Activities)

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Streptavidin (24 Activities)

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Slc29a2 Equilibrative nucleoside transporter 2 (4 Activities)

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ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

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NS1 Nonstructural protein 1 (33327 Activities)

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lgtC Alpha 1,4 galactosyltransferase (29 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in water (50 mg/ml), DMSO, and methanol.
• Spezifische Drehung [α]: 9 ° (C=2, H2O)
• Schmelzpunkt (°C): 163-167°C
• Molekulargewicht: 244.200 g/mol
• XLogP3: -2.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 244.07 Da
• Monoisotopic Mass: 244.07 Da
• Topological Polar Surface Area: 119.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 370.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1