Verteporfin - Moligand™, ≥97% , CAS No.129497-78-5

CAS: 129497-78-5 Cat. No.: V129759 Summenformel: C₄₁H₄₂N₄O₈ Molekulargewicht: 718.79 EG-Nummer: 893-418-5

GRADE & PURITY Moligand™, ≥97%

Synonyms

Visudyne | BPD-MA | CL 318952

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis[1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation.

Specifications

Synonyme

Visudyne | BPD-MA | CL 318952

Spezifikationen & Reinheit

Moligand™, ≥97%

Biochemische und physiologische Mechanismen

Vitepofin is a photosensitizer for photodynamic therapy, which can be used to eliminate abnormal blood vessels in eyes related to macular degeneration and other diseases. Vitipofen can accumulate in abnormal blood vessels. When stimulated by non-thermal r

Storage

Protected from light,Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥97%

Namen und Kennungen

Pubchem Sid

488195426

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488195426

Isomere SMILES

CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5[C@@]6([C@@H](C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C

WGK Deutschland

3

Molekulargewicht

718.79

Reaxy-Rn

14615024

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14615024&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO 100 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
• Empfindlichkeit: Light sensitive
• Molekulargewicht: 718.800 g/mol
• XLogP3: 4.900
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 12
• Exact Mass: 718.3 Da
• Monoisotopic Mass: 718.3 Da
• Topological Polar Surface Area: 174.000 Ų
• Heavy Atom Count: 53
• Formal Charge: 0
• Complexity: 1500.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1