VH 032, propargyl - ≥95%(HPLC) , CAS No.2098799-78-9

CAS: 2098799-78-9 Cat. No.: V287928 Summenformel: C₂₇H₃₄N₄O₅S Molekulargewicht: 526.65 PubChem CID: 138991775

GRADE & PURITY ≥95%(HPLC)

Synonyms

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | VH032-propargyl | VHL ligand 7 | (S,R,S)-AHPC-propargyl

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyme

(2S,4R)-1-((S)-3,3-Dimethyl-2-(2-(prop-2-yn-1-yloxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide | VH032-propargyl | VHL ligand 7 | (S,R,S)-AHPC-propargyl

Spezifikationen & Reinheit

≥95%(HPLC)

Biochemische und physiologische Mechanismen

(S,R,S)-AHPC-propargyl (VH032-propargyl) is a VHL ligand used in the "click reaction" of PROTAC technology.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%(HPLC)

Namen und Kennungen

• Pubchem Sid: 528767634
• Kanonisches Lächeln: CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)COCC#C)O
• IUPAC Name: (2S,4R)-1-[(2S)-3,3-dimethyl-2-[(2-prop-2-ynoxyacetyl)amino]butanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
• InChIKey: UGJHKPQUMUDIQJ-ZFGGDYGUSA-N
• INCHI: 1S/C27H34N4O5S/c1-6-11-36-15-22(33)30-24(27(3,4)5)26(35)31-14-20(32)12-21(31)25(34)28-13-18-7-9-19(10-8-18)23-17(2)29-16-37-23/h1,7-10,16,20-21,24,32H,11-15H2,2-5H3,(H,28,34)(H,30,33)/t20-,21+,24-/m1/s1
• PubChem CID: 138991775
• Molekulargewicht: 526.65

Referenzen

1. Yue Wei, Yunyun Gao, Ruijie Li, Yao Chen, Wenjing Bai, Peirui Zhao, Junchi Hu, Linfeng Li, Xing Wang, Guobing Yin, Yongjun Dang, Xiangqian Kong, Zufeng Guo.  (2026)  High-throughput ligand discovery in living cells using the cellular protein stability enhancement assay.  Acta Pharmaceutica Sinica B,      [PMID:] [10.1016/j.apsb.2026.02.008]