Vimentin-IN-1 - Moligand™, 10 mM in DMSO , CAS No.2319587-80-7
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V1497752
Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin ( VIM ), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1.
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| CAS | 2319587-80-7 |
|---|---|
| Konzentration | 10 mM in DMSO |
| Spezifikationen & Reinheit | Moligand™, 10 mM in DMSO |
| Storage | Store at -80°C |
| Verschickt in | Dry ice packs + Cold packs |
| Product Description | Vimentin-IN-1 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin ( VIM ), to induce hyperphosphorylation of Ser56, resulting selective disruption of mitosis and multinucleation in transformed VIM-expressing mesenchymal cancer cells. Vimentin-IN-1 shows better oral bioavailability and pharmacokinetic profiles than FiVe1. |
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