Vinblastine sulfate - ≥97%(HPLC) , Tubulin inhibitor, CAS No.143-67-9, Tubulin inhibitor

Name: Vinblastine sulfate - ≥97%(HPLC) , Tubulin inhibitor, CAS No.143-67-9, Tubulin inhibitor
SKU: V100993
Availability: InStock

CAS: 143-67-9 Cat. No.: V100993 Summenformel: C₄₆H₅₈N₄O₉·H₂SO₄ Molekulargewicht: 909.05 Beilstein Registry Number: 3659812 EG-Nummer: 205-606-0 PubChem CID: 241902

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GRADE & PURITY ≥97%(HPLC)

Synonyms

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften FAQs und Artikel Citations of This Product Lösungsrechner Bewertungen

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Why this grade

≥97%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyme

Spezifikationen & Reinheit

≥97%(HPLC)

Biochemische und physiologische Mechanismen

Anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Shown to inhibit autophagosome maturation.

Storage

Store at 2-8°C

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Tubulin inhibitor

Reinheit

≥97%(HPLC)

Namen und Kennungen

Pubchem Sid

508815433

Kanonisches Lächeln

CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O

IUPAC Name

methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid

InChIKey

KDQAABAKXDWYSZ-JKDPCDLQSA-N

INCHI

1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+;/m1./s1

Isomere SMILES

CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O

WGK Deutschland

PubChem CID

241902

UN-Nummer

2811

Verpackungsgruppe

Molekulargewicht

909.05

Beilstein

3659812

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Klasse Vinca alkaloids

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Klasse	Vinca alkaloids
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Vinca alkaloids
Alternative Parents	Carbazoles 3-alkylindoles Tricarboxylic acids and derivatives Anisoles Dialkylarylamines Alkyl aryl ethers Aralkylamines Piperidines Organic sulfuric acids N-alkylpyrrolidines Heteroaromatic compounds Pyrroles Methyl esters Tertiary alcohols Trialkylamines Cyclic alcohols and derivatives 1,2-aminoalcohols Amino acids and derivatives Azacyclic compounds Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds Organic oxides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Vinca alkaloid skeleton - Carbazole - 3-alkylindole - Indole - Indole or derivatives - Tricarboxylic acid or derivatives - Anisole - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Alkyl aryl ether - Sulfuric acid - Aralkylamine - Piperidine - Benzenoid - N-alkylpyrrolidine - Cyclic alcohol - Heteroaromatic compound - Organic sulfuric acid or derivatives - Pyrrole - Pyrrolidine - Tertiary alcohol - Methyl ester - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Carboxylic acid ester - 1,2-aminoalcohol - Ether - Organoheterocyclic compound - Carboxylic acid derivative - Azacycle - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Carbonyl group - Organopnictogen compound - Amine - Alcohol - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as vinca alkaloids. These are alkaloids with a dimeric chemical structure composed of an indole nucleus (catharanthine), and a dihydroindole nucleus (vindoline), joined together.
External Descriptors	alkaloid sulfate salt
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

A498 (42825 Activities)

Lot Number	Certificate Type	Datum	Artikel
B2626012	Certificate of Analysis	Aug 18, 2025	V100993
I2508650	Certificate of Analysis	Aug 18, 2025	V100993
I2508651	Certificate of Analysis	Aug 18, 2025	V100993
I1715041	Certificate of Analysis	Apr 09, 2025	V100993

Löslichkeit	Solvent:water, Max Conc. mg/mL: 90.91, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 90.91, Max Conc. mM: 100
Schmelzpunkt (°C)	267°C
Molekulargewicht	909.100 g/mol
XLogP3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	10
Exact Mass	908.388 Da
Monoisotopic Mass	908.388 Da
Topological Polar Surface Area	237.000 Å²
Heavy Atom Count	64
Formal Charge	0
Complexity	1780.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Vinblastine sulfate - ≥97%(HPLC) , Tubulin inhibitor, CAS No.143-67-9, Tubulin inhibitor

Storage & shipping

Quality documents

Literature proof

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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