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VU6000918 - ≥99% , CAS No.2101737-32-8
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GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
🌎 Ship to: United States
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
VU6000918 is a muscarinic acetylcholine (M4) positive allosteric modulator, with an EC 50 of 19 nM for hM4
In Vitro
VU6000918 demonstrates statistically significant AHL reversal (18%) from a low oral dose of 0.03 mg/kg and reaches maximal reversal (74%) from a 3 mg/kg dose, with a resulting in vivo plasma EC 50 of 74 nM (0.66 nM unbound) based on terminal concentrations measured in the study animals (1.5 hr post-administration of 17j). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:EC50: 19 nM (hM4)
Specifications
Spezifikationen & Reinheit
≥99%
Biochemische und physiologische Mechanismen
VU6000918 is a muscarinic acetylcholine (M4) positive allosteric modulator, with an EC 50 of 19 nM for hM4.
Storage
Store at -20°C
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Reinheit
≥99%
Namen und Kennungen
| Kanonisches Lächeln | O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NC3CN(C4=CC=CC(F)=C4F)C3 |
|---|---|
| Molekulargewicht | 389.42 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemische und physikalische Eigenschaften
| Löslichkeit | DMSO : 125 mg/mL (320.99 mM; Need ultrasonic) |
|---|
Lösungsrechner
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