Zaltidine - ≥98% , CAS No.85604-00-8

CAS: 85604-00-8 Cat. No.: Z127855 Summenformel: C₈H₁₀N₆S Molekulargewicht: 222.27 PubChem CID: 56051

GRADE & PURITY ≥98%

Synonyms

(4-(2-METHYLIMIDAZOL-5-YL)-2-THIAZOLYL)QUANIDINE | 85604-00-8 (free base) | A914628 | F84942 | GUANIDINE, (4-(2-METHYL-1H-IMIDAZOL-5-YL)-2-THIAZOLYL)- | GIMNAEMRNXUAQP-UHFFFAOYSA-N | Zaltidina [Spanish] | 1-(4-(2-methyl-1H-imidazol-4-yl)thiazol-2-yl)guani

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyme

(4-(2-METHYLIMIDAZOL-5-YL)-2-THIAZOLYL)QUANIDINE | 85604-00-8 (free base) | A914628 | F84942 | GUANIDINE, (4-(2-METHYL-1H-IMIDAZOL-5-YL)-2-THIAZOLYL)- | GIMNAEMRNXUAQP-UHFFFAOYSA-N | Zaltidina [Spanish] | 1-(4-(2-methyl-1H-imidazol-4-yl)thiazol-2-yl)guani

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

Description:
IC50 Value: N/A
Zaltidine is a H2-receptor antagonist, which has the antisecretory action.
in vitro: N/A
in vivo: In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

Kanonisches Lächeln

CC1=NC=C(N1)C2=CSC(=N2)N=C(N)N

IUPAC Name

2-[4-(2-methyl-1H-imidazol-5-yl)-1,3-thiazol-2-yl]guanidine

InChIKey

GIMNAEMRNXUAQP-UHFFFAOYSA-N

INCHI

1S/C8H10N6S/c1-4-11-2-5(12-4)6-3-15-8(13-6)14-7(9)10/h2-3H,1H3,(H,11,12)(H4,9,10,13,14)

Isomere SMILES

CC1=NC=C(N1)C2=CSC(=N2)N=C(N)N

PubChem CID

56051

Molekulargewicht

222.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Azoles
      • Subclass Thiazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Azoles
• Subclass: Thiazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,4-disubstituted thiazoles
• Alternative Parents: Imidazoles Heteroaromatic compounds Guanidines Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2,4-disubstituted 1,3-thiazole - Heteroaromatic compound - Imidazole - Guanidine - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as 2,4-disubstituted thiazoles. These are compounds containing a thiazole ring substituted at the positions 2 and 3.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

HRH2 Tclin Histamine H2 receptor (5428 Activities)

Discover Target: HRH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Zugehörige Ziele (nicht menschlich)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canis familiaris (36305 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO
• Molekulargewicht: 222.270 g/mol
• XLogP3: 0.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 222.069 Da
• Monoisotopic Mass: 222.069 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 254.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 85604-00-8, the molecular formula is C8H10N6S, and the molecular weight is 222.27 g/mol. InChIKey GIMNAEMRNXUAQP-UHFFFAOYSA-N.

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.