ZD7288 - Moligand™ , Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN3;Channel blocker of HCN4, CAS No.133060-80-7, Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN3;Channel blocker of HCN4

CAS: 133060-80-7 Cat. No.: Z614955 PubChem CID: 123984

GRADE & PURITY Moligand™

Synonyms

Q27089287 | N-ethyl-1,2-dimethyl-6-methylimino-N-phenylpyrimidin-4-amine | SCHEMBL9380740 | N-Ethyl-1,2-dimethyl-6-(methylimino)-N-phenyl-1,6-dihydropyrimidin-4-amine | ZD 7288 | GTPL2359

Storage

Room temperature

Specifications

Synonyme

Q27089287 | N-ethyl-1,2-dimethyl-6-methylimino-N-phenylpyrimidin-4-amine | SCHEMBL9380740 | N-Ethyl-1,2-dimethyl-6-(methylimino)-N-phenyl-1,6-dihydropyrimidin-4-amine | ZD 7288 | GTPL2359

Spezifikationen & Reinheit

Moligand™

Storage

Room temperature

Note

Moligand™

Aktionsart

CHANNEL BLOCKER

Mechanismus der Wirkung

Channel blocker of HCN1;Channel blocker of HCN2;Channel blocker of HCN3;Channel blocker of HCN4

Namen und Kennungen

• Kanonisches Lächeln: CCN(c1cc(=NC)n(c(n1)C)C)c1ccccc1
• IUPAC Name: N-ethyl-1,2-dimethyl-6-methylimino-N-phenylpyrimidin-4-amine
• InChIKey: JABSKGQQWUDVRU-UHFFFAOYSA-N
• INCHI: 1S/C15H20N4/c1-5-19(13-9-7-6-8-10-13)15-11-14(16-3)18(4)12(2)17-15/h6-11H,5H2,1-4H3
• Isomere SMILES: CCN(C1=CC=CC=C1)C2=CC(=NC)N(C(=N2)C)C
• PubChem CID: 123984

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Klasse Organonitrogen compounds
      • Subclass Amines
        • Ebene5 Tertiary amines
          • Ebene6 Tertiary alkylarylamines
            • Ebene7 Alkyldiarylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Klasse: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines - Tertiary alkylarylamines
• Direct Parent: Alkyldiarylamines
• Alternative Parents: Aniline and substituted anilines Aminopyrimidines and derivatives Imidolactams Hydropyrimidines Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Alkyldiarylamine - Aniline or substituted anilines - Aminopyrimidine - Imidolactam - Benzenoid - Pyrimidine - Hydropyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Azacycle - Organoheterocyclic compound - Organopnictogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as alkyldiarylamines. These are tertiary alkylarylamines having two aryl and one alkyl groups attached to the amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

HCN3 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (1 Activities)

Discover Target: HCN3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCN1 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (1 Activities)

Discover Target: HCN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCN2 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (1 Activities)

Discover Target: HCN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HCN4 Tclin Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (1 Activities)

Discover Target: HCN4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Zugehörige Ziele (nicht menschlich)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 256.350 g/mol
• XLogP3: 1.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 256.169 Da
• Monoisotopic Mass: 256.169 Da
• Topological Polar Surface Area: 31.200 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 402.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 133060-80-7. InChIKey JABSKGQQWUDVRU-UHFFFAOYSA-N.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.