zurletrectinib - Moligand™ , Inhibitor of neurotrophic receptor tyrosine kinase 1, CAS No.2403703-30-8, Inhibitor of neurotrophic receptor tyrosine kinase 1

CAS: 2403703-30-8 Cat. No.: Z614990 PubChem CID: 156371488

GRADE & PURITY Moligand™

Synonyms

10H-5,7-Ethenopyrazolo[4,3-g]pyrido[3,2-m]pyrrolo[1,2-k][1,4,6,9,11]oxatetraazacyclotetradecin-11(12H)-one, 2,18-difluoro-1,2,3,13,14,19b-hexahydro-14-methyl-,(2S,14S,19bR)- | zurletrectinib [INN] | Zurletrectinib | GTPL12389 | Zurletrectinib [USAN] | 240

Storage

Room temperature

Specifications

Synonyme

10H-5,7-Ethenopyrazolo[4,3-g]pyrido[3,2-m]pyrrolo[1,2-k][1,4,6,9,11]oxatetraazacyclotetradecin-11(12H)-one, 2,18-difluoro-1,2,3,13,14,19b-hexahydro-14-methyl-,(2S,14S,19bR)- | zurletrectinib [INN] | Zurletrectinib | GTPL12389 | Zurletrectinib [USAN] | 240

Spezifikationen & Reinheit

Moligand™

Storage

Room temperature

Note

Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Inhibitor of neurotrophic receptor tyrosine kinase 1

Namen und Kennungen

• Kanonisches Lächeln: C[C@H]1CNC(=O)Nc2c3nc(ccn3nc2)N2C[C@H](C[C@@H]2c2c(O1)ncc(c2)F)F
• InChIKey: OIBWCYRRWAMTRW-ITDIGPHOSA-N
• INCHI: 1S/C19H19F2N7O2/c1-10-6-23-19(29)25-14-8-24-28-3-2-16(26-17(14)28)27-9-12(21)5-15(27)13-4-11(20)7-22-18(13)30-10/h2-4,7-8,10,12,15H,5-6,9H2,1H3,(H2,23,25,29)/t10-,12-,15+/m0/s1
• Isomere SMILES: C[C@H]1CNC(=O)NC2=C3N=C(C=CN3N=C2)N4C[C@H](C[C@@H]4C5=C(O1)N=CC(=C5)F)F
• PubChem CID: 156371488

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Pyrazolopyrimidines
      • Subclass Pyrazolo[1,5-a]pyrimidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Pyrazolopyrimidines
• Subclass: Pyrazolo[1,5-a]pyrimidines
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrazolo[1,5-a]pyrimidines
• Alternative Parents: Polyhalopyridines O-alkylpyrimidines Dialkylarylamines Methylpyridines Aralkylamines Alkyl aryl ethers 2-halopyridines Imidolactams Hydropyrimidines Pyrrolidines Pyrazoles Heteroaromatic compounds Organic carbonic acids and derivatives Vinyl fluorides Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Hydrazones Fluoroalkenes Carboximidamides Azacyclic compounds Amidines Organopnictogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Pyrazolo[1,5-a]pyrimidine - O-alkylpyrimidine - Polyhalopyridine - Dialkylarylamine - Tertiary aliphatic/aromatic amine - 2-halopyridine - Methylpyridine - Aralkylamine - Alkyl aryl ether - Imidolactam - Pyrimidine - Pyridine - 1,2-dihydropyrimidine - Hydropyrimidine - Heteroaromatic compound - Pyrrolidine - Pyrazole - Azole - Tertiary amine - Carbonic acid derivative - Oxacycle - Azacycle - Fluoroalkene - Haloalkene - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Vinyl halide - Vinyl fluoride - Hydrazone - Ether - Amidine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Alkyl halide - Alkyl fluoride - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as pyrazolo[1,5-a]pyrimidines. These are aromatic heterocyclic compounds containing a pyrazolo[3,4-d]pyrimidine ring system, which consists of a pyrazole ring fused to and sharing exactly one nitrogen atom with a pyrimidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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NTRK1 Tclin High affinity nerve growth factor receptor (0 Activities)

Discover Target: NTRK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2403703-30-8. InChIKey OIBWCYRRWAMTRW-ITDIGPHOSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.