Cathepsin

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  1. Balicatib, Inhibitor of cathepsin K
    CAS: 354813-19-7 Formula: C23H33N5O2 Molecular Weight: 411.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: B288732
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    IUPAC Name
    N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
    SMILES
    CCCN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3(CCCCC3)C(=O)NCC#N
    InChIKey
    LLCRBOWRJOUJAE-UHFFFAOYSA-N
    InChI
    1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H,2-5,10-11,13-18H2,1H3,(H,25,30)(H,26,29show more
    Synonyms
    AAE-581 | AAE581 | N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide | FT-0700298 | AAE581...
  2. E-64d, Inhibitor of cathepsin G
    CAS: 88321-09-9 EC Number: 635-831-3 Formula: C17H30N2O5 Molecular Weight: 342.43
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% protease inhibitor
    ● In Stock — US warehouse, ships to EU* Item #: E123225
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    IUPAC Name
    ethyl (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylate
    SMILES
    CCOC(=O)C1C(O1)C(=O)NC(CC(C)C)C(=O)NCCC(C)C
    InChIKey
    SRVFFFJZQVENJC-IHRRRGAJSA-N
    InChI
    1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1
    Synonyms
    CCG-207846 | BRN 5354546 | compound 2b [PMID: 8765519] | estat | HMS3403C21 | SR-01000759197-2 | EST | MFCD00132883 |...
  3. E-64c
    CAS: 76684-89-4 Formula: C15H26N2O5 Molecular Weight: 314.38
    ● In Stock — US warehouse, ships to EU* Item #: E124386
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    IUPAC Name
    (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
    SMILES
    CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1C(O1)C(=O)O
    InChIKey
    SCMSYZJDIQPSDI-SRVKXCTJSA-N
    InChI
    1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
    Synonyms
    Alcohol, Benzyl | e-64c | E-64-c | BRN 6688621 | SCHEMBL3281530 | CCG-207845 | HO-tES-Leu-NH-CH2-CH2CH(CH3)2 | HY-100...
  4. Z-Leu-Val-Gly-diazomethylketone
    CAS: 119670-30-3 PubChem CID: 73715817 Formula: C22H31N5O5 Molecular Weight: 445.51
    ◐ .Made to order · 8–12 wks Item #: Z345124
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    IUPAC Name
    benzyl N-[1-[[1-[(3-diazo-2-oxopropyl)amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
    SMILES
    CC(C)CC(C(=O)NC(C(C)C)C(=O)NCC(=O)C=[N+]=[N-])NC(=O)OCC1=CC=CC=C1
    InChIKey
    KRMMQWXJLDORCJ-UHFFFAOYSA-N
    InChI
    1S/C22H31N5O5/c1-14(2)10-18(26-22(31)32-13-16-8-6-5-7-9-16)20(29)27-19(15(3)4)21(30)24-11-17(28)12-25-23/h5-9,12,14-15,18-19H,10-11,13H2,1-4H3,(H,24,3show more
  5. SID 26681509
    CAS: 958772-66-2 PubChem CID: 16725315 Formula: C27H33N5O5S Molecular Weight: 539.65
    ● In Stock — US warehouse, ships to EU* Item #: S275500
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    IUPAC Name
    tert-butyl N-[(2S)-1-[2-[2-(2-ethylanilino)-2-oxoethyl]sulfanylcarbonylhydrazinyl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate
    SMILES
    CCC1=CC=CC=C1NC(=O)CSC(=O)NNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)OC(C)(C)C
    InChIKey
    OTIWAYTTYNFEKL-QFIPXVFZSA-N
    InChI
    1S/C27H33N5O5S/c1-5-17-10-6-8-12-20(17)29-23(33)16-38-26(36)32-31-24(34)22(30-25(35)37-27(2,3)4)14-18-15-28-21-13-9-7-11-19(18)21/h6-13,15,22,28H,5,14show more
    Synonyms
    N-[(1,1-dimethylethoxy)carbonyl]-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide,L-tryptophan
  6. L-Arginine-7-amido-4-methylcoumarin hydrochloride
    CAS: 69304-16-1 PubChem CID: 16218867 Formula: C16H21N5O3・xHCl Molecular Weight: 331.37(free base)
    ● In Stock — US warehouse, ships to EU* Item #: L350281
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    IUPAC Name
    (2S)-2-amino-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride
    SMILES
    CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)N.Cl
    InChIKey
    PFLMUQNBZRXRHD-YDALLXLXSA-N
    InChI
    1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0show more
    Synonyms
    DTXSID50585054 | (2S)-2-amino-5-(diaminomethylideneamino)-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride | L...
  7. N-Ethylmaleimide(NEM)
    CAS: 128-53-0 EC Number: 204-892-4 Formula: C6H7NO2 Molecular Weight: 125.13
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Ultra pure ? Ultra-pure grade with very low impurity content across the board. Use for trace analysis, electronics, or processes intolerant of contamination. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: E100553
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    IUPAC Name
    1-ethylpyrrole-2,5-dione
    SMILES
    CCN1C(=O)C=CC1=O
    InChIKey
    HDFGOPSGAURCEO-UHFFFAOYSA-N
    InChI
    1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
    Synonyms
    NEM | maleic acid N-ethylimide | NSC92547 | NSC-92547 | USAF B-121 | ethylmaleimide | HSCI1_000382 | N-ethylmaleimide...
  8. N-Ethylmaleimide(NEM)
    CAS: 128-53-0 EC Number: 204-892-4 Formula: C6H7NO2 Molecular Weight: 125.13
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: E100552
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    Technical Identifiers
    IUPAC Name
    1-ethylpyrrole-2,5-dione
    SMILES
    CCN1C(=O)C=CC1=O
    InChIKey
    HDFGOPSGAURCEO-UHFFFAOYSA-N
    InChI
    1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
    Synonyms
    NEM | maleic acid N-ethylimide | NSC92547 | NSC-92547 | USAF B-121 | ethylmaleimide | HSCI1_000382 | N-ethylmaleimide...
  9. Cathepsin L inhibitor inhibitor
    CAS: 167498-29-5 Formula: C26H26N2O5 Molecular Weight: 446.49
    ◐ .Made to order · 8–12 wks Item #: C343890
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    IUPAC Name
    benzyl N-[(2S)-1-[[(2S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
    SMILES
    C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=C(C=C2)O)C=O)NC(=O)OCC3=CC=CC=C3
    InChIKey
    QVDJMLQSYRSZKC-UPVQGACJSA-N
    InChI
    1S/C26H26N2O5/c29-17-22(15-20-11-13-23(30)14-12-20)27-25(31)24(16-19-7-3-1-4-8-19)28-26(32)33-18-21-9-5-2-6-10-21/h1-14,17,22,24,30H,15-16,18H2,(H,27,show more
    Synonyms
    N-(Benzyloxycarbonyl)-L-phenylalanyl-L-tyrosinal | BDBM50084650 | N-(benzyloxycarbonyl)-phenylalanyl-l-tyrosinal | {(...
  10. 2-Pyrimidinecarbonitrile
    CAS: 14080-23-0 EC Number: 604-202-5 Formula: C5H3N3 Molecular Weight: 105.1
    ● In Stock — US warehouse, ships to EU* Item #: P121628
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    IUPAC Name
    pyrimidine-2-carbonitrile
    SMILES
    C1=CN=C(N=C1)C#N
    InChIKey
    IIHQNAXFIODVDU-UHFFFAOYSA-N
    InChI
    1S/C5H3N3/c6-4-5-7-2-1-3-8-5/h1-3H
    Synonyms
    AM20080306 | 2-Cyanopyrimidine | 2-cyano-pyrimidine | 2-Cyano pyrimidine | pyrimidine-2-carbonitrile | STK503786 | BB...
  11. 2-Pyrimidinecarbonitrile
    CAS: 14080-23-0 Formula: C5H3N3 Molecular Weight: 105.1
    2mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: P421525
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    IUPAC Name
    pyrimidine-2-carbonitrile
    SMILES
    C1=CN=C(N=C1)C#N
    InChIKey
    IIHQNAXFIODVDU-UHFFFAOYSA-N
    InChI
    1S/C5H3N3/c6-4-5-7-2-1-3-8-5/h1-3H
    Synonyms
    AM20080306 | 2-Cyanopyrimidine | 2-cyano-pyrimidine | 2-Cyano pyrimidine | pyrimidine-2-carbonitrile | STK503786 | BB...
  12. 4-Methylesculetin
    CAS: 529-84-0 EC Number: 208-470-0 Formula: C10H8O4 Molecular Weight: 192.17
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M158652
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    IUPAC Name
    6,7-dihydroxy-4-methylchromen-2-one
    SMILES
    CC1=CC(=O)OC2=CC(=C(C=C12)O)O
    InChIKey
    KVOJTUXGYQVLAJ-UHFFFAOYSA-N
    InChI
    1S/C10H8O4/c1-5-2-10(13)14-9-4-8(12)7(11)3-6(5)9/h2-4,11-12H,1H3
    Synonyms
    Z57109126 | 4-Methylesculetol | Pipecolic acid, L- | SPBio_000554 | alpha-Liponsaeure | BSPBio_002064 | SR-0100038989...
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Frequently Asked Questions

What can I find under Cathepsin?
This listing collects compounds associated with Cathepsin within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Cathepsin?
Consider the reported potency of each Cathepsin compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Cathepsin compounds?
Each Cathepsin product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Cathepsin compounds by activity or structure?
Yes. Filter the Cathepsin listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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