Cathepsin

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  1. 4-Methylesculetin
    CAS: 529-84-0 EC Number: 208-470-0 Formula: C10H8O4 Molecular Weight: 192.17
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M424542
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    IUPAC Name
    6,7-dihydroxy-4-methylchromen-2-one
    SMILES
    CC1=CC(=O)OC2=CC(=C(C=C12)O)O
    InChIKey
    KVOJTUXGYQVLAJ-UHFFFAOYSA-N
    InChI
    1S/C10H8O4/c1-5-2-10(13)14-9-4-8(12)7(11)3-6(5)9/h2-4,11-12H,1H3
    Synonyms
    Z57109126 | 4-Methylesculetol | Pipecolic acid, L- | SPBio_000554 | alpha-Liponsaeure | BSPBio_002064 | SR-0100038989...
  2. BML-244
    CAS: 104062-70-6 Formula: C11H21NO3 Molecular Weight: 215.29
    ◐ .Made to order · 8–12 wks Item #: B275192
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    IUPAC Name
    tert-butyl N-(1-oxohexan-2-yl)carbamate
    SMILES
    CCCCC(C=O)NC(=O)OC(C)(C)C
    InChIKey
    OBMGXPJNZKYOQY-UHFFFAOYSA-N
    InChI
    1S/C11H21NO3/c1-5-6-7-9(8-13)12-10(14)15-11(2,3)4/h8-9H,5-7H2,1-4H3,(H,12,14)
    Synonyms
    tert-ButylN-[(2S)-1-oxohexan-2-yl]carbamate
  3. Balicatib, Inhibitor of cathepsin K
    CAS: 354813-19-7 EC Number: 967-672-3 Formula: C23H33N5O2 Molecular Weight: 411.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B423591
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    IUPAC Name
    N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
    SMILES
    CCCN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3(CCCCC3)C(=O)NCC#N
    InChIKey
    LLCRBOWRJOUJAE-UHFFFAOYSA-N
    InChI
    1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H,2-5,10-11,13-18H2,1H3,(H,25,30)(H,26,29show more
    Synonyms
    Balicatib|354813-19-7|AAE581|AAE-581|Balicatib [INN]|N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-...
  4. CA-074 methyl ester
    CAS: 147859-80-1 Formula: C19H31N3O6 Molecular Weight: 397.47
    ● In Stock — US warehouse, ships to EU* Item #: C331659
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    IUPAC Name
    methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylate
    SMILES
    CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC
    InChIKey
    XGWSRLSPWIEMLQ-YTFOTSKYSA-N
    InChI
    1S/C19H31N3O6/c1-5-9-20-16(23)14-15(28-14)17(24)21-13(11(3)6-2)18(25)22-10-7-8-12(22)19(26)27-4/h11-15H,5-10H2,1-4H3,(H,20,23)(H,21,24)/t11-,12-,13-,1show more
    Synonyms
    Bio2_000234 | HMS3886D15 | SCHEMBL1974424 | AKOS027251055 | KBio3_000467 | 1-bromo-4-formylbenzene | CA-074(OMe) | HY...
  5. Calpeptin, Inhibitor of calpain 1;Inhibitor of cathepsin K
    CAS: 117591-20-5 Formula: C20H30N2O4 Molecular Weight: 362.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: C420784
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    Technical Identifiers
    IUPAC Name
    benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate
    SMILES
    CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    PGGUOGKHUUUWAF-ROUUACIJSA-N
    InChI
    1S/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17-show more
    Synonyms
    Isopentanal | KBio3_000476 | Benzylcarbonyl-leu-nleu-H | EX-A2217 | HMS3675M09 | IDI1_033988 | N-benzyloxycarbonyl-L-...
  6. Calpeptin, Inhibitor of calpain 1;Inhibitor of cathepsin K
    CAS: 117591-20-5 Formula: C20H30N2O4 Molecular Weight: 362.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: C274691
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    IUPAC Name
    benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate
    SMILES
    CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    PGGUOGKHUUUWAF-ROUUACIJSA-N
    InChI
    1S/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17-show more
    Synonyms
    Isopentanal | KBio3_000476 | Benzylcarbonyl-leu-nleu-H | EX-A2217 | HMS3675M09 | IDI1_033988 | N-benzyloxycarbonyl-L-...
  7. Cathepsin G Inhibitor
    CAS: 429676-93-7 Formula: C36H33N2O6P Molecular Weight: 620.63
    ● In Stock — US warehouse, ships to EU* Item #: C275652
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    IUPAC Name
    [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid
    SMILES
    CN(C1CCN(CC1)C(=O)C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4C=C3C(=O)C(C5=CC=CC6=CC=CC=C65)P(=O)(O)O
    InChIKey
    GNOZQRKYZJSIPZ-UHFFFAOYSA-N
    InChI
    1S/C36H33N2O6P/c1-37(28-18-20-38(21-19-28)35(40)25-11-3-2-4-12-25)36(41)32-23-27-14-6-5-13-26(27)22-31(32)33(39)34(45(42,43)44)30-17-9-15-24-10-7-8-16show more
    Synonyms
    HY-103351 | DTXSID80431393 | SCHEMBL1613660 | BDBM50139754 | [2-[3-[(1-benzoylpiperidin-4-yl)-methylcarbamoyl]naphtha...
  8. Cathepsin Inhibitor 1
    CAS: 225120-65-0 PubChem CID: 44224135 Formula: C20H24ClN5O2 Molecular Weight: 401.89
    ● In Stock — US warehouse, ships to EU* Item #: C129408
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    IUPAC Name
    5-tert-butyl-N-[(2S)-3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
    SMILES
    CC(C)(C)C1=NN(C(=C1)C(=O)NC(CC2=CC(=CC=C2)Cl)C(=O)NCC#N)C
    InChIKey
    MZRVIHRERYCHBL-HNNXBMFYSA-N
    InChI
    1S/C20H24ClN5O2/c1-20(2,3)17-12-16(26(4)25-17)19(28)24-15(18(27)23-9-8-22)11-13-6-5-7-14(21)10-13/h5-7,10,12,15H,9,11H2,1-4H3,(H,23,27)(H,24,28)/t15-/show more
    Synonyms
    1H-Pyrazole-5-carboxamide, N-[(1S)-1-[(3-chlorophenyl)methyl]-2-[(cyanomethyl)amino]-2-oxoethyl]-3-(1,1-dimethylethyl...
  9. Chymostatin
    CAS: 9076-44-2 Formula: C31H41N7O6 Molecular Weight: 607.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(a mixture of A, B, C)
    ● In Stock — US warehouse, ships to EU* Item #: C113165
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    IUPAC Name
    2-[[1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-[[4-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]pentan-2-yl]amino]-2-oxoethyl]carbamoylamino]-show more
    SMILES
    CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)C(C2CCN=C(N2)N)NC(=O)NC(CC3=CC=CC=C3)C(=O)O
    InChIKey
    MRXDGVXSWIXTQL-UHFFFAOYSA-N
    InChI
    1S/C31H41N7O6/c1-19(2)15-24(27(40)34-22(18-39)16-20-9-5-3-6-10-20)35-28(41)26(23-13-14-33-30(32)36-23)38-31(44)37-25(29(42)43)17-21-11-7-4-8-12-21/h3-show more
    Synonyms
    FT-0623815 | EINECS 257-382-9 | SCHEMBL14029469 | 2-[[1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-[[4-methyl-1-oxo...
  10. E-64
    CAS: 66701-25-5 Formula: C15H27N5O5 Molecular Weight: 357.41
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: E425359
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    Technical Identifiers
    IUPAC Name
    (2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
    SMILES
    CC(C)C[C@H](NC(=O)[C@@H]1O[C@H]1C(O)=O)C(=O)NCCCCNC(N)=N
    InChIKey
    LTLYEAJONXGNFG-DCAQKATOSA-N
    InChI
    1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10show more
    Synonyms
    SCHEMBL4740187 | BDBM50157741 | (2S,3S)-3-(N-{(S)-1-[N-(4-guanidinobutyl)carbamoyl]3-methylbutyl}carbamoyl)oxirane-2-...
  11. E-64c
    CAS: 76684-89-4 Formula: C15H26N2O5 Molecular Weight: 314.38
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: E425884
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    Technical Identifiers
    IUPAC Name
    (2S,3S)-3-[[(2S)-4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
    SMILES
    CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1C(O1)C(=O)O
    InChIKey
    SCMSYZJDIQPSDI-SRVKXCTJSA-N
    InChI
    1S/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1
    Synonyms
    Alcohol, Benzyl | e-64c | E-64-c | BRN 6688621 | SCHEMBL3281530 | CCG-207845 | HO-tES-Leu-NH-CH2-CH2CH(CH3)2 | HY-100...
  12. Gly-Phe-β-naphthylamide
    CAS: 21438-66-4 Formula: C21H21N3O2 Molecular Weight: 347.41
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: G422590
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    Technical Identifiers
    IUPAC Name
    (2S)-2-[(2-aminoacetyl)amino]-N-naphthalen-2-yl-3-phenylpropanamide
    SMILES
    C1=CC=C(C=C1)CC(C(=O)NC2=CC3=CC=CC=C3C=C2)NC(=O)CN
    InChIKey
    YABDXPBHLDPMOA-IBGZPJMESA-N
    InChI
    1S/C21H21N3O2/c22-14-20(25)24-19(12-15-6-2-1-3-7-15)21(26)23-18-11-10-16-8-4-5-9-17(16)13-18/h1-11,13,19H,12,14,22H2,(H,23,26)(H,24,25)/t19-/m0/s1
    Synonyms
    21438-66-4|Glycyl-L-phenylalanine 2-naphthylamide|Gly-phe-naphthylamide|Glycylphenylalanine 2-naphthylamide|gly-phe 2...
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Frequently Asked Questions

What can I find under Cathepsin?
This listing collects compounds associated with Cathepsin within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Cathepsin?
Consider the reported potency of each Cathepsin compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Cathepsin compounds?
Each Cathepsin product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Cathepsin compounds by activity or structure?
Yes. Filter the Cathepsin listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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