CDK

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  1. CDK2-IN-73 (CDK2-IN-4)
    CAS: 2079895-42-2 PubChem CID: 123132899 Formula: C23H18N6O2S Molecular Weight: 442.49
    ● In Stock — US warehouse, ships to EU* Item #: C412291
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    IUPAC Name
    4-[[6-(3-phenylphenyl)-7H-purin-2-yl]amino]benzenesulfonamide
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C4C(=NC(=N3)NC5=CC=C(C=C5)S(=O)(=O)N)N=CN4
    InChIKey
    FUGRWXRQJGJIER-UHFFFAOYSA-N
    InChI
    1S/C23H18N6O2S/c24-32(30,31)19-11-9-18(10-12-19)27-23-28-20(21-22(29-23)26-14-25-21)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-14H,(H2,24,30,31)(H2,25,26,27show more
    Synonyms
    CDK2 inhibitor 73Benzenesulfonamide,4-​[(6-​[1,​1'-​biphenyl]​-​3-​yl-​9H-​purin-​2-​yl)​amino]​-
  2. CDKI-73, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 7;Inhibitor of cyclin dependent kinase 9
    CAS: 1421693-22-2 Formula: C15H15FN6O2S2 Molecular Weight: 394.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: C421562
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    IUPAC Name
    3-[[5-fluoro-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide
    SMILES
    CC1=C(SC(=N1)NC)C2=NC(=NC=C2F)NC3=CC(=CC=C3)S(=O)(=O)N
    InChIKey
    GAIOPWBQKZMUNO-UHFFFAOYSA-N
    InChI
    1S/C15H15FN6O2S2/c1-8-13(25-15(18-2)20-8)12-11(16)7-19-14(22-12)21-9-4-3-5-10(6-9)26(17,23)24/h3-7H,1-2H3,(H,18,20)(H2,17,23,24)(H,19,21,22)
    Synonyms
    GAIOPWBQKZMUNO-UHFFFAOYSA-N | MS-26626 | 3-((5-fluoro-4-(4-methyl-2-(methylamino)thiazol-5-yl)pyrimidin-2-yl)amino)be...
  3. CGP60474
    CAS: 164658-13-3 Formula: C18H18ClN5O Molecular Weight: 355.82
    ● In Stock — US warehouse, ships to EU* Item #: C125354
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    IUPAC Name
    3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol
    SMILES
    C1=CC(=CC(=C1)Cl)NC2=NC=CC(=N2)C3=CC(=NC=C3)NCCCO
    InChIKey
    IYNDTACKOAXKBJ-UHFFFAOYSA-N
    InChI
    1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)
    Synonyms
    8II | BCP27893 | HMS3265E05 | GNF-Pf-88 | HY-11009 | Q27163218 | A910858 | cid_644215 | D97331 | HMS2218H05 | SCHEMBL...
  4. CVT-313, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2
    CAS: 199986-75-9 Formula: C20H28N6O3 Molecular Weight: 400.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: C422433
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    IUPAC Name
    2-[2-hydroxyethyl-[6-[(4-methoxyphenyl)methylamino]-9-propan-2-ylpurin-2-yl]amino]ethanol
    SMILES
    CC(C)N1C=NC2=C(N=C(N=C21)N(CCO)CCO)NCC3=CC=C(C=C3)OC
    InChIKey
    NQVIIUBWMBHLOZ-UHFFFAOYSA-N
    InChI
    1S/C20H28N6O3/c1-14(2)26-13-22-17-18(21-12-15-4-6-16(29-3)7-5-15)23-20(24-19(17)26)25(8-10-27)9-11-28/h4-7,13-14,27-28H,8-12H2,1-3H3,(H,21,23,24)
    Synonyms
    T5490K8I7S | 2,2'-((9-Isopropyl-6-((4-methoxybenzyl)amino)-9H-purin-2-yl)azanediyl)diethanol | Cdk2 Inhibitor III | f...
  5. CVT-313, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2
    CAS: 199986-75-9 Formula: C20H28N6O3 Molecular Weight: 400.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C126650
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    IUPAC Name
    2-[2-hydroxyethyl-[6-[(4-methoxyphenyl)methylamino]-9-propan-2-ylpurin-2-yl]amino]ethanol
    SMILES
    CC(C)N1C=NC2=C(N=C(N=C21)N(CCO)CCO)NCC3=CC=C(C=C3)OC
    InChIKey
    NQVIIUBWMBHLOZ-UHFFFAOYSA-N
    InChI
    1S/C20H28N6O3/c1-14(2)26-13-22-17-18(21-12-15-4-6-16(29-3)7-5-15)23-20(24-19(17)26)25(8-10-27)9-11-28/h4-7,13-14,27-28H,8-12H2,1-3H3,(H,21,23,24)
    Synonyms
    Cdk2 Inhibitor III) | 2(bis-(Hydroxyethyl)amino)-6-(4-methoxybenzylamino)-9-isopropyl-purine | CVT-313 | Cdk2 Inhibit...
  6. Ca2+ channel agonist 1
    CAS: 1402821-24-2 Formula: C19H26N6O Molecular Weight: 354.45
    ● In Stock — US warehouse, ships to EU* Item #: C412431
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    IUPAC Name
    (2R)-2-[[6-(benzylamino)-9-propylpurin-2-yl]amino]butan-1-ol
    SMILES
    CCCN1C=NC2=C(N=C(N=C21)NC(CC)CO)NCC3=CC=CC=C3
    InChIKey
    LKXPLOHGQSEPEM-OAHLLOKOSA-N
    InChI
    1S/C19H26N6O/c1-3-10-25-13-21-16-17(20-11-14-8-6-5-7-9-14)23-19(24-18(16)25)22-15(4-2)12-26/h5-9,13,15,26H,3-4,10-12H2,1-2H3,(H2,20,22,23,24)/t15-/m1/show more
  7. Cdk/Crk inhibitor, Inhibitor of cyclin dependent kinase 6;Inhibitor of cyclin dependent kinase 7;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 784211-09-2 Formula: C23H22Cl2N4O3 Molecular Weight: 473.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: C336669
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    IUPAC Name
    1-(2,6-dichlorophenyl)-6-[[4-(2-hydroxyethoxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one
    SMILES
    CC(C)C1=NN(C2=C1C(=O)NC(=N2)CC3=CC=C(C=C3)OCCO)C4=C(C=CC=C4Cl)Cl
    InChIKey
    RSQPNXBTPUXMQN-UHFFFAOYSA-N
    InChI
    1S/C23H22Cl2N4O3/c1-13(2)20-19-22(29(28-20)21-16(24)4-3-5-17(21)25)26-18(27-23(19)31)12-14-6-8-15(9-7-14)32-11-10-30/h3-9,13,30H,10-12H2,1-2H3,(H,26,2show more
    Synonyms
    Q27075833 | SCHEMBL1179657 | Prednidib | HMS3229E20 | DTXSID60429556 | 1-(2,6-dichlorophenyl)-6-{[4-(2-hydroxyethoxy)...
  8. Cdk1 inhibitor, Inhibitor of cyclin dependent kinase 1
    CAS: 220749-41-7 Formula: C17H11ClN2O Molecular Weight: 294.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: C336671
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    IUPAC Name
    3-[(2-chloro-1H-indol-3-yl)methylidene]-1H-indol-2-one
    SMILES
    C1=CC=C2C(=C1)C(=CC3=C(NC4=CC=CC=C43)Cl)C(=O)N2
    InChIKey
    QJKBRWSJWQVKLY-UHFFFAOYSA-N
    InChI
    1S/C17H11ClN2O/c18-16-12(10-5-1-3-7-14(10)19-16)9-13-11-6-2-4-8-15(11)20-17(13)21/h1-9,19H,(H,20,21)
  9. Cdk1/2 Inhibitor III, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of fms related receptor tyrosine kinase 1
    CAS: 443798-55-8 Formula: C15H13F2N7O2S2 Molecular Weight: 425.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: C336620
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    IUPAC Name
    5-amino-N-(2,6-difluorophenyl)-3-(4-sulfamoylanilino)-1,2,4-triazole-1-carbothioamide
    SMILES
    C1=CC(=C(C(=C1)F)NC(=S)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
    InChIKey
    ARIOBGGRZJITQX-UHFFFAOYSA-N
    InChI
    1S/C15H13F2N7O2S2/c16-10-2-1-3-11(17)12(10)21-15(27)24-13(18)22-14(23-24)20-8-4-6-9(7-5-8)28(19,25)26/h1-7H,(H,21,27)(H2,19,25,26)(H3,18,20,22,23)
    Synonyms
    MS-27488 | Cdk1/2 Inhibitor III | UNII-LFR1253W75 | Cdk1/2InhibitorIII | SCHEMBL1394721 | HMS3229C16 | BDBM6878 | CCG...
  10. Cdk1/5 Inhibitor inhibitor, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 5;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 40254-90-8 Formula: C9H7N5 Molecular Weight: 185.19
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: C336172
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    IUPAC Name
    2H-pyrazolo[4,3-b]quinoxalin-3-amine
    SMILES
    C1=CC2=NC3=C(NN=C3N=C2C=C1)N
    InChIKey
    DWHVZCLBMTZRQM-UHFFFAOYSA-N
    InChI
    1S/C9H7N5/c10-8-7-9(14-13-8)12-6-4-2-1-3-5(6)11-7/h1-4H,(H3,10,12,13,14)
    Synonyms
    GTPL5947 | quinoxaline 1 | HSCI1_000152 | 2H-pyrazolo[4,3-b]quinoxalin-3-amine | BRD-K87932577-001-01-6 | CHEBI:92540...
  11. Cdk2/9 inhibitor
    CAS: 507487-89-0 Formula: C14H12N6O2S Molecular Weight: 328.35
    ◐ .Made to order · 8–12 wks Item #: C336661
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    IUPAC Name
    4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
    SMILES
    CC1=C(SC(=N1)N)C2=NC(=NC=C2)NC3=CC(=CC=C3)[N+](=O)[O-]
    InChIKey
    DYTKVFHLKPDNRW-UHFFFAOYSA-N
    InChI
    1S/C14H12N6O2S/c1-8-12(23-13(15)17-8)11-5-6-16-14(19-11)18-9-3-2-4-10(7-9)20(21)22/h2-7H,1H3,(H2,15,17)(H,16,18,19)
    Synonyms
    SCHEMBL1368256 | DYTKVFHLKPDNRW-UHFFFAOYSA-N | H10755 | 4-(2-Amino-4-methyl-5-thiazolyl)-N-(3-nitrophenyl)-2-pyrimidi...
  12. Cdk4 inhibitor, Inhibitor of cyclin dependent kinase 1;Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4
    CAS: 546102-60-7 EC Number: 111-110-4 Formula: C20H10BrN3O2 Molecular Weight: 404.22
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: C336666
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    IUPAC Name
    6-bromo-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17,19,21-nonaene-12,14-dione
    SMILES
    C1=CC=C2C(=C1)C3=C4C(=C5C6=C(C=C(C=C6)Br)NC5=C3N2)C(=O)NC4=O
    InChIKey
    NMFKDDRQSNVETB-UHFFFAOYSA-N
    InChI
    1S/C20H10BrN3O2/c21-8-5-6-10-12(7-8)23-18-14(10)16-15(19(25)24-20(16)26)13-9-3-1-2-4-11(9)22-17(13)18/h1-7,22-23H,(H,24,25,26)
    Synonyms
    K00024 (cdk4 inhibitor) | SCHEMBL1395043 | DTXSID00416208 | Cdk4 Inhibitor | 2-Bromo-12,13-dihydro-5H-indolo(2,3-a)py...
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Frequently Asked Questions

What can I find under CDK?
This listing collects compounds associated with CDK within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for CDK?
Consider the reported potency of each CDK compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for CDK compounds?
Each CDK product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search CDK compounds by activity or structure?
Yes. Filter the CDK listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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