Checkpoint Kinase (Chk)
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71 products
Popular Products
- WAY-600868● In Stock — US warehouse, ships to EU* Item #: W418170View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-fluorophenyl)-1,3-benzothiazol-2-amine
- SMILES
- C1=CC=C2C(=C1)N=C(S2)NC3=CC=C(C=C3)F
- InChIKey
- KQKQLYWDIYNFJP-UHFFFAOYSA-N
- InChI
- 1S/C13H9FN2S/c14-9-5-7-10(8-6-9)15-13-16-11-3-1-2-4-12(11)17-13/h1-8H,(H,15,16)
- Synonyms
- N-(4-Fluorophenyl)benzo[d]thiazol-2-amine | AKOS000115482 | STL281945 | F84308 | HMS1399A22 | AB00577763-02 | DTXSID1...
- WAY-60086810mM in DMSO● In Stock — US warehouse, ships to EU* Item #: W423543View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-fluorophenyl)-1,3-benzothiazol-2-amine
- SMILES
- C1=CC=C2C(=C1)N=C(S2)NC3=CC=C(C=C3)F
- InChIKey
- KQKQLYWDIYNFJP-UHFFFAOYSA-N
- InChI
- 1S/C13H9FN2S/c14-9-5-7-10(8-6-9)15-13-16-11-3-1-2-4-12(11)17-13/h1-8H,(H,15,16)
- Synonyms
- 348-45-8|N-(4-fluorophenyl)-1,3-benzothiazol-2-amine|Benzothiazol-2-yl-(4-fluoro-phenyl)-amine|N-(4-Fluorophenyl)benz...
- Monalizumab (anti-NKG2A), Antibody of killer cell lectin like receptor C1 (CD159a)CAS: 1228763-95-8Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170483View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- KLRC1
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Baboon, Cynomolgus monkey, Human, Rhesus monkey
- Isotype
- Human IgG4SP
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- CD159 antigen-like family member A | CD159a antigen | CD159a | C-lectin type II protein | killer cell lectin-like rec...
- Prexasertib, Serine/threonine-protein kinase Chk2 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P612922View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile
- SMILES
- COC1=C(C(=CC=C1)OCCCN)C2=CC(=NN2)NC3=NC=C(N=C3)C#N
- InChIKey
- DOTGPNHGTYJDEP-UHFFFAOYSA-N
- InChI
- 1S/C18H19N7O2/c1-26-14-4-2-5-15(27-7-3-6-19)18(14)13-8-16(25-24-13)23-17-11-21-12(9-20)10-22-17/h2,4-5,8,10-11H,3,6-7,19H2,1H3,(H2,22,23,24,25)
- Synonyms
- FT-0700138 | 2-Pyrazinecarbonitrile, 5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)- | 5-[[5-[2-(3...
- CCT241533 hydrochloride◐ .Made to order · 8–12 wks Item #: C647075View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-fluoro-2-[4-[[(3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl]amino]-6,7-dimethoxyquinazolin-2-yl]phenol;hydrochloride
- SMILES
- CC(C)(C1CNCC1NC2=NC(=NC3=CC(=C(C=C32)OC)OC)C4=C(C=CC(=C4)F)O)O.Cl
- InChIKey
- LAKJUTZIXHTMPC-SSPJITILSA-N
- InChI
- show more
- Synonyms
- A908287 | 1431697-96-9 | CCT241533 (hydrochloride) | HY-14715B | F84890 | AKOS030526529 | 4-Fluoro-2-(4-(((3S,4R)-4-(...
- ANI-7◐ .Made to order · 8–12 wks Item #: A648810View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-2-(3,4-dichlorophenyl)-3-(1H-pyrrol-2-yl)prop-2-enenitrile
- SMILES
- C1=CNC(=C1)C=C(C#N)C2=CC(=C(C=C2)Cl)Cl
- InChIKey
- IJJHHDLGGYDXGD-UXBLZVDNSA-N
- InChI
- 1S/C13H8Cl2N2/c14-12-4-3-9(7-13(12)15)10(8-16)6-11-2-1-5-17-11/h1-7,17H/b10-6+
- GDC-0575 dihydrochloride◐ .Made to order · 8–12 wks Item #: G651042View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[(3R)-3-aminopiperidin-1-yl]-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]cyclopropanecarboxamide;dihydrochloride
- SMILES
- C1CC(CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N.Cl.Cl
- InChIKey
- OYMHZTORKRPOBI-YQFADDPSSA-N
- InChI
- show more
- Prexasertib dimesylateSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: P651249View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile;methanesulfonic acid
- SMILES
- COC1=C(C(=CC=C1)OCCCN)C2=CC(=NN2)NC3=NC=C(N=C3)C#N.CS(=O)(=O)O.CS(=O)(=O)O
- InChIKey
- HXYBEKZGRNUTBN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 5-((5-(2-(3-Aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile dimethanesulfonate | SCHEMBL...
- GNE-900Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: G648750View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 12-[4-(piperidin-1-ylmethyl)phenyl]-5,8,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene-4-carbonitrile
- SMILES
- C1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC5=C4C=C(N=C5)C#N)N=C3
- InChIKey
- PPYHOOZGDDPLKM-UHFFFAOYSA-N
- InChI
- 1S/C23H21N5/c24-12-19-11-20-21-10-18(13-26-23(21)27-22(20)14-25-19)17-6-4-16(5-7-17)15-28-8-2-1-3-9-28/h4-7,10-11,13-14H,1-3,8-9,15H2,(H,26,27)
- Synonyms
- 3-(4-(Piperidin-1-ylmethyl)phenyl)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
- CCT244747CAS: 1404095-34-6 Formula: C20H24N8O2 Molecular Weight: 408.46Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: C648940View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(2R)-1-(dimethylamino)propan-2-yl]oxy-5-[[4-methoxy-5-(1-methylpyrazol-4-yl)pyridin-2-yl]amino]pyrazine-2-carbonitrile
- SMILES
- CC(CN(C)C)OC1=NC(=CN=C1C#N)NC2=NC=C(C(=C2)OC)C3=CN(N=C3)C
- InChIKey
- IENLGMOXAQMNEH-CYBMUJFWSA-N
- InChI
- show more
- Synonyms
- 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecar...
- MRT00033659◐ .Made to order · 8–12 wks Item #: M651697View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]acetamide
- SMILES
- CC1=C2C=C(C=NC2=NN1)C3=CC(=CC=C3)NC(=O)C
- InChIKey
- YFBPGSDPFRCNOY-UHFFFAOYSA-N
- InChI
- 1S/C15H14N4O/c1-9-14-7-12(8-16-15(14)19-18-9)11-4-3-5-13(6-11)17-10(2)20/h3-8H,1-2H3,(H,17,20)(H,16,18,19)
- GDC-0425CAS: 1200129-48-1 Formula: C18H19N5O Molecular Weight: 321.38◐ .Made to order · 8–12 wks Item #: G651939View ProductPricing & Pack Sizes
Technical Identifiers
Fast Shipping Same-day shipping on in-stock items
Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for Checkpoint Kinase (Chk)?
Compounds associated with Checkpoint Kinase (Chk) are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Checkpoint Kinase (Chk) sit within Cell Cycle/DNA Damage?
Checkpoint Kinase (Chk) is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Checkpoint Kinase (Chk)?
For compounds listed under Checkpoint Kinase (Chk), check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Checkpoint Kinase (Chk)?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring Checkpoint Kinase (Chk), and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.