c-Kit
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136 products
Popular Products
- CS-2660 (JNJ-38158471)CAS: 951151-97-6 Formula: C15H17ClN6O3 Molecular Weight: 364.7910mM in DMSO◐ .Made to order · 8–12 wks Item #: C427060View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-[6-amino-5-[(E)-methoxyiminomethyl]pyrimidin-4-yl]oxy-2-chlorophenyl]-3-ethylurea
- SMILES
- CCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC(=C2C=NOC)N)Cl
- InChIKey
- BJHCYTJNPVGSBZ-QPSGOUHRSA-N
- InChI
- 1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+
- Synonyms
- Urea,N-[4-[[6-amino-5-[(methoxyimino)methyl]-4-pyrimidinyl]oxy]-2-chlorophenyl]-N'-ethyl-
- Cabozantinib (XL184, BMS-907351), Inhibitor of kinase insert domain receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of ret proto-oncogeneMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: C126195View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- SMILES
- COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
- InChIKey
- ONIQOQHATWINJY-UHFFFAOYSA-N
- InChI
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- Synonyms
- BDBM50021574 | N-[4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]-N inverted exclamation mark -(4-fluorophenyl)cyclopropan...
- DCC-2618CAS: 1225278-16-9 Formula: C26H21F2N5O3 Molecular Weight: 489.47Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: D420967View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-N'-[2,5-difluoro-4-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide
- SMILES
- CN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=CC=C5)F
- InChIKey
- WWOXKWLDMLMYQY-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-(2,5-Difluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenyl)-N′-phenylcyclopropane-1,1-dicarboxamide, DCC 2...
- Dovitinib (TKI258) LactateCAS: 915769-50-5 Formula: C24H29FN6O5 Molecular Weight: 500.53● In Stock — US warehouse, ships to EU* Item #: D413827View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one;2-hydroxypropanoic acid;hydrate
- SMILES
- CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N.O
- InChIKey
- QDPVYZNVVQQULH-UHFFFAOYSA-N
- InChI
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- Synonyms
- InChI=1/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3 | BCP0726000101 | 4-Amino...
- Dovitinib (TKI258) LactateCAS: 915769-50-5 Formula: C24H29FN6O5 Molecular Weight: 500.5310mM in DMSO● In Stock — US warehouse, ships to EU* Item #: D426914View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one;2-hydroxypropanoic acid;hydrate
- SMILES
- CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N.O
- InChIKey
- QDPVYZNVVQQULH-UHFFFAOYSA-N
- InChI
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- Synonyms
- InChI=1/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3 | BCP0726000101 | 4-Amino...
- ISCK03CAS: 945526-43-2 Formula: C19H21N3O2S Molecular Weight: 355.4510mM in DMSO● In Stock — US warehouse, ships to EU* Item #: I427041View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-tert-butyl-N-(4-imidazol-1-ylphenyl)benzenesulfonamide
- SMILES
- CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N3C=CN=C3
- InChIKey
- XQABBHBFHWHMKF-UHFFFAOYSA-N
- InChI
- 1S/C19H21N3O2S/c1-19(2,3)15-4-10-18(11-5-15)25(23,24)21-16-6-8-17(9-7-16)22-13-12-20-14-22/h4-14,21H,1-3H3
- Synonyms
- SCF/c-Kit Signaling Inhibitor | C77268 | HMS3229P07 | AC-35800 | t-Butylphenyl imidazolylphenyl sulfonamide | (4-t-bu...
- Ki20227, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor betaCAS: 623142-96-1 Formula: C24H24N4O5S Molecular Weight: 480.55Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: K425158View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea
- SMILES
- CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
- InChIKey
- SHPFDGWALWEPGS-UHFFFAOYSA-N
- InChI
- 1S/C24H24N4O5S/c1-14(23-26-9-10-34-23)27-24(29)28-17-6-5-15(11-20(17)30-2)33-19-7-8-25-18-13-22(32-4)21(31-3)12-16(18)19/h5-14H,1-4H3,(H2,27,28,29)
- Synonyms
- 1-(4-(6,7-Dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl)-3-(1-(1,3-thiazol-2-yl)ethyl)urea | AKOS015904288 | Urea, N-(4-...
- MDK74978 (Multi-kinase inhibitor I)CAS: 778274-97-8 Formula: C20H17F3N4O3 Molecular Weight: 418.38● In Stock — US warehouse, ships to EU* Item #: M412245View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2-hydroxyethyl)-4-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
- SMILES
- C1=CC(=CC=C1C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F)C(=O)NCCO
- InChIKey
- DEGDCVFNFAOIPU-UHFFFAOYSA-N
- InChI
- 1S/C20H17F3N4O3/c21-20(22,23)30-16-7-5-15(6-8-16)27-18-11-17(25-12-26-18)13-1-3-14(4-2-13)19(29)24-9-10-28/h1-8,11-12,28H,9-10H2,(H,24,29)(H,25,26,27)
- Synonyms
- Multi-kinase inhibitor 1
- Motesanib, Platelet-derived growth factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO◐ .Made to order · 8–12 wks Item #: M424063View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
- SMILES
- CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
- InChIKey
- RAHBGWKEPAQNFF-UHFFFAOYSA-N
- InChI
- 1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
- Synonyms
- N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide | NSC800801 | NSC-800801 | H...
- PDGFRα kinase inhibitor 2CAS: 404844-11-7 Formula: C24H20ClN5O Molecular Weight: 429.90Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: N335699View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(chloromethyl)-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CCl)NC3=NC=CC(=N3)C4=CN=CC=C4
- InChIKey
- WUGWDFMSJPJUEZ-UHFFFAOYSA-N
- InChI
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- Synonyms
- PD119309 | 4-(chloromethyl)-N-{4-methyl-3-[4-(pyridin-3-yl)pyrimidin-2-ylamino]phenyl}benzamide | n-(5-(4-chloromethy...
- Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;InhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: P424022View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
- SMILES
- CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
- InChIKey
- CUIHSIWYWATEQL-UHFFFAOYSA-N
- InChI
- 1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
- Synonyms
- 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide | 5-[[4-[(2,3-d...
- Regorafenib (BAY-734506) MonohydrateCAS: 1019206-88-2 EC Number: 851-928-5 PubChem CID: 24768591 Formula: C21H15ClF4N4O3.H2O Molecular Weight: 500.8310mM in DMSO● In Stock — US warehouse, ships to EU* Item #: R420361View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate
- SMILES
- CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
- InChIKey
- ZOPOQLDXFHBOIH-UHFFFAOYSA-N
- InChI
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- Synonyms
- D10137 | AC-25914 | MFCD17170366 | 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for c-Kit?
Compounds associated with c-Kit are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does c-Kit sit within Protein Tyrosine Kinase/RTK?
c-Kit is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from c-Kit?
For compounds listed under c-Kit, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for c-Kit?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring c-Kit, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.












