Protein Tyrosine Kinase/RTK - c-Kit Supplier | High Purity

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Regorafenib (BAY-734506) Monohydrate
CAS: 1019206-88-2 PubChem CID: 24768591 Formula: C₂₁H₁₅ClF₄N₄O₃.H₂O Molecular Weight: 500.83

≥99%

● In Stock — US warehouse, ships to EU* Item #: R413223
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Technical Identifiers

IUPAC Name

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate

SMILES

CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O

InChIKey
ZOPOQLDXFHBOIH-UHFFFAOYSA-N

InChI

1S/C21H15ClF4N4O3.H2O/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,show more

Synonyms
D10137 | AC-25914 | MFCD17170366 | 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy...
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Ripretinib (DCC-2618), Platelet-derived growth factor receptor alpha inhibitor
CAS: 1442472-39-0 EC Number: 833-454-0 PubChem CID: 71584930 Formula: C₂₄H₂₁BrFN₅O₂ Molecular Weight: 510.36

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: R414158
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IUPAC Name

1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea

SMILES

CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC

InChIKey
CEFJVGZHQAGLHS-UHFFFAOYSA-N

InChI

1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,show more

Synonyms
KIT/PDGFR Inhibitor DCC-2618 | DB14840 | 3-{4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-y...
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SKLB4771 (FLT3-IN-1)
CAS: 1370256-78-2 PubChem CID: 57412684 Formula: C₂₅H₂₇N₇O₃S₂ Molecular Weight: 537.66

Solid Moligand™ ? ≥98%

◐ .Made to order · 8–12 wks Item #: S412688
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IUPAC Name

1-(4-methylphenyl)-3-[5-[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]sulfanyl-1,3,4-thiadiazol-2-yl]urea

SMILES

CC1=CC=C(C=C1)NC(=O)NC2=NN=C(S2)SC3=NC=NC4=C3C=CC(=C4)OCCCN5CCOCC5

InChIKey
LKXFSTAQMOENSC-UHFFFAOYSA-N

InChI

1S/C25H27N7O3S2/c1-17-3-5-18(6-4-17)28-23(33)29-24-30-31-25(37-24)36-22-20-8-7-19(15-21(20)26-16-27-22)35-12-2-9-32-10-13-34-14-11-32/h3-8,15-16H,2,9-show more

Synonyms
1-(5-((7-(3-Morpholinopropoxy)quinazolin-4-yl)thio)-1,3,4-thiadiazol-2-yl)-3-(p-tolyl)urea
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SKLB4771 (FLT3-IN-1)
CAS: 1370256-78-2 PubChem CID: 57412684 Formula: C₂₅H₂₇N₇O₃S₂ Molecular Weight: 537.66

Liquid 10mM in DMSO

◐ .Made to order · 8–12 wks Item #: S421405
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Technical Identifiers

IUPAC Name

1-(4-methylphenyl)-3-[5-[7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]sulfanyl-1,3,4-thiadiazol-2-yl]urea

SMILES

CC1=CC=C(C=C1)NC(=O)NC2=NN=C(S2)SC3=NC=NC4=C3C=CC(=C4)OCCCN5CCOCC5

InChIKey
LKXFSTAQMOENSC-UHFFFAOYSA-N

InChI

1S/C25H27N7O3S2/c1-17-3-5-18(6-4-17)28-23(33)29-24-30-31-25(37-24)36-22-20-8-7-19(15-21(20)26-16-27-22)35-12-2-9-32-10-13-34-14-11-32/h3-8,15-16H,2,9-show more

Synonyms
Urea,N-(4-methylphenyl)-N'-[5-[[7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]thio]-1,3,4-thiadiazol-2-yl]-
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Seralutinib (GB002), Macrophage colony stimulating factor receptor inhibitor
CAS: 1619931-27-9 PubChem CID: 91663352 Formula: C₂₇H₂₇N₅O₃ Molecular Weight: 469.54

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: S419975
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IUPAC Name

N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]amino]ethyl]phenyl]-5-methylpyridine-3-carboxamide

SMILES

CC1=CC(=CN=C1)C(=O)NC2=CC=CC(=C2)C(C)NC3=NC(=CN=C3)C4=CC(=C(C=C4)OC)OC

InChIKey
JHJNPOSPVGRIAN-SFHVURJKSA-N

InChI

1S/C27H27N5O3/c1-17-10-21(14-28-13-17)27(33)31-22-7-5-6-19(11-22)18(2)30-26-16-29-15-23(32-26)20-8-9-24(34-3)25(12-20)35-4/h5-16,18H,1-4H3,(H,30,32)(Hshow more

Synonyms
GTPL10618 | UNII-3P63ZTE3OY | SERALUTINIB [WHO-DD] | 3P63ZTE3OY | HY-109190 | AT11371 | Seralutinib | EX-A5138 | MS-2...
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Sitravatinib (MGCD516), Inhibitor of AXL receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 2;Inhibitor of EPH receptor A3;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of fms relate
CAS: 1123837-84-2 EC Number: 863-087-1 PubChem CID: 25212148 Formula: C₃₃H₂₉F₂N₅O₄S Molecular Weight: 629.68

Moligand™ ? ≥96%

● In Stock — US warehouse, ships to EU* Item #: S414066
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IUPAC Name

1-N'-[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamishow more

SMILES

COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

InChIKey
WLAVZAAODLTUSW-UHFFFAOYSA-N

InChI

1S/C33H29F2N5O4S/c1-43-15-14-36-18-20-2-8-25(38-19-20)29-17-26-30(45-29)28(10-13-37-26)44-27-9-7-23(16-24(27)35)40-32(42)33(11-12-33)31(41)39-22-5-3-2show more

Synonyms
DB15036 | CCG-270287 | EX-A2588 | DTXSID801100124 | 1,1-Cyclopropanedicarboxamide, N-(3-fluoro-4-((2-(5-(((2-methoxye...
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Toceranib phosphate
CAS: 874819-74-6 PubChem CID: 16034840 Formula: C₂₂H₂₅FN₄O₂.H₃O₄P Molecular Weight: 494.45

≥98%

● In Stock — US warehouse, ships to EU* Item #: T413259
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IUPAC Name

5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;phosphoric acid

SMILES

CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O

InChIKey
AOORBROPMMRREB-HBPAQXCTSA-N

InChI

1S/C22H25FN4O2.H3O4P/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27;1-5(2,3)4/h5-6,11-12,25H,3-4,7-10H2,1-show more

Synonyms
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;ph...
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Toceranib phosphate
CAS: 874819-74-6 EC Number: 639-691-4 PubChem CID: 16034840 Formula: C₂₂H₂₅FN₄O₂.H₃O₄P Molecular Weight: 494.45

2mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: T426614
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Technical Identifiers

IUPAC Name

5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;phosphoric acid

SMILES

CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O

InChIKey
AOORBROPMMRREB-HBPAQXCTSA-N

InChI

1S/C22H25FN4O2.H3O4P/c1-13-19(12-17-16-11-15(23)5-6-18(16)26-21(17)28)25-14(2)20(13)22(29)24-7-10-27-8-3-4-9-27;1-5(2,3)4/h5-6,11-12,25H,3-4,7-10H2,1-show more

Synonyms
5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide;ph...
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VEGFR Tyrosine Kinase Inhibitor II, Inhibitor of kinase insert domain receptor
CAS: 269390-69-4 PubChem CID: 9797919 Formula: C₁₉H₁₆ClN₃O Molecular Weight: 337.80

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: V338291
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Technical Identifiers

IUPAC Name

N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benzamide

SMILES

C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)Cl)NCC3=CC=NC=C3

InChIKey
GGPZCOONYBPZEW-UHFFFAOYSA-N

InChI

1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)

Synonyms
GTPL6056 | AKOS030580576 | N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide, VEGF Receptor Tyrosine Kinase I...
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lenvatinib Mesylate, Vascular endothelial growth factor receptor inhibitor
CAS: 857890-39-2 EC Number: 812-398-0 PubChem CID: 11237762 Formula: C₂₁H₁₉N₄O₄Cl.CH₄O₃S Molecular Weight: 522.96

10mM in DMSO

● In Stock — US warehouse, ships to EU* Item #: L426388
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IUPAC Name

4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide;methanesulfonic acid

SMILES

COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl.CS(=O)(=O)O

InChIKey
HWLFIUUAYLEFCT-UHFFFAOYSA-N

InChI

1S/C21H19ClN4O4.CH4O3S/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11;1-5(2,3)4/h4-11H,2-3H2,1H3,(H2,23show more

Synonyms
DTXCID90157572 | CCG-269873 | 3-(2-aminoethyl) pyridine | AC-30100 | BCP11858 | DS-19245 | SB16581 | 6-carbamoyl-4-(3...
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elenestinib, Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of platelet derived growth factor receptor alpha
CAS: 2505078-08-8 PubChem CID: 155190269

Moligand™ ?

◐ .Made to order · 8–12 wks Item #: E610097
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IUPAC Name

2-[4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl]piperazin-1-yl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]pyrazol-1-yl]ethanol

SMILES

C[C@](c1ccc(cc1)F)(c1cnc(nc1)N1CCN(CC1)c1ncnn2c1cc(c2)c1cn(nc1)CCO)N

InChIKey
IPMARPMXSFFZFG-MHZLTWQESA-N

InChI

1S/C27H29FN10O/c1-27(29,21-2-4-23(28)5-3-21)22-14-30-26(31-15-22)36-8-6-35(7-9-36)25-24-12-19(17-38(24)34-18-32-25)20-13-33-37(16-20)10-11-39/h2-5,12-show more

Synonyms
(S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1...
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Flumatinib, Tyrosine-protein kinase ABL inhibitor
CAS: 895519-90-1 Formula: C₂₉H₂₉F₃N₈O Molecular Weight: 562.59

Solid Moligand™ ? ≥98%

◐ .Made to order · 8–12 wks Item #: F610352
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IUPAC Name

4-[(4-methylpiperazin-1-yl)methyl]-N-[6-methyl-5-[(4-pyridin-3-ylpyrimidin-2-yl)amino]pyridin-3-yl]-3-(trifluoromethyl)benzamide

SMILES

CN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)C(=O)Nc1cnc(c(c1)Nc1nccc(n1)c1cccnc1)C

InChIKey
BJCJYEYYYGBROF-UHFFFAOYSA-N

InChI

1S/C29H29F3N8O/c1-19-26(38-28-34-9-7-25(37-28)21-4-3-8-33-16-21)15-23(17-35-19)36-27(41)20-5-6-22(24(14-20)29(30,31)32)18-40-12-10-39(2)11-13-40/h3-9,show more

Synonyms
BCP23797 | AKOS030526971 | N0522 | DB11904 | Flumatinib | EX-A3572 | flumatinib (pseudo INN) | BJCJYEYYYGBROF-UHFFFAO...

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Frequently Asked Questions

Which compounds are listed for c-Kit?

Compounds associated with c-Kit are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.

How does c-Kit sit within Protein Tyrosine Kinase/RTK?

c-Kit is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.

What data should I check before ordering a compound from c-Kit?

For compounds listed under c-Kit, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

How do I find related targets or backup compounds for c-Kit?

Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring c-Kit, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.