c-Met/HGFR

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  1. Pamufetinib mesylate
    CAS: 1688673-09-7 PubChem CID: 118130255 Formula: C28H27FN4O7S2 Molecular Weight: 614.66
    ◐ .Made to order · 8–12 wks Item #: P649401
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    IUPAC Name
    4-[2-fluoro-4-[(2-phenylacetyl)carbamothioylamino]phenoxy]-7-methoxy-N-methylquinoline-6-carboxamide;methanesulfonic acid
    SMILES
    CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F.CS(=O)(=O)O
    InChIKey
    NUYQWFCUOAVQAL-UHFFFAOYSA-N
    InChI
    1S/C27H23FN4O4S.CH4O3S/c1-29-26(34)19-14-18-21(15-24(19)35-2)30-11-10-22(18)36-23-9-8-17(13-20(23)28)31-27(37)32-25(33)12-16-6-4-3-5-7-16;1-5(2,3)4/h3show more
    Synonyms
    4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide mesylate | ZB1547 | AK...
  2. Crizotinib-d5
    CAS: 1395950-84-1 Formula: C21H17D5Cl2FN5O Molecular Weight: 455.37
    ◐ .Made to order · 8–12 wks Item #: C649788
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    IUPAC Name
    3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(3,3,4,5,5-pentadeuteriopiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine
    SMILES
    CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
    InChIKey
    KTEIFNKAUNYNJU-LJIFSARKSA-N
    InChI
    1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/tshow more
  3. MK-8033 hydrochloride
    CAS: 1283000-43-0 PubChem CID: 51030992 Formula: C25H22ClN5O3S Molecular Weight: 508
    ◐ .Made to order · 8–12 wks Item #: M650978
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    IUPAC Name
    1-[5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide;hyshow more
    SMILES
    CN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)N=C2.Cl
    InChIKey
    BKIQDRGTLKPYCL-UHFFFAOYSA-N
    InChI
    1S/C25H21N5O3S.ClH/c1-30-15-20(13-28-30)19-11-23-24(27-12-19)8-7-18-6-5-17(10-22(18)25(23)31)16-34(32,33)29-14-21-4-2-3-9-26-21;/h2-13,15,29H,14,16H2,show more
  4. Ningetinib Tosylate
    CAS: 1394820-77-9 PubChem CID: 73442844 Formula: C38H37FN4O8S Molecular Weight: 728.8
    ◐ .Made to order · 8–12 wks Item #: N651391
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    IUPAC Name
    N-[3-fluoro-4-[7-(2-hydroxy-2-methylpropoxy)quinolin-4-yl]oxyphenyl]-1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carboxamide;4-methylbenzenesulfonic acid
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)O.CC1=C(C(=O)N(N1C)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OCC(C)(C)O)F
    InChIKey
    NAUYISNCVNUUDK-UHFFFAOYSA-N
    InChI
    1S/C31H29FN4O5.C7H8O3S/c1-19-28(30(38)36(35(19)4)21-8-6-5-7-9-21)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(11-12-23(25)26)40-18-31(2,3)show more
    Synonyms
    A903380 | MFCD28142839 | SB17297 | N-(3-Fluoro-4-((7-(2-hydroxy-2-methyl-propoxy)-4-quinolyl)oxy)phenyl)-1,5-dimethyl...
  5. Telisotuzumab vedotin (anti-c-Met), INHIBITOR of Tubulin inhibitor
    CAS: 1714088-51-3
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab183336
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    Technical Identifiers
    Associated targets
    MET
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Reactive species
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    SMILES
    [Telisotuzumab vedotin]
    Synonyms
    AUTS9 antibody | c met antibody | D249 antibody | Hepatocyte growth factor receptor antibody | HGF antibody | HGF rec...
  6. 3-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-4-(1H-Indol-3-Yl)Pyrrolidine-2,5-Dione
    CAS: 1239986-50-5 PubChem CID: 57355660
    ◐ .Made to order · 8–12 wks Item #: P691796
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    Technical Identifiers
    IUPAC Name
    3-(1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraen-3-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
    SMILES
    C1CC2=C3C(=CC=C2)C(=CN3C1)C4C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
    InChIKey
    UCEQXRCJXIVODC-UHFFFAOYSA-N
    InChI
    1S/C23H19N3O2/c27-22-19(16-11-24-18-9-2-1-7-14(16)18)20(23(28)25-22)17-12-26-10-4-6-13-5-3-8-15(17)21(13)26/h1-3,5,7-9,11-12,19-20,24H,4,6,10H2,(H,25,show more
  7. BMS-817378 free base
    CAS: 1174161-69-3 PubChem CID: 44137813 Formula: C24H18ClF2N4O7P Molecular Weight: 578.85
    ◐ .Made to order · 8–12 wks Item #: B691641
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    Technical Identifiers
    IUPAC Name
    [3-[[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]carbamoyl]-5-(4-fluorophenyl)-4-oxopyridin-1-yl]methyl dihydrogen phosphate
    SMILES
    C1=CC(=CC=C1C2=CN(C=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)COP(=O)(O)O)F
    InChIKey
    KXDZWUPUSDCGDD-UHFFFAOYSA-N
    InChI
    1S/C24H18ClF2N4O7P/c25-21-20(7-8-29-23(21)28)38-19-6-5-15(9-18(19)27)30-24(33)17-11-31(12-37-39(34,35)36)10-16(22(17)32)13-1-3-14(26)4-2-13/h1-11H,12Hshow more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under c-Met/HGFR?
This listing collects compounds associated with c-Met/HGFR within our Protein Tyrosine Kinase/RTK area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for c-Met/HGFR?
Consider the reported potency of each c-Met/HGFR compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for c-Met/HGFR compounds?
Each c-Met/HGFR product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search c-Met/HGFR compounds by activity or structure?
Yes. Filter the c-Met/HGFR listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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