c-Met/HGFR

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  1. Narnatumab (anti-RON), INHIBITOR of Macrophage-stimulating protein receptor inhibitor
    CAS: 1188275-92-4
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab176214
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    MST1R
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    c met related tyrosine kinase antibody | CD136 antibody | CD136 antigen antibody | CDw136 antibody | Macrophage stimu...
  2. Rilotumumab (anti-HGF), INHIBITOR of Hepatocyte growth factor inhibitor
    CAS: 872514-65-3
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170950
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    HGF
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG2SA
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    DFNB39 antibody | F TCF antibody | Fibroblast derived tumor cytotoxic factor antibody | Hepatocyte growth factor (hep...
  3. Emibetuzumab (anti-MET), INHIBITOR of Hepatocyte growth factor receptor inhibitor
    CAS: 1365287-97-3
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170880
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    MET
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Rat
    Isotype
    Human IgG4SP
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    AUTS9 antibody | c met antibody | D249 antibody | Hepatocyte growth factor receptor antibody | HGF antibody | HGF rec...
  4. EGFR-IN-8
    CAS: 2407957-87-1 PubChem CID: 139035057 Formula: C32H23ClF3N7O4 Molecular Weight: 662.02
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: E648596
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[3-chloro-4-[5-[3-[[4-(cyclopropanecarbonylamino)-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl]-1,2,4-oxadiazol-3-yl]phenyl]pyridine-3-carboxamidshow more
    SMILES
    C1CC1C(=O)NC2=C(C=C(C=C2)NC(=O)NC3=CC=CC(=C3)C4=NC(=NO4)C5=C(C=C(C=C5)NC(=O)C6=CN=CC=C6)Cl)C(F)(F)F
    InChIKey
    IIUNSVLRVWGJRM-UHFFFAOYSA-N
    InChI
    1S/C32H23ClF3N7O4/c33-25-15-22(38-29(45)19-4-2-12-37-16-19)8-10-23(25)27-42-30(47-43-27)18-3-1-5-20(13-18)39-31(46)40-21-9-11-26(24(14-21)32(34,35)36)show more
    Synonyms
    N-(3-Chloro-4-(5-(3-(3-(4-(cyclopropanecarboxamido)-3-(trifluoromethyl)phenyl)ureido)phenyl)-1,2,4-oxadiazol-3-yl)phe...
  5. Capmatinib dihydrochloride hydrate, Hepatocyte growth factor receptor inhibitor
    CAS: 1865733-40-9 PubChem CID: 122201352 Formula: C23H21Cl2FN6O2 Molecular Weight: 503.36
    ● In Stock — US warehouse, ships to EU* Item #: C649408
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    Technical Identifiers
    IUPAC Name
    2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide;hydrate;dihydrochloride
    SMILES
    CNC(=O)C1=C(C=C(C=C1)C2=NN3C(=CN=C3N=C2)CC4=CC5=C(C=C4)N=CC=C5)F.O.Cl.Cl
    InChIKey
    COWBUPJEEDYWKD-UHFFFAOYSA-N
    InChI
    1S/C23H17FN6O.2ClH.H2O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20;;;/h2-9,11-13H,10H2,1H3,(H,show more
    Synonyms
    NVP-INC280 2HCl.H2O | NVP-INC280 2HCl.H2O | INC-280 2HCl.H2O | INCB28060 2HCl.H2O | INC280 dihydrochloride hydrate | ...
  6. Tyrosine kinase inhibitor
    CAS: 1021950-26-4 PubChem CID: 24956525 Formula: C31H31FN6O5 Molecular Weight: 586.61
    ◐ .Made to order · 8–12 wks Item #: T651028
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-N'-(4-fluorophenyl)-1-N-[4-[[2-(2-morpholin-4-ylethylcarbamoyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]cyclopropane-1,1-dicarboxamide
    SMILES
    C1CC1(C(=O)NC2=CC=C(C=C2)OC3=C4C=C(NC4=NC=C3)C(=O)NCCN5CCOCC5)C(=O)NC6=CC=C(C=C6)F
    InChIKey
    PKOVTRMHYNEBDU-UHFFFAOYSA-N
    InChI
    1S/C31H31FN6O5/c32-20-1-3-21(4-2-20)35-29(40)31(10-11-31)30(41)36-22-5-7-23(8-6-22)43-26-9-12-33-27-24(26)19-25(37-27)28(39)34-13-14-38-15-17-42-18-16show more
    Synonyms
    Tyrosine kinase inhibitor | HY-10421 | AKOS030526205 | BCP04781 | F84306 | 1021950-26-4 | EX-A2282 | MS-30480 | MDK-0...
  7. Glesatinib hydrochloride
    CAS: 1123838-51-6 PubChem CID: 127255607 Formula: C31H28ClF2N5O3S2 Molecular Weight: 656.17
    ◐ .Made to order · 8–12 wks Item #: G646334
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-(4-fluorophenyl)acetamide;hydrochlshow more
    SMILES
    COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=C(C=C5)F)F.Cl
    InChIKey
    TUVXGVPWXBWWEP-UHFFFAOYSA-N
    InChI
    1S/C31H27F2N5O3S2.ClH/c1-40-13-12-34-17-20-4-8-24(36-18-20)28-16-25-30(43-28)27(10-11-35-25)41-26-9-7-22(15-23(26)33)37-31(42)38-29(39)14-19-2-5-21(32show more
  8. Merestinib dihydrochloride
    CAS: 1206801-37-7 PubChem CID: 71604306 Formula: C30H24Cl2F2N6O3 Molecular Weight: 625.45
    ◐ .Made to order · 8–12 wks Item #: M646831
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide;dihydrochloride
    SMILES
    CC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)F.Cl.Cl
    InChIKey
    NNYNNMGUBHQQLZ-UHFFFAOYSA-N
    InChI
    1S/C30H22F2N6O3.2ClH/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15show more
    Synonyms
    N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carbox...
  9. DS-1205b free base
    CAS: 1855860-24-0 PubChem CID: 129110632 Formula: C41H42FN5O7 Molecular Weight: 735.80
    ◐ .Made to order · 8–12 wks Item #: D648321
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[4-[2-amino-5-[4-[[(2R)-1,4-dioxan-2-yl]methoxy]-3-methoxyphenyl]pyridin-3-yl]-3-fluorophenyl]-5-(5-methylpyridin-2-yl)-1-(oxan-4-ylmethyl)-4-oxopyrshow more
    SMILES
    CC1=CN=C(C=C1)C2=CN(C=C(C2=O)C(=O)NC3=CC(=C(C=C3)C4=C(N=CC(=C4)C5=CC(=C(C=C5)OCC6COCCO6)OC)N)F)CC7CCOCC7
    InChIKey
    ZOEILZXFYPPMTR-SSEXGKCCSA-N
    InChI
    1S/C41H42FN5O7/c1-25-3-7-36(44-18-25)33-21-47(20-26-9-11-51-12-10-26)22-34(39(33)48)41(49)46-29-5-6-31(35(42)17-29)32-15-28(19-45-40(32)43)27-4-8-37(3show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under c-Met/HGFR?
This listing collects compounds associated with c-Met/HGFR within our Protein Tyrosine Kinase/RTK area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for c-Met/HGFR?
Consider the reported potency of each c-Met/HGFR compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for c-Met/HGFR compounds?
Each c-Met/HGFR product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search c-Met/HGFR compounds by activity or structure?
Yes. Filter the c-Met/HGFR listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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