c-Met/HGFR
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226 products
Popular Products
- dalmelitinib, Inhibitor of MET proto-oncogene; receptor tyrosine kinaseCAS: 1637658-98-0 PubChem CID: 86302574Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: D609725View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 9-[[8-fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-4-methyl-[1,4]oxazino[3,2-c]quinolin-3-one
- SMILES
- Fc1c2n(cc(c1)c1cnn(c1)C)c(nn2)Sc1cc2c3c(cnc2cc1)N(C(=O)CO3)C
- InChIKey
- MFEXYTURXUZOID-UHFFFAOYSA-N
- InChI
- 1S/C22H16FN7O2S/c1-28-9-13(7-25-28)12-5-16(23)21-26-27-22(30(21)10-12)33-14-3-4-17-15(6-14)20-18(8-24-17)29(2)19(31)11-32-20/h3-10H,11H2,1-2H3
- Synonyms
- compound 4d [PMID: 27288183] | 2H-1,4-Oxazino[3,2-c]quinolin-3(4H)-one, 9-[[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2...
- elzovantinib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of SRC proto-oncogene; non-receptor tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: E610109View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CCN1CC2=C(C=CC(=C2C#N)F)OC(CNC(=O)C3=C4N=C1C=CN4N=C3N)C
- InChIKey
- UUDPUQDMSHQSKH-NSHDSACASA-N
- InChI
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- Synonyms
- CSF1R-IN-2 | TPX-0022
- emzeltrectinib, Inhibitor of Janus kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3CAS: 2223678-97-3 PubChem CID: 134480550Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: E610115View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-amino-5-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
- SMILES
- C1[C@@H](CN([C@H]1c1c(ccc(c1)F)F)c1nc2c(c(nn2cc1)N)C(=O)N)F
- InChIKey
- YFTARXQOKASKBW-JOYOIKCWSA-N
- InChI
- 1S/C17H15F3N6O/c18-8-1-2-11(20)10(5-8)12-6-9(19)7-25(12)13-3-4-26-17(23-13)14(16(22)27)15(21)24-26/h1-5,9,12H,6-7H2,(H2,21,24)(H2,22,27)/t9-,12+/m0/s1
- Synonyms
- GLXC-26845 | GTPL12377 | emzeltrectinib [INN] | 436Z4BZ8HF | SCHEMBL20119394 | 2223678-97-3 | Emzeltrectinib | Pyrazo...
- Glesatinib, Tyrosine-protein kinase TIE-2 inhibitorCAS: 936694-12-1 Formula: C31H27F2N5O3S2 Molecular Weight: 619.70Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: G610571View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-(4-fluorophenyl)acetamide
- SMILES
- COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=C(C=C5)F)F
- InChIKey
- YRCHYHRCBXNYNU-UHFFFAOYSA-N
- InChI
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- Synonyms
- YRCHYHRCBXNYNU-UHFFFAOYSA-N | Adenosine 3,5'-cyclic monophosphoric acid | MG90265gly | D11136 | GTPL9133 | AKOS040741...
- mifanertinib, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 1639014-72-4 PubChem CID: 71613550Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: M611872View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-(3-chloro-4-fluoroanilino)-7-(difluoromethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- CN(C)C/C=C/C(=O)Nc1c(cc2c(c1)c(ncn2)Nc1cc(c(cc1)F)Cl)OC(F)F
- InChIKey
- QPACRWFSFWQNOZ-ONEGZZNKSA-N
- InChI
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- Synonyms
- mifanertinib [INN] | SCHEMBL16547603 | QPACRWFSFWQNOZ-ONEGZZNKSA-N | 774X01FS8V | GLXC-26920 | (2E)-N-[4-(3-chloro-4-...
- Zongertinib, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 2728667-27-2 Formula: C29H29N9O2 Molecular Weight: 535.60Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: Z614983View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[1-[4-[3-methyl-4-(1-methylbenzimidazol-5-yl)oxyanilino]pyrimido[5,4-d]pyrimidin-6-yl]piperidin-4-yl]prop-2-enamide
- SMILES
- Cc1c(ccc(c1)Nc1ncnc2cnc(nc12)N1CCC(CC1)NC(=O)C=C)Oc1cc2c(cc1)n(cn2)C
- InChIKey
- YSGNGFPNTLERCR-UHFFFAOYSA-N
- InChI
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- Synonyms
- EX-A8033 | HY-148810 | Zongertinib | DRH7R67UVL | example I-01 [WO2021213800A1] | N-[1-[4-[3-methyl-4-(1-methylbenzim...
- zurletrectinib, Inhibitor of neurotrophic receptor tyrosine kinase 1CAS: 2403703-30-8 PubChem CID: 156371488Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: Z614990View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- C[C@H]1CNC(=O)Nc2c3nc(ccn3nc2)N2C[C@H](C[C@@H]2c2c(O1)ncc(c2)F)F
- InChIKey
- OIBWCYRRWAMTRW-ITDIGPHOSA-N
- InChI
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- Synonyms
- 10H-5,7-Ethenopyrazolo[4,3-g]pyrido[3,2-m]pyrrolo[1,2-k][1,4,6,9,11]oxatetraazacyclotetradecin-11(12H)-one, 2,18-difl...
- boditrectinibMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: B608180View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-1-piperazin-1-ylprop-2-en-1-one
- SMILES
- C1C[C@@H](N(C1)c1nc2c(cnn2cc1)/C=C/C(=O)N1CCNCC1)c1c(ccc(c1)F)F
- InChIKey
- BQFYCHBYISNPFW-SQZHUTIHSA-N
- InChI
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- Synonyms
- 1940165-80-9 | SCHEMBL17820893 | (R,E)-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1-(...
- resencatinib, Inhibitor of kinase insert domain receptor;Inhibitor of ret proto-oncogeneCAS: 2546117-79-5 PubChem CID: 155296110Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: R613155View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- C[C@](COc1cn2c(c(cn2)C#N)c(c1)c1cnc(cc1)N1CC2CC(C1)N2Cc1cnc(cc1)OC)(C#C)O
- InChIKey
- WNPSOODWDSNATA-DPHZAUTASA-N
- InChI
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- Synonyms
- 6-[(2R)-2-hydroxy-2-methylbut-3-ynoxy]-4-[6-[6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl]pyr...
- risvodetinib, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of ABL proto-oncogene 2; non-receptor tyrosine kinase;Inhibitor of KIT proto-oncogene; receptor tyrosine kinaseCAS: 2031185-00-7 PubChem CID: 122650693Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: R613206View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- Cc1c(cc(cc1)NC(=O)c1ccc(cc1)CN1CCN(CC1)C)Nc1nccc(n1)c1cc(cnc1)c1c(cno1)C
- InChIKey
- ADGOPPKEIZXKAZ-UHFFFAOYSA-N
- InChI
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- Synonyms
- Compound 809 [US20200046699A1] | GTPL12383 | 2031185-00-7 | risvodetinib [INN] | Risvodetinib | BDBM481128 | 2QG2B2XW...
- terevalefim, Hepatocyte growth factor receptor agonistMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: T614382View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[(E)-2-thiophen-2-ylethenyl]-1H-pyrazole
- SMILES
- c1csc(c1)/C=C/c1ccn[nH]1
- InChIKey
- FOHWAQGURRYJFK-ONEGZZNKSA-N
- InChI
- 1S/C9H8N2S/c1-2-9(12-7-1)4-3-8-5-6-10-11-8/h1-7H,(H,10,11)/b4-3+
- Synonyms
- (E)-3-(2-(thiophen-2-yl)vinyl)-1H-pyrazole | 3-[2-(2-thienyl)ethenyl]-1H-Pyrazole | SNV-003 | (e)-5-(2-(thiophen-2-yl...
- zanzalintinib, Inhibitor of AXL receptor tyrosine kinase;Inhibitor of MER proto-oncogene; tyrosine kinase;Inhibitor of MET proto-oncogene; receptor tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: Z614943View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-N'-(4-fluorophenyl)-1-N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]cyclopropane-1,1-dicarboxamide
- SMILES
- CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
- InChIKey
- JSPCKALGNNVYOO-UHFFFAOYSA-N
- InChI
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- Synonyms
- 1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (methylcarbamoyl)quinoln-4- yl]oxyphenyl]cyclopropane-1,1- dicarboxamide ...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What can I find under c-Met/HGFR?
This listing collects compounds associated with c-Met/HGFR within our Protein Tyrosine Kinase/RTK area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for c-Met/HGFR?
Consider the reported potency of each c-Met/HGFR compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for c-Met/HGFR compounds?
Each c-Met/HGFR product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search c-Met/HGFR compounds by activity or structure?
Yes. Filter the c-Met/HGFR listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].