CRM1
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
28 products
Popular Products
- Leptomycin BCAS: 87081-35-4 Formula: C33H48O6 Molecular Weight: 540.73● In Stock — US warehouse, ships to EU* Item #: L102387View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CCC(=CC(C)CC=CC(=CC(C)C(=O)C(C)C(C(C)CC(=CC(=O)O)C)O)C)C=CC1C(C=CC(=O)O1)C
- InChIKey
- YACHGFWEQXFSBS-XYERBDPFSA-N
- InChI
- show more
- Synonyms
- 2,10,12,16,18-Nonadecapentaenoic acid, 19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7...
- KPT-185CAS: 1333151-73-7 Formula: C16H16F3N3O3 Molecular Weight: 355.31● In Stock — US warehouse, ships to EU* Item #: K129656View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- propan-2-yl (Z)-3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoate
- SMILES
- CC(C)OC(=O)C=CN1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F
- InChIKey
- NLNGWFLRRRYNIL-PLNGDYQASA-N
- InChI
- 1S/C16H16F3N3O3/c1-10(2)25-14(23)4-5-22-9-20-15(21-22)11-6-12(16(17,18)19)8-13(7-11)24-3/h4-10H,1-3H3/b5-4-
- Synonyms
- KPT185 | KPT 185 | (2Z)-3-[3-[3-Methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic Acid 1-Methylet...
- KPT-276CAS: 1421919-75-6 Formula: C16H10F8N4O Molecular Weight: 426.26● In Stock — US warehouse, ships to EU* Item #: K129659View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one
- SMILES
- C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F
- InChIKey
- JCHAWRDHMUSLMM-UPHRSURJSA-N
- InChI
- 1S/C16H10F8N4O/c17-14(18)6-27(7-14)12(29)1-2-28-8-25-13(26-28)9-3-10(15(19,20)21)5-11(4-9)16(22,23)24/h1-5,8H,6-7H2/b2-1-
- Synonyms
- 2-Propen-1-one, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-1-(3,3-difluoro-1-azetidinyl)-, (2Z)- | ...
- Eltanexor (KPT-8602), Inhibitor of exportin 1CAS: 1642300-52-4 Formula: C17H10F6N6O Molecular Weight: 428.29Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: E422031View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-2-pyrimidin-5-ylprop-2-enamide
- SMILES
- C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)C=C(C3=CN=CN=C3)C(=O)N
- InChIKey
- JFBAVWVBLRIWHM-AWNIVKPZSA-N
- InChI
- 1S/C17H10F6N6O/c18-16(19,20)11-1-9(2-12(3-11)17(21,22)23)15-27-8-29(28-15)6-13(14(24)30)10-4-25-7-26-5-10/h1-8H,(H2,24,30)/b13-6+
- Synonyms
- 5-Pyrimidineacetamide, alpha-((3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)methylene)-, (alphaE)- | (2E)...
- Eltanexor (KPT-8602), Inhibitor of exportin 1CAS: 1642300-52-4 Formula: C17H10F6N6O Molecular Weight: 428.29Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: E414000View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-2-pyrimidin-5-ylprop-2-enamide
- SMILES
- C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)C=C(C3=CN=CN=C3)C(=O)N
- InChIKey
- JFBAVWVBLRIWHM-AWNIVKPZSA-N
- InChI
- 1S/C17H10F6N6O/c18-16(19,20)11-1-9(2-12(3-11)17(21,22)23)15-27-8-29(28-15)6-13(14(24)30)10-4-25-7-26-5-10/h1-8H,(H2,24,30)/b13-6+
- Synonyms
- 5-Pyrimidineacetamide, alpha-((3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)methylene)-, (alphaE)- | (2E)...
- KPT 251◐ .Made to order · 8–12 wks Item #: K357105View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(Z)-2-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]ethenyl]-1,3,4-oxadiazole
- SMILES
- C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)C=CC3=NN=CO3
- InChIKey
- LDFXTRYMMZGKIC-UPHRSURJSA-N
- InChI
- 1S/C14H7F6N5O/c15-13(16,17)9-3-8(4-10(5-9)14(18,19)20)12-21-6-25(24-12)2-1-11-23-22-7-26-11/h1-7H/b2-1-
- Synonyms
- CRM1 Inhibitor IV | (Z)-2-(2-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)vinyl)-1,3,4-oxadiazole
- KPT 330, Exportin-1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: K357106View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
- SMILES
- C1=CN=C(C=N1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
- InChIKey
- DEVSOMFAQLZNKR-RJRFIUFISA-N
- InChI
- 1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1-
- Synonyms
- J-690156 | Selinexor [USAN:INN] | Xpovio | (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyraz...
- KPT-185CAS: 1333151-73-7 Formula: C16H16F3N3O3 Molecular Weight: 355.3110mM in DMSO● In Stock — US warehouse, ships to EU* Item #: K421259View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- propan-2-yl (Z)-3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]prop-2-enoate
- SMILES
- CC(C)OC(=O)C=CN1C=NC(=N1)C2=CC(=CC(=C2)OC)C(F)(F)F
- InChIKey
- NLNGWFLRRRYNIL-PLNGDYQASA-N
- InChI
- 1S/C16H16F3N3O3/c1-10(2)25-14(23)4-5-22-9-20-15(21-22)11-6-12(16(17,18)19)8-13(7-11)24-3/h4-10H,1-3H3/b5-4-
- Synonyms
- KPT185; KPT 185;(2Z)-3-[3-[3-Methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-Propenoic Acid 1-Methylethyl...
- KPT-276CAS: 1421919-75-6 Formula: C16H10F8N4O Molecular Weight: 426.2610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: K421564View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one
- SMILES
- C1C(CN1C(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)(F)F
- InChIKey
- JCHAWRDHMUSLMM-UPHRSURJSA-N
- InChI
- 1S/C16H10F8N4O/c17-14(18)6-27(7-14)12(29)1-2-28-8-25-13(26-28)9-3-10(15(19,20)21)5-11(4-9)16(22,23)24/h1-5,8H,6-7H2/b2-1-
- Synonyms
- 2-Propen-1-one, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-1-(3,3-difluoro-1-azetidinyl)-, (2Z)-;(Z...
- Verdinexor10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: V421474View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyridin-2-ylprop-2-enehydrazide
- SMILES
- C1=CC=NC(=C1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
- InChIKey
- OPAKEJZFFCECPN-XQRVVYSFSA-N
- InChI
- 1S/C18H12F6N6O/c19-17(20,21)12-7-11(8-13(9-12)18(22,23)24)16-26-10-30(29-16)6-4-15(31)28-27-14-3-1-2-5-25-14/h1-10H,(H,25,27)(H,28,31)/b6-4-
- Synonyms
- 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyridinyl)hydrazide, (2Z)- | KP...
- Verdinexor● In Stock — US warehouse, ships to EU* Item #: V347080View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyridin-2-ylprop-2-enehydrazide
- SMILES
- C1=CC=NC(=C1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
- InChIKey
- OPAKEJZFFCECPN-XQRVVYSFSA-N
- InChI
- 1S/C18H12F6N6O/c19-17(20,21)12-7-11(8-13(9-12)18(22,23)24)16-26-10-30(29-16)6-4-15(31)28-27-14-3-1-2-5-25-14/h1-10H,(H,25,27)(H,28,31)/b6-4-
- Synonyms
- 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyridinyl)hydrazide, (2Z)- | KP...
- Eltanexor Z-isomer◐ .Made to order · 8–12 wks Item #: E650555View ProductPricing & Pack Sizes
Technical Identifiers
Fast Shipping Same-day shipping on in-stock items
Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the CRM1 listing put together?
It draws on reported CRM1 annotations within Membrane Transporter/Ion Channel and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CRM1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CRM1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CRM1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CRM1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CRM1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CRM1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.