CXCR

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  1. AZ 10397767
    CAS: 333742-63-5 PubChem CID: 11858154 Formula: C15H14ClFN4O2S2 Molecular Weight: 400.88
    ◐ .Made to order · 8–12 wks Item #: A287373
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    IUPAC Name
    5-[(3-chloro-2-fluorophenyl)methylsulfanyl]-7-[[(2R)-1-hydroxypropan-2-yl]amino]-3H-[1,3]thiazolo[4,5-d]pyrimidin-2-one
    SMILES
    CC(CO)NC1=NC(=NC2=C1SC(=O)N2)SCC3=C(C(=CC=C3)Cl)F
    InChIKey
    KHTUORKUWBDRBX-SSDOTTSWSA-N
    InChI
    1S/C15H14ClFN4O2S2/c1-7(5-22)18-12-11-13(21-15(23)25-11)20-14(19-12)24-6-8-3-2-4-9(16)10(8)17/h2-4,7,22H,5-6H2,1H3,(H2,18,19,20,21,23)/t7-/m1/s1
    Synonyms
    5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one
  2. Arteether
    CAS: 75887-54-6 Formula: C17H28O5 Molecular Weight: 312.40
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● In Stock — US warehouse, ships to EU* Item #: A304569
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    IUPAC Name
    (1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
    SMILES
    CCOC1C(C2CCC(C3C24C(O1)OC(CC3)(OO4)C)C)C
    InChIKey
    NLYNIRQVMRLPIQ-XQLAAWPRSA-N
    InChI
    1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1
  3. Arteether
    CAS: 75887-54-6 EC Number: 112-004-0 Formula: C17H28O5 Molecular Weight: 312.40
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ◐ .Made to order · 8–12 wks Item #: A304568
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    IUPAC Name
    (1R,4S,5R,8S,9R,10S,12R,13R)-10-ethoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
    SMILES
    CCOC1C(C2CCC(C3C24C(O1)OC(CC3)(OO4)C)C)C
    InChIKey
    NLYNIRQVMRLPIQ-XQLAAWPRSA-N
    InChI
    1S/C17H28O5/c1-5-18-14-11(3)13-7-6-10(2)12-8-9-16(4)20-15(19-14)17(12,13)22-21-16/h10-15H,5-9H2,1-4H3/t10-,11-,12+,13+,14+,15-,16-,17-/m1/s1
    Synonyms
    β-Arteether | (+)-Arteether | (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyran...
  4. IT1t dihydrochloride
    CAS: 1092776-63-0 Formula: C21H34N4S2•2HCl Molecular Weight: 479.57
    ● In Stock — US warehouse, ships to EU* Item #: I287526
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    IUPAC Name
    (6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylcarbamimidothioate;dihydrochloride
    SMILES
    CC1(CN2C(=CSC2=N1)CSC(=NC3CCCCC3)NC4CCCCC4)C.Cl.Cl
    InChIKey
    HFXJOXOIINQOEB-UHFFFAOYSA-N
    InChI
    1S/C21H34N4S2.2ClH/c1-21(2)15-25-18(14-27-20(25)24-21)13-26-19(22-16-9-5-3-6-10-16)23-17-11-7-4-8-12-17;;/h14,16-17H,3-13,15H2,1-2H3,(H,22,23);2*1H
    Synonyms
    N,N'-Dicyclohexylcarbamimidothioic acid (5,6-dihydro-6,6-dimethylimidazo[2,1-b]thiazol-3-yl)methyl ester dihydrochlor...
  5. VUF 11207 fumarate
    CAS: 1785665-61-3 PubChem CID: 90488970 Formula: C27H35FN2O4.xC4H4O4 Molecular Weight: 586.65
    ● In Stock — US warehouse, ships to EU* Item #: V286581
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    IUPAC Name
    (E)-but-2-enedioic acid;N-[(E)-3-(2-fluorophenyl)-2-methylprop-2-enyl]-3,4,5-trimethoxy-N-[2-(1-methylpyrrolidin-2-yl)ethyl]benzamide
    SMILES
    CC(=CC1=CC=CC=C1F)CN(CCC2CCCN2C)C(=O)C3=CC(=C(C(=C3)OC)OC)OC.C(=CC(=O)O)C(=O)O
    InChIKey
    MTPOECCHJLVVGO-FDULSSLPSA-N
    InChI
    1S/C27H35FN2O4.C4H4O4/c1-19(15-20-9-6-7-11-23(20)28)18-30(14-12-22-10-8-13-29(22)2)27(31)21-16-24(32-3)26(34-5)25(17-21)33-4;5-3(6)1-2-4(7)8/h6-7,9,11show more
    Synonyms
    N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fum...
  6. SB 265610
    CAS: 211096-49-0 EC Number: 803-307-5 PubChem CID: 9841667 Formula: C14H9BrN6O Molecular Weight: 357.16
    ● In Stock — US warehouse, ships to EU* Item #: S288762
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    IUPAC Name
    1-(2-bromophenyl)-3-(7-cyano-2H-benzotriazol-4-yl)urea
    SMILES
    C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br
    InChIKey
    SEDUMQWZEOMXSO-UHFFFAOYSA-N
    InChI
    1S/C14H9BrN6O/c15-9-3-1-2-4-10(9)17-14(22)18-11-6-5-8(7-16)12-13(11)20-21-19-12/h1-6H,(H2,17,18,22)(H,19,20,21)
    Synonyms
    SB 265610; SB265610 | NCGC00242491-02 | Urea, N-(2-bromophenyl)-N'-(4-cyano-1H-benzotriazol-7-yl)- | Q27272851 | DTXS...
  7. FC 131
    CAS: 606968-52-9 Formula: C36H47N11O6 Molecular Weight: 729.8
    ◐ .Made to order · 8–12 wks Item #: F276123
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    IUPAC Name
    2-[3-[(2S,5S,8S,14R)-5-[3-(diaminomethylideneamino)propyl]-14-[(4-hydroxyphenyl)methyl]-8-(naphthalen-2-ylmethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-penshow more
    SMILES
    C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CC2=CC3=CC=CC=C3C=C2)CCCN=C(N)N)CCCN=C(N)N)CC4=CC=C(C=C4)O
    InChIKey
    MBXBICVKLVYNKD-XFTNXAEASA-N
    InChI
    1S/C36H47N11O6/c37-35(38)41-15-3-7-26-32(51)45-27(8-4-16-42-36(39)40)33(52)47-28(19-22-9-12-23-5-1-2-6-24(23)17-22)31(50)43-20-30(49)44-29(34(53)46-26show more
  8. Kynurenic acid, Agonist of GPR35
    CAS: 492-27-3 EC Number: 207-751-5 Formula: C10H7NO3 Molecular Weight: 189.17
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: K120012
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    IUPAC Name
    4-oxo-1H-quinoline-2-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
    InChIKey
    HCZHHEIFKROPDY-UHFFFAOYSA-N
    InChI
    1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
    Synonyms
    AMY18102 | BDBM81975 | Oprea1_032085 | Tox21_500716 | HCZHHEIFKROPDY-UHFFFAOYSA- | LP00716 | KYA | 4-Hydroxy-2-quinol...
  9. Kynurenic acid sodium salt
    CAS: 2439-02-3 PubChem CID: 52974250 Formula: C10H6NNaO3 Molecular Weight: 211.15
    ● In Stock — US warehouse, ships to EU* Item #: K274904
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    IUPAC Name
    sodium;4-oxo-1H-quinoline-2-carboxylate
    SMILES
    C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)[O-].[Na+]
    InChIKey
    RCAZGXKUQDXSSK-UHFFFAOYSA-M
    InChI
    1S/C10H7NO3.Na/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9;/h1-5H,(H,11,12)(H,13,14);/q;+1/p-1
    Synonyms
    4-Hydroxyquinoline-2-carboxylicacidsodiumsalt | Kynurenic acid sodium | sodium 4-oxo-1,4-dihydroquinoline-2-carboxylate
  10. SB 225002, Antagonist of CXCR2
    CAS: 182498-32-4 EC Number: 803-197-9 PubChem CID: 3854666 Formula: C13H10BrN3O4 Molecular Weight: 352.14
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S275393
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    IUPAC Name
    1-(2-bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea
    SMILES
    C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br
    InChIKey
    MQBZVUNNWUIPMK-UHFFFAOYSA-N
    InChI
    1S/C13H10BrN3O4/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17(20)21)7-12(11)18/h1-7,18H,(H2,15,16,19)
    Synonyms
    L000539 | J-011676 | Q27088712 | SCHEMBL1110610 | NCGC00167841-01 | BRD-K61323504-001-03-2 | N-(2-hydroxy-4-nitrophen...
  11. (±)-AMG 487
    CAS: 947536-03-0 Formula: C32H28F3N5O4 Molecular Weight: 603.59
    ◐ .Made to order · 8–12 wks Item #: A287645
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    IUPAC Name
    N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
    SMILES
    CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
    InChIKey
    WQTKNBPCJKRYPA-UHFFFAOYSA-N
    InChI
    1S/C32H28F3N5O4/c1-3-43-25-14-10-24(11-15-25)40-30(38-29-27(31(40)42)7-5-17-37-29)21(2)39(20-23-6-4-16-36-19-23)28(41)18-22-8-12-26(13-9-22)44-32(33,3show more
    Synonyms
    N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethox...
  12. 2-Mercapto-1-methylimidazole, Thyroid peroxidase inhibitor
    CAS: 60-56-0 EC Number: 200-482-4 Formula: C4H6N2S Molecular Weight: 114.17
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: M106466
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    IUPAC Name
    3-methyl-1H-imidazole-2-thione
    SMILES
    CN1C=CNC1=S
    InChIKey
    PMRYVIKBURPHAH-UHFFFAOYSA-N
    InChI
    1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
    Synonyms
    CAS-60-56-0 | 3-methyl-1H-imidazole-2-thione | AI3-60285 | Imidazole, 1-methyl-2-mercapto- | 1-methyl-2,3-dihydro-1H-...
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Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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