CXCR

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  1. Plerixafor, C-X-C chemokine receptor type 4 partial agonist
    CAS: 110078-46-1 EC Number: 842-163-8 Formula: C28H54N8 Molecular Weight: 502.78
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in Water
    ● In Stock — US warehouse, ships to EU* Item #: P420585
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    IUPAC Name
    1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane
    SMILES
    C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3
    InChIKey
    YIQPUIGJQJDJOS-UHFFFAOYSA-N
    InChI
    1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2
    Synonyms
    AMD 3100 | BDBM50035696 | DTXCID60817494 | FT-0673966 | GNA & AMD-3100 | SR-01000941593 | FT-0660392 | plerixaforum |...
  2. Reparixin, Interleukin-8 receptor B modulator
    CAS: 266359-83-5 EC Number: 691-864-3 PubChem CID: 9838712 Formula: C14H21NO3S Molecular Weight: 283.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R422939
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    IUPAC Name
    (2R)-2-[4-(2-methylpropyl)phenyl]-N-methylsulfonylpropanamide
    SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)NS(=O)(=O)C
    InChIKey
    KQDRVXQXKZXMHP-LLVKDONJSA-N
    InChI
    1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1
    Synonyms
    [D-Pen2,5]Enkephalin | Repertaxin;DF 1681Y | DTXSID6046509 | L-Arginyl-Glycyl-L-Aspartic acid | Bio1_000853 | HY-1525...
  3. Reparixin L-lysine salt
    CAS: 266359-93-7 PubChem CID: 9932389 Formula: C14H21NO3S.C6H14N2O2 Molecular Weight: 429.58
    ◐ .Made to order · 8–12 wks Item #: R287374
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    IUPAC Name
    (2S)-2,6-diaminohexanoic acid;(2R)-2-[4-(2-methylpropyl)phenyl]-N-methylsulfonylpropanamide
    SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)NS(=O)(=O)C.C(CCN)CC(C(=O)O)N
    InChIKey
    JEJFWWFZAQBZMJ-GVKMLHTLSA-N
    InChI
    1S/C14H21NO3S.C6H14N2O2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18;7-4-2-1-3-5(8)6(9)10/h5-8,10-11H,9H2,1-4H3,(H,15,16);5H,1-4,7-8H2,(H,9,10)show more
    Synonyms
    DTXSID80433019 | Reparixin lysine salt | Reparixin L-lysine salt | (2S)-2,6-diaminohexanoic acid;(2R)-2-[4-(2-methylp...
  4. SRT3109
    CAS: 1204707-71-0 PubChem CID: 44602493 Formula: C18H23F2N5O4S2 Molecular Weight: 475.53
    ◐ .Made to order · 8–12 wks Item #: S127704
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    IUPAC Name
    N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2R,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide
    SMILES
    CC(C(CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3
    InChIKey
    QVKPEMXUBULFBM-RISCZKNCSA-N
    InChI
    1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3show more
    Synonyms
    N-(2-(((2,3-Difluorophenyl)methyl)thio)-6-(((1R,2R)-2,3-dihydroxy-1-methylpropyl)amino)-4-pyrimidinyl)-1-azetidinesul...
  5. SX-682, Interleukin-8 receptors, CXCR1/CXCR2 inhibitor
    CAS: 1648843-04-2 PubChem CID: 90467234 Formula: C19H14BF4N3O4S Molecular Weight: 467.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S422044
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    IUPAC Name
    [2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
    SMILES
    B(C1=C(C=C(C=C1)OC(F)(F)F)CSC2=NC=C(C=N2)C(=O)NC3=CC=C(C=C3)F)(O)O
    InChIKey
    SDUDZBCEHIZMFZ-UHFFFAOYSA-N
    InChI
    1S/C19H14BF4N3O4S/c21-13-1-3-14(4-2-13)27-17(28)12-8-25-18(26-9-12)32-10-11-7-15(31-19(22,23)24)5-6-16(11)20(29)30/h1-9,29-30H,10H2,(H,27,28)
    Synonyms
    (2-(((5-((4-Fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronicacid | GTPL10165 | A...
  6. SX-682, Interleukin-8 receptors, CXCR1/CXCR2 inhibitor
    CAS: 1648843-04-2 PubChem CID: 90467234 Formula: C19H14BF4N3O4S Molecular Weight: 467.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: S414287
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    Technical Identifiers
    IUPAC Name
    [2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid
    SMILES
    B(C1=C(C=C(C=C1)OC(F)(F)F)CSC2=NC=C(C=N2)C(=O)NC3=CC=C(C=C3)F)(O)O
    InChIKey
    SDUDZBCEHIZMFZ-UHFFFAOYSA-N
    InChI
    1S/C19H14BF4N3O4S/c21-13-1-3-14(4-2-13)27-17(28)12-8-25-18(26-9-12)32-10-11-7-15(31-19(22,23)24)5-6-16(11)20(29)30/h1-9,29-30H,10H2,(H,27,28)
    Synonyms
    (2-(((5-((4-Fluorophenyl)carbamoyl)pyrimidin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronicacid | GTPL10165 | A...
  7. TAK-779
    CAS: 229005-80-5 PubChem CID: 183789 Formula: C33H39ClN2O2 Molecular Weight: 531.10
    ● In Stock — US warehouse, ships to EU* Item #: T412385
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    IUPAC Name
    dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride
    SMILES
    CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-]
    InChIKey
    VDALIBWXVQVFGZ-UHFFFAOYSA-N
    InChI
    1S/C33H38N2O2.ClH/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32;/h7-16,21-22,3show more
    Synonyms
    dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;...
  8. UNBS5162
    CAS: 956590-23-1 PubChem CID: 16048966 Formula: C17H18N4O3 Molecular Weight: 326.35
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: U414231
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    IUPAC Name
    [2-[2-(dimethylamino)ethyl]-1,3-dioxobenzo[de]isoquinolin-5-yl]urea
    SMILES
    CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)NC(=O)N
    InChIKey
    WCKZRLOUKYFJDY-UHFFFAOYSA-N
    InChI
    1S/C17H18N4O3/c1-20(2)6-7-21-15(22)12-5-3-4-10-8-11(19-17(18)24)9-13(14(10)12)16(21)23/h3-5,8-9H,6-7H2,1-2H3,(H3,18,19,24)
    Synonyms
    JY9JF7D78N | n-{2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1h-benzo[de]isoquinolin-5-yl}urea | AC-35979 | SCHEM...
  9. USL311
    CAS: 1373268-67-7 PubChem CID: 56961879 Formula: C24H34N6O Molecular Weight: 422.57
    ● In Stock — US warehouse, ships to EU* Item #: U413038
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    IUPAC Name
    6-[4-(1-propan-2-ylpiperidin-4-yl)-1,4-diazepan-1-yl]-N-pyridin-4-ylpyridine-2-carboxamide
    SMILES
    CC(C)N1CCC(CC1)N2CCCN(CC2)C3=CC=CC(=N3)C(=O)NC4=CC=NC=C4
    InChIKey
    XNUNVQKARNSSEO-UHFFFAOYSA-N
    InChI
    1S/C24H34N6O/c1-19(2)28-15-9-21(10-16-28)29-13-4-14-30(18-17-29)23-6-3-5-22(27-23)24(31)26-20-7-11-25-12-8-20/h3,5-8,11-12,19,21H,4,9-10,13-18H2,1-2H3show more
    Synonyms
    6-{4-[1-(propan-2-yl)piperidin-4-yl]-1,4-diazepan-1-yl}-N-(pyridin-4-yl)pyridine-2-carboxamide | BCP33234 | 1373268-6...
  10. WZ811
    CAS: 55778-02-4 EC Number: 694-750-1 PubChem CID: 11565518 Formula: C18H18N4 Molecular Weight: 290.36
    ● In Stock — US warehouse, ships to EU* Item #: W126879
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    Technical Identifiers
    IUPAC Name
    N-[[4-[(pyridin-2-ylamino)methyl]phenyl]methyl]pyridin-2-amine
    SMILES
    C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3
    InChIKey
    KBVFRXIGQQRMEF-UHFFFAOYSA-N
    InChI
    1S/C18H18N4/c1-3-11-19-17(5-1)21-13-15-7-9-16(10-8-15)14-22-18-6-2-4-12-20-18/h1-12H,13-14H2,(H,19,21)(H,20,22)
    Synonyms
    N,N''-(Benzene-1,4-diyldimethanediyl)dipyridin-2-amine | N,N''-di-2-pyridinyl-1,4-benzenedimethanamine | AS-16967 | N...
  11. Minecoside
    CAS: 51005-44-8 EC Number: 803-851-3 PubChem CID: 12002015 Formula: C25H30O13 Molecular Weight: 538.5
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: M463104
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    Technical Identifiers
    IUPAC Name
    [(1S,2S,4S,5S,6R,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yshow more
    SMILES
    COC1=C(C=C(C=C1)C=CC(=O)OC2C3C=COC(C3C4(C2O4)CO)OC5C(C(C(C(O5)CO)O)O)O)O
    InChIKey
    LRHHPZILMPIMIY-GGKKSNITSA-N
    InChI
    1S/C25H30O13/c1-33-14-4-2-11(8-13(14)28)3-5-16(29)36-21-12-6-7-34-23(17(12)25(10-27)22(21)38-25)37-24-20(32)19(31)18(30)15(9-26)35-24/h2-8,12,15,17-24show more
    Synonyms
    FS-9943 | Minecoside | Q27138142 | NCGC00180624-01 | NCGC00180624-03 | [(1aS,1bS,2S,5aR,6S,6aS)-1a-(hydroxymethyl)-2-...
  12. Decursin
    CAS: 5928-25-6 Formula: C19H20O5 Molecular Weight: 328.36
    ● In Stock — US warehouse, ships to EU* Item #: D418589
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    IUPAC Name
    [(3S)-2,2-dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] 3-methylbut-2-enoate
    SMILES
    CC(=CC(=O)OC1CC2=C(C=C3C(=C2)C=CC(=O)O3)OC1(C)C)C
    InChIKey
    CUKSFECWKQBVED-INIZCTEOSA-N
    InChI
    1S/C19H20O5/c1-11(2)7-18(21)23-16-9-13-8-12-5-6-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/t16-/m0/s1
    Synonyms
    2-Butenoic acid, 3-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo(1,2-b:5,4-b')dipyran-7-yl ester, (S)- | Ambap5...
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Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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