CXCR

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  1. Kynurenic acid, Agonist of GPR35
    CAS: 492-27-3 EC Number: 207-751-5 Formula: C10H7NO3 Molecular Weight: 189.17
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: K424259
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    IUPAC Name
    4-oxo-1H-quinoline-2-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O
    InChIKey
    HCZHHEIFKROPDY-UHFFFAOYSA-N
    InChI
    1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
    Synonyms
    AMY18102 | BDBM81975 | Oprea1_032085 | Tox21_500716 | HCZHHEIFKROPDY-UHFFFAOYSA- | LP00716 | KYA | 4-Hydroxy-2-quinol...
  2. MSX-127
    CAS: 6616-56-4 EC Number: 663-907-6 Formula: C16H24N2O4 Molecular Weight: 308.37
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M425330
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    IUPAC Name
    2,5-bis(morpholin-4-ylmethyl)benzene-1,4-diol
    SMILES
    C1COCCN1CC2=CC(=C(C=C2O)CN3CCOCC3)O
    InChIKey
    DGGCIZWVIVXHFR-UHFFFAOYSA-N
    InChI
    1S/C16H24N2O4/c19-15-10-14(12-18-3-7-22-8-4-18)16(20)9-13(15)11-17-1-5-21-6-2-17/h9-10,19-20H,1-8,11-12H2
    Synonyms
    MSX-127NSC23026 | A913780 | HY-103009 | Oprea1_481211 | 2,5-Bis(4-morpholinylmethyl)-1,4-benzenediol # | AE-848/31997...
  3. MSX-130
    CAS: 4051-59-6 Formula: C36H26N4 Molecular Weight: 514.62
    2mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: M423853
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    IUPAC Name
    2-[4-(4,5-diphenyl-1H-imidazol-2-yl)phenyl]-4,5-diphenyl-1H-imidazole
    SMILES
    C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C4=NC(=C(N4)C5=CC=CC=C5)C6=CC=CC=C6)C7=CC=CC=C7
    InChIKey
    MKRQQXYFSWSAIS-UHFFFAOYSA-N
    InChI
    1S/C36H26N4/c1-5-13-25(14-6-1)31-32(26-15-7-2-8-16-26)38-35(37-31)29-21-23-30(24-22-29)36-39-33(27-17-9-3-10-18-27)34(40-36)28-19-11-4-12-20-28/h1-24Hshow more
    Synonyms
    1H-​Imidazole,2,​2'-​(1,​4-​phenylene)​bis[4,​5-​diphenyl-
  4. MSX-122, C-X-C chemokine receptor type 4 antagonist
    CAS: 897657-95-3 Formula: C16H16N6 Molecular Weight: 292.34
    ● In Stock — US warehouse, ships to EU* Item #: M413551
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    IUPAC Name
    N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]pyrimidin-2-amine
    SMILES
    C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
    InChIKey
    PXZXYRKDDXKDTK-UHFFFAOYSA-N
    InChI
    1S/C16H16N6/c1-7-17-15(18-8-1)21-11-13-3-5-14(6-4-13)12-22-16-19-9-2-10-20-16/h1-10H,11-12H2,(H,17,18,21)(H,19,20,22)
    Synonyms
    Q27264343 | XKB65795 | UNII-69D634Q702 | BDBM194510 | DB12715 | N,N'-(1,4-phenylenebis(methylene))bis(pyrimidin-2-ami...
  5. MSX-127
    CAS: 6616-56-4 Formula: C16H24N2O4 Molecular Weight: 308.37
    ● In Stock — US warehouse, ships to EU* Item #: M412305
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    Technical Identifiers
    IUPAC Name
    2,5-bis(morpholin-4-ylmethyl)benzene-1,4-diol
    SMILES
    C1COCCN1CC2=CC(=C(C=C2O)CN3CCOCC3)O
    InChIKey
    DGGCIZWVIVXHFR-UHFFFAOYSA-N
    InChI
    1S/C16H24N2O4/c19-15-10-14(12-18-3-7-22-8-4-18)16(20)9-13(15)11-17-1-5-21-6-2-17/h9-10,19-20H,1-8,11-12H2
    Synonyms
    MSX-127NSC23026 | A913780 | HY-103009 | Oprea1_481211 | 2,5-Bis(4-morpholinylmethyl)-1,4-benzenediol # | AE-848/31997...
  6. MSX-130
    CAS: 4051-59-6 Formula: C36H26N4 Molecular Weight: 514.62
    ● In Stock — US warehouse, ships to EU* Item #: M412306
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    Technical Identifiers
    IUPAC Name
    2-[4-(4,5-diphenyl-1H-imidazol-2-yl)phenyl]-4,5-diphenyl-1H-imidazole
    SMILES
    C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C4=NC(=C(N4)C5=CC=CC=C5)C6=CC=CC=C6)C7=CC=CC=C7
    InChIKey
    MKRQQXYFSWSAIS-UHFFFAOYSA-N
    InChI
    1S/C36H26N4/c1-5-13-25(14-6-1)31-32(26-15-7-2-8-16-26)38-35(37-31)29-21-23-30(24-22-29)36-39-33(27-17-9-3-10-18-27)34(40-36)28-19-11-4-12-20-28/h1-24Hshow more
    Synonyms
    1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene
  7. MSX-122, C-X-C chemokine receptor type 4 antagonist
    CAS: 897657-95-3 Formula: C16H16N6 Molecular Weight: 292.34
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M426733
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    Technical Identifiers
    IUPAC Name
    N-[[4-[(pyrimidin-2-ylamino)methyl]phenyl]methyl]pyrimidin-2-amine
    SMILES
    C1=CN=C(N=C1)NCC2=CC=C(C=C2)CNC3=NC=CC=N3
    InChIKey
    PXZXYRKDDXKDTK-UHFFFAOYSA-N
    InChI
    1S/C16H16N6/c1-7-17-15(18-8-1)21-11-13-3-5-14(6-4-13)12-22-16-19-9-2-10-20-16/h1-10H,11-12H2,(H,17,18,21)(H,19,20,22)
    Synonyms
    Q27264343 | XKB65795 | UNII-69D634Q702 | BDBM194510 | DB12715 | N,N'-(1,4-phenylenebis(methylene))bis(pyrimidin-2-ami...
  8. Motixafortide (BL-8040)
    CAS: 664334-36-5 Formula: C97H144FN33O19S2 Molecular Weight: 2159.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    ◐ .Made to order · 8–12 wks Item #: M425344
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    IUPAC Name
    (3S,6S,9S,12S,15R,20R,23S,26S,29S,32S)-3,6-bis(4-aminobutyl)-N-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]-15-[[(2S)-2-[[(2S)-5-carbamimidamido-show more
    SMILES
    C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CC=C5C=show more
    InChIKey
    JJVZSYKFCOBILL-MKMRYRNGSA-N
    InChI
    1S/C97H144FN33O19S2/c98-60-33-31-58(32-34-60)78(135)119-65(19-8-42-113-93(104)105)79(136)121-68(21-10-44-115-95(108)109)83(140)126-73(51-56-25-30-57-1show more
    Synonyms
    CHEBI:145536 | L-ARGININAMIDE, N2-(4-FLUOROBENZOYL)-L-ARGINYL-L-ARGINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-CYSTEINYL-L-TYR...
  9. Navarixin (SCH-527123), Interleukin-8 receptor A antagonist
    CAS: 473727-83-2 Formula: C21H23N3O5 Molecular Weight: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N414035
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    IUPAC Name
    2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
    SMILES
    CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    InChIKey
    RXIUEIPPLAFSDF-CYBMUJFWSA-N
    InChI
    1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
    Synonyms
    Navarixin | SCH 527123,CAS:473727-83-2 | s8506 | (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-...
  10. Navarixin (SCH-527123), Interleukin-8 receptor A antagonist
    CAS: 473727-83-2 Formula: C21H23N3O5 Molecular Weight: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N424121
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    Technical Identifiers
    IUPAC Name
    2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzamide
    SMILES
    CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    InChIKey
    RXIUEIPPLAFSDF-CYBMUJFWSA-N
    InChI
    1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
    Synonyms
    MK-7123 | PS-291822Benzamide,2-​hydroxy-​N,​N-​dimethyl-​3-​[[2-​[[(1R)​-​1-​(5-​methyl-​2-​furanyl)​propyl]​amino]​-�...
  11. Nicotinamide N-Oxide
    CAS: 1986-81-8 EC Number: 217-859-4 Formula: C6H6N2O2 Molecular Weight: 138.12
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N422414
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    IUPAC Name
    1-oxidopyridin-1-ium-3-carboxamide
    SMILES
    C1=CC(=C[N+](=C1)[O-])C(=O)N
    InChIKey
    USSFUVKEHXDAPM-UHFFFAOYSA-N
    InChI
    1S/C6H6N2O2/c7-6(9)5-2-1-3-8(10)4-5/h1-4H,(H2,7,9)
    Synonyms
    3-Pyridinecarboxamide, 1-oxide | Nicotinamide N-oxide | InChI=1/C6H6N2O2/c7-6(9)5-2-1-3-8(10)4-5/h1-4H,(H2,7,9) | Nic...
  12. Plerixafor 8HCl (AMD3100 8HCl)
    CAS: 155148-31-5 EC Number: 828-184-5 PubChem CID: 65014 Formula: C28H54N8·8HCl Molecular Weight: 794.47
    10mM in Water
    ● In Stock — US warehouse, ships to EU* Item #: P421848
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    IUPAC Name
    1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;octahydrochloride
    SMILES
    C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl
    InChIKey
    UEUPDYPUTTUXLJ-UHFFFAOYSA-N
    InChI
    1S/C28H54N8.8ClH/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36;;;;;;;;/h5-8,29-34H,1-4,9show more
    Synonyms
    155148-31-5 (HCl) | Plerixafor hydrochloride | AMD3100 octahydrochloride hydrate | DTXSID20935148 | 1,1'-[1,4-Phenyle...
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Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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