CXCR

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  1. CXCR7 modulator 2
    CAS: 2227426-37-9 PubChem CID: 134694953 Formula: C29H42N6O3 Molecular Weight: 522.68
    ◐ .Made to order · 8–12 wks Item #: C650931
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    IUPAC Name
    (3S)-3-[4-(7-ethylimidazo[1,2-a]pyridin-8-yl)-1,4-diazepan-1-yl]-3-[1-[(1R,2S,4S)-7-oxabicyclo[2.2.1]heptane-2-carbonyl]piperidin-4-yl]propanamide
    SMILES
    CCC1=C(C2=NC=CN2C=C1)N3CCCN(CC3)C(CC(=O)N)C4CCN(CC4)C(=O)C5CC6CCC5O6
    InChIKey
    CERHKHQEGFSIHF-OJJQZRKESA-N
    InChI
    1S/C29H42N6O3/c1-2-20-6-12-34-15-9-31-28(34)27(20)33-11-3-10-32(16-17-33)24(19-26(30)36)21-7-13-35(14-8-21)29(37)23-18-22-4-5-25(23)38-22/h6,9,12,15,2show more
  2. CXCR2-IN-1
    CAS: 1873376-49-8 PubChem CID: 127020968 Formula: C19H20Cl2FN3O4S Molecular Weight: 476.35
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: C646999
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    IUPAC Name
    1-(2-chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(1-methylpiperidin-4-yl)sulfonylphenyl]urea
    SMILES
    CN1CCC(CC1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
    InChIKey
    BJYOBCUGMDKPBM-UHFFFAOYSA-N
    InChI
    1S/C19H20Cl2FN3O4S/c1-25-9-7-11(8-10-25)30(28,29)18-12(20)5-6-15(17(18)26)24-19(27)23-14-4-2-3-13(22)16(14)21/h2-6,11,26H,7-10H2,1H3,(H2,23,24,27)
  3. PS372424 hydrochloride
    CAS: 1596362-29-6 EC Number: 806-092-6 PubChem CID: 117064650 Formula: C33H45ClN6O4 Molecular Weight: 625.20
    ◐ .Made to order · 8–12 wks Item #: P647141
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    IUPAC Name
    (3S)-N-[(2S)-1-(cyclohexylmethylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-(4-oxo-4-phenylbutanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamshow more
    SMILES
    C1CCC(CC1)CNC(=O)C(CCCN=C(N)N)NC(=O)C2CC3=CC=CC=C3CN2C(=O)CCC(=O)C4=CC=CC=C4.Cl
    InChIKey
    XHGSJQNAEULTAR-DHBRAOIWSA-N
    InChI
    1S/C33H44N6O4.ClH/c34-33(35)36-19-9-16-27(31(42)37-21-23-10-3-1-4-11-23)38-32(43)28-20-25-14-7-8-15-26(25)22-39(28)30(41)18-17-29(40)24-12-5-2-6-13-24show more
    Synonyms
    (S)-N-((S)-1-((Cyclohexylmethyl)amino)-5-guanidino-1-oxopentan-2-yl)-2-(4-oxo-4-phenylbutanoyl)-1,2,3,4-tetrahydroiso...
  4. AMG 487 (S-enantiomer)
    CAS: 473720-30-8 Formula: C32H28F3N5O4 Molecular Weight: 603.59
    ◐ .Made to order · 8–12 wks Item #: A647540
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    IUPAC Name
    N-[(1S)-1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide
    SMILES
    CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F
    InChIKey
    WQTKNBPCJKRYPA-NRFANRHFSA-N
    InChI
    1S/C32H28F3N5O4/c1-3-43-25-14-10-24(11-15-25)40-30(38-29-27(31(40)42)7-5-17-37-29)21(2)39(20-23-6-4-16-36-19-23)28(41)18-22-8-12-26(13-9-22)44-32(33,3show more
  5. Mavorixafor trihydrochloride
    CAS: 2309699-17-8 PubChem CID: 78357868 Formula: C21H30Cl3N5 Molecular Weight: 458.86
    ◐ .Made to order · 8–12 wks Item #: M649127
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    IUPAC Name
    N'-(1H-benzimidazol-2-ylmethyl)-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine;trihydrochloride
    SMILES
    C1CC(C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl.Cl.Cl
    InChIKey
    FTHQTOSCZZCGHB-VLEZWVESSA-N
    InChI
    1S/C21H27N5.3ClH/c22-12-3-4-14-26(15-20-24-17-9-1-2-10-18(17)25-20)19-11-5-7-16-8-6-13-23-21(16)19;;;/h1-2,6,8-10,13,19H,3-5,7,11-12,14-15,22H2,(H,24,show more
  6. Burixafor hydrobromide
    CAS: 1191450-19-7 PubChem CID: 154575080 Formula: C27H51N8O3P.5/2HBr Molecular Weight: 769.01
    ◐ .Made to order · 8–12 wks Item #: B649161
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    IUPAC Name
    2-[4-[6-amino-2-[[4-[[3-(cyclohexylamino)propylamino]methyl]cyclohexyl]methylamino]pyrimidin-4-yl]piperazin-1-yl]ethylphosphonic acid;hydrobromide
    SMILES
    C1CCC(CC1)NCCCNCC2CCC(CC2)CNC3=NC(=CC(=N3)N4CCN(CC4)CCP(=O)(O)O)N.Br
    InChIKey
    ZXUVXYNBMUFEMK-UHFFFAOYSA-N
    InChI
    1S/C27H51N8O3P.BrH/c28-25-19-26(35-15-13-34(14-16-35)17-18-39(36,37)38)33-27(32-25)31-21-23-9-7-22(8-10-23)20-29-11-4-12-30-24-5-2-1-3-6-24;/h19,22-24show more
  7. SCH 563705
    CAS: 473728-58-4 PubChem CID: 10310100 Formula: C23H27N3O5 Molecular Weight: 425.48
    ◐ .Made to order · 8–12 wks Item #: S649455
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    IUPAC Name
    3-[[3,4-dioxo-2-[[(1R)-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
    SMILES
    CCC(C1=CC(=CO1)C(C)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C
    InChIKey
    DGKQQEVYYPCMNE-OAHLLOKOSA-N
    InChI
    1S/C23H27N3O5/c1-6-15(17-10-13(11-31-17)12(2)3)24-18-19(22(29)21(18)28)25-16-9-7-8-14(20(16)27)23(30)26(4)5/h7-12,15,24-25,27H,6H2,1-5H3/t15-/m1/s1
    Synonyms
    MS-27493 | AKOS016009722 | CC(C1=COC([C@H](NC2=C(C(C2=O)=O)NC3=CC=CC(C(N(C)C)=O)=C3O)CC)=C1)C | SCH-563705 | NCGC0037...
  8. Ladarixin sodium
    CAS: 865625-56-5 EC Number: 691-863-8 PubChem CID: 23709380 Formula: C11H11F3NNaO6S2 Molecular Weight: 397.32
    ◐ .Made to order · 8–12 wks Item #: L651287
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    IUPAC Name
    sodium;methylsulfonyl-[(2R)-2-[4-(trifluoromethylsulfonyloxy)phenyl]propanoyl]azanide
    SMILES
    CC(C1=CC=C(C=C1)OS(=O)(=O)C(F)(F)F)C(=O)[N-]S(=O)(=O)C.[Na+]
    InChIKey
    QICAUCDBOAKDNS-OGFXRTJISA-M
    InChI
    1S/C11H12F3NO6S2.Na/c1-7(10(16)15-22(2,17)18)8-3-5-9(6-4-8)21-23(19,20)11(12,13)14;/h3-7H,1-2H3,(H,15,16);/q;+1/p-1/t7-;/m1./s1
    Synonyms
    Ladarixin (sodium) | DF 2156A | SODIUM METHANESULFONYL[(2R)-2-[4-(TRIFLUOROMETHANESULFONYLOXY)PHENYL]PROPANOYL]AZANID...
  9. Balixafortide TFA
    CAS: 1051366-32-5(free base) Formula: C84H118N24O21S2(free base) Molecular Weight: 1864.11(free base)
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: B658810
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    Technical Identifiers
    Synonyms
    POL6326 TFA
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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