CXCR

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  1. BVT173187, Antagonist of FPR1
    CAS: 1374984-75-4 PubChem CID: 73755160
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: B608261
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    IUPAC Name
    3,5-dichloro-N-(2-chloro-5-methylphenyl)-2-hydroxybenzamide
    SMILES
    Cc1ccc(c(c1)NC(=O)c1cc(Cl)cc(c1O)Cl)Cl
    InChIKey
    UCOQCHLODZCXRH-UHFFFAOYSA-N
    InChI
    1S/C14H10Cl3NO2/c1-7-2-3-10(16)12(4-7)18-14(20)9-5-8(15)6-11(17)13(9)19/h2-6,19H,1H3,(H,18,20)
    Synonyms
    BVT 173187
  2. Elubrixin, Interleukin-8 receptor B antagonist
    CAS: 688763-64-6 EC Number: 629-900-7 PubChem CID: 10479502 Formula: C17H17Cl2FN4O4S Molecular Weight: 463.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: E610106
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    IUPAC Name
    1-(2-chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea
    SMILES
    C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
    InChIKey
    YQYFEGTYCUQBEI-UHFFFAOYSA-N
    InChI
    1S/C17H17Cl2FN4O4S/c18-10-4-5-13(23-17(26)22-12-3-1-2-11(20)14(12)19)15(25)16(10)29(27,28)24-8-6-21-7-9-24/h1-5,21,25H,6-9H2,(H2,22,23,26)
    Synonyms
    1-(4-chloro-2-hydroxy-3-(piperazin-1-ylsulfonyl)phenyl)-3-(2-chloro-3-fluorophenyl)urea | SB-656933
  3. TC14012, Agonist of ACKR3
    CAS: 368874-34-4 PubChem CID: 16130651 Formula: C90H140N34O19S2 Molecular Weight: 2066.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp175267
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    IUPAC Name
    (3R,6S,9S,12S,15R,20R,23S,26S,29S,32S)-6-(4-aminobutyl)-N-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbshow more
    SMILES
    C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCNC(=O)N)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CCshow more
    InChIKey
    SGDDHDBBOJNZKY-LNDHEDFZSA-N
    InChI
    1S/C90H140N34O19S2/c91-34-4-3-16-58-74(131)118-63(22-11-41-111-90(104)143)83(140)124-42-12-23-69(124)82(139)121-65(45-50-27-32-55(126)33-28-50)78(135)show more
    Synonyms
    TC 14012 | TC-14012
  4. T140, Antagonist of CXCR4
    CAS: 229030-20-0 PubChem CID: 16130395
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp175253
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    IUPAC Name
    (2S)-2-[[(3R,6S,9S,12S,15R,20R,23S,26S,29S,32S)-3,6-bis(4-aminobutyl)-15-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-5-carbamimshow more
    SMILES
    C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCCN)CCCCN)CCCNC(=N)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CC=C5C=show more
    InChIKey
    IMOHHNXUCDZLKM-ADZSTZGASA-N
    InChI
    1S/C90H141N33O18S2/c91-35-5-3-17-58-74(129)116-63(18-4-6-36-92)83(138)123-43-13-24-70(123)82(137)120-66(46-51-28-33-56(125)34-29-51)78(133)115-61(21-1show more
    Synonyms
    GTPL853 | Q27088913 | HY-P4810 | DTXSID80177446 | T 140 | H-Arg-Ala-Nal-Cys-Tyr-Arg-Lys-DLys-Pro-Tyr-Arg-Cit-Cys-Arg-...
  5. motixafortide, Antagonist of CXCR4
    CAS: 664334-36-5 Formula: C97H144FN33O19S2 Molecular Weight: 2159.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp174550
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    Technical Identifiers
    IUPAC Name
    (3S,6S,9S,12S,15R,20R,23S,26S,29S,32S)-3,6-bis(4-aminobutyl)-N-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]-15-[[(2S)-2-[[(2S)-5-carbamimidamido-show more
    SMILES
    C1CC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)C(CC4=CC5=CC=CC=C5C=show more
    InChIKey
    JJVZSYKFCOBILL-MKMRYRNGSA-N
    InChI
    1S/C97H144FN33O19S2/c98-60-33-31-58(32-34-60)78(135)119-65(19-8-42-113-93(104)105)79(136)121-68(21-10-44-115-95(108)109)83(140)126-73(51-56-25-30-57-1show more
    Synonyms
    CHEBI:145536 | L-ARGININAMIDE, N2-(4-FLUOROBENZOYL)-L-ARGINYL-L-ARGINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-CYSTEINYL-L-TYR...
  6. vimnerixin
    CAS: 1418112-77-2 PubChem CID: 71209600
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: V614748
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    IUPAC Name
    N-[6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy-2-[(4-fluorophenyl)methylsulfanyl]pyrimidin-4-yl]-3-methylazetidine-1-sulfonamide
    SMILES
    CC1CN(C1)S(=O)(=O)Nc1cc(nc(n1)SCc1ccc(cc1)F)O[C@H](C)[C@H](CO)O
    InChIKey
    UCCNQCNIPRKLRP-CJNGLKHVSA-N
    InChI
    1S/C19H25FN4O5S2/c1-12-8-24(9-12)31(27,28)23-17-7-18(29-13(2)16(26)10-25)22-19(21-17)30-11-14-3-5-15(20)6-4-14/h3-7,12-13,16,25-26H,8-11H2,1-2H3,(H,21show more
    Synonyms
    N-[6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy-2-[(4-fluorophenyl)methylsulfanyl]pyrimidin-4-yl]-3-methylazetidine-1-sulfo...
  7. pCXCL8-1aa
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp174729
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    Technical Identifiers
    SMILES
    NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CC(=O)N)CCC(=O)O)C)CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]show more
    InChIKey
    WAKZDRBORDWUSJ-NXCVNOGKSA-N
    InChI
    1S/C53H88N16O17/c1-28(2)24-36(66-50(83)37(25-30-12-5-4-6-13-30)67-47(80)32(14-7-9-21-54)63-44(77)31(56)17-19-41(72)73)49(82)65-33(15-8-10-22-55)46(79)show more
  8. Ulocuplumab (anti-CXCR4), INHIBITOR of C-X-C chemokine receptor type 4 inhibitor
    CAS: 1375830-34-4
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab175993
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CXCR4
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human, Mouse
    Isotype
    Human IgG4SP
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    CXCR-4 | CXC-R4 | FB22 | Fusin | HM89 | LAP-3 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor ...
  9. Eldelumab (anti-CXCL10), INHIBITOR of C-X-C motif chemokine 10 inhibitor
    CAS: 946414-98-8
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170882
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CXCL10
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human, Rhesus monkey
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    Interferon gamma induced factor MOB1, mouse, homolog of antibody | Interferon gamma induced protein 10 antibody | 10 ...
  10. Quetmolimab (anti-CX3CL1), INHIBITOR of Fractalkine inhibitor
    CAS: 2084037-83-0
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab177929
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CX3CL1
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human
    Isotype
    Human IgG2
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    CX3C membrane-anchored chemokine | C-X3-C motif chemokine 1 | Neurotactin | Small-inducible cytokine D1
  11. NBI-74330
    CAS: 855527-92-3 Formula: C32H27F4N5O3 Molecular Weight: 605.58
    ◐ .Made to order · 8–12 wks Item #: N646511
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    Technical Identifiers
    IUPAC Name
    N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide
    SMILES
    CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC(=C(C=C5)F)C(F)(F)F
    InChIKey
    XMRGQUDUVGRCBS-UHFFFAOYSA-N
    InChI
    1S/C32H27F4N5O3/c1-3-44-24-11-9-23(10-12-24)41-30(39-29-25(31(41)43)7-5-15-38-29)20(2)40(19-22-6-4-14-37-18-22)28(42)17-21-8-13-27(33)26(16-21)32(34,3show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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