CXCR

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  1. Ladarixin, Interleukin-8 receptor B modulator
    CAS: 849776-05-2 PubChem CID: 11372270 Formula: C11H12F3NO6S2 Molecular Weight: 375.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: L647680
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    Technical Identifiers
    IUPAC Name
    [4-[(2R)-1-(methanesulfonamido)-1-oxopropan-2-yl]phenyl] trifluoromethanesulfonate
    SMILES
    C[C@H](C1=CC=C(C=C1)OS(=O)(=O)C(F)(F)F)C(=O)NS(=O)(=O)C
    InChIKey
    DDLPYOCJHQSVSZ-SSDOTTSWSA-N
    InChI
    1S/C11H12F3NO6S2/c1-7(10(16)15-22(2,17)18)8-3-5-9(6-4-8)21-23(19,20)11(12,13)14/h3-7H,1-2H3,(H,15,16)/t7-/m1/s1
    Synonyms
    Ladarixin | Q27276351 | CHEMBL189475 | 849776-05-2 (free) | DEH7Q6472O | AC6925 | LADARIXIN [WHO-DD] | A857904 | Lada...
  2. CXCR2-IN-2
    CAS: 1838123-21-9 PubChem CID: 100951623 Formula: C18H23ClN2O5S Molecular Weight: 414.90
    ◐ .Made to order · 8–12 wks Item #: C648383
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    IUPAC Name
    1-[4-chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea
    SMILES
    CC1=CCCC1NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)C3(CCOC3)C)O
    InChIKey
    DNXKACKCTLURQN-ACJLOTCBSA-N
    InChI
    1S/C18H23ClN2O5S/c1-11-4-3-5-13(11)20-17(23)21-14-7-6-12(19)16(15(14)22)27(24,25)18(2)8-9-26-10-18/h4,6-7,13,22H,3,5,8-10H2,1-2H3,(H2,20,21,23)/t13-,1show more
  3. AZD8797
    CAS: 911715-90-7 PubChem CID: 11965767 Formula: C19H25N5OS2 Molecular Weight: 403.56
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A649378
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    Technical Identifiers
    IUPAC Name
    (2R)-2-[[2-amino-5-[(1S)-1-phenylethyl]sulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
    SMILES
    CC(C)CC(CO)NC1=NC(=NC2=C1SC(=N2)N)SC(C)C3=CC=CC=C3
    InChIKey
    ZMQSLMZOWVGBSM-GXTWGEPZSA-N
    InChI
    1S/C19H25N5OS2/c1-11(2)9-14(10-25)21-16-15-17(22-18(20)27-15)24-19(23-16)26-12(3)13-7-5-4-6-8-13/h4-8,11-12,14,25H,9-10H2,1-3H3,(H3,20,21,22,23,24)/t1show more
    Synonyms
    (R)-2-((2-Amino-5-(((S)-1-phenylethyl)thio)thiazolo[4,5-d]pyrimidin-7-yl)amino)-4-methylpentan-1-ol | (2R)-2-[[2-amin...
  4. SCH 546738
    CAS: 906805-42-3 PubChem CID: 11995774 Formula: C23H31Cl2N7O Molecular Weight: 492.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: S649861
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    Technical Identifiers
    IUPAC Name
    3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide
    SMILES
    CCC1CN(CCN1C2CCN(CC2)CC3=CC=C(C=C3)Cl)C4=NC(=C(N=C4Cl)C(=O)N)N
    InChIKey
    UYDYJFWSPRQEAX-KRWDZBQOSA-N
    InChI
    1S/C23H31Cl2N7O/c1-2-17-14-31(23-20(25)28-19(22(27)33)21(26)29-23)11-12-32(17)18-7-9-30(10-8-18)13-15-3-5-16(24)6-4-15/h3-6,17-18H,2,7-14H2,1H3,(H2,26show more
    Synonyms
    HY-10017 | AKOS016005318 | 3-Amino-6-chloro-5-((3S)-4-(1-((4-chlorophenyl)methyl)piperidin-4-yl)-3-ethylpiperazin-1-y...
  5. Elubrixin tosylate
    CAS: 960495-43-6 EC Number: 629-901-2 PubChem CID: 23634419 Formula: C24H25Cl2FN4O7S2 Molecular Weight: 635.51
    ◐ .Made to order · 8–12 wks Item #: E649974
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    Technical Identifiers
    IUPAC Name
    1-(2-chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea;4-methylbenzenesulfonic acid
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
    InChIKey
    CJAUWWGOABMMJX-UHFFFAOYSA-N
    InChI
    1S/C17H17Cl2FN4O4S.C7H8O3S/c18-10-4-5-13(23-17(26)22-12-3-1-2-11(20)14(12)19)15(25)16(10)29(27,28)24-8-6-21-7-9-24;1-6-2-4-7(5-3-6)11(8,9)10/h1-5,21,2show more
    Synonyms
    D10420 | DTXSID60242106 | Elubrixin tosylate (USAN) | MS-30886 | SB-656933-AAA | 13FVR7WD4P | ELUBRIXIN TOSILATE [WHO...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the CXCR listing put together?
It draws on reported CXCR annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CXCR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CXCR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CXCR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CXCR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CXCR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CXCR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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