DYRK

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  1. MU1210
    CAS: 2275601-87-9 PubChem CID: 155891794
    ◐ .Made to order · 8–12 wks Item #: M1425991
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    IUPAC Name
    5-(1-methylpyrazol-4-yl)-3-(3-pyridin-4-ylphenyl)furo[3,2-b]pyridine
    SMILES
    CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5
    InChIKey
    HEAGNKNMQVIVMM-UHFFFAOYSA-N
    InChI
    1S/C22H16N4O/c1-26-13-18(12-24-26)20-5-6-21-22(25-20)19(14-27-21)17-4-2-3-16(11-17)15-7-9-23-10-8-15/h2-14H,1H3
  2. AZ-Dyrk1B-33
    CAS: 1679330-37-0 Formula: C19H16N4 Molecular Weight: 300.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: A1495074
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  3. DYRKs-IN-1 hydrochloride
    CAS: 1386980-55-7 Formula: C30H31Cl2N7O4 Molecular Weight: 624.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: D1495923
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  4. Dyrk1A-IN-3
    CAS: 2493976-27-3 Formula: C18H16N6 Molecular Weight: 316.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: D1497306
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  5. Dyrk1A-IN-5
    CAS: 1685235-41-9 Formula: C16H9IN2O2 Molecular Weight: 388.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: D1497267
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  6. GNF2133
    CAS: 2561414-56-8 Formula: C24H30N6O2 Molecular Weight: 434.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: G1496953
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  7. INDY
    CAS: 1169755-45-6 Formula: C12H13NO2S Molecular Weight: 235.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: I1494113
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the DYRK listing put together?
It draws on reported DYRK annotations within Protein Tyrosine Kinase/RTK and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a DYRK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the DYRK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for DYRK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For DYRK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the DYRK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of DYRK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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