DYRK

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  1. GSK-626616
    CAS: 1025821-33-3 EC Number: 852-159-8 Formula: C18H10Cl2N4OS Molecular Weight: 401.27
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: G1493793
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  2. ON 108600
    CAS: 1585246-23-6 Formula: C22H14Cl2N2O6S2 Molecular Weight: 537.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: O1498228
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  3. LDN-209929 dihydrochloride
    CAS: 1784281-97-5 PubChem CID: 90488975 Formula: C17H17ClN2OS.2HCl Molecular Weight: 405.77
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: L1494423
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  4. LDN-192960
    CAS: 184582-62-5 Formula: C18H20N2O2S Molecular Weight: 328.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: L1496322
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  5. RO5454948
    CAS: 1386979-55-0 PubChem CID: 57523919 Formula: C23H17Cl2N5O4 Molecular Weight: 498.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: R1495872
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the DYRK listing put together?
It draws on reported DYRK annotations within Protein Tyrosine Kinase/RTK and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a DYRK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the DYRK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for DYRK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For DYRK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the DYRK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of DYRK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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