E1/E2/E3 Enzyme

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  1. brigimadlin
    CAS: 2095116-40-6 PubChem CID: 129264140 Formula: C31H25Cl2FN4O3 Molecular Weight: 591.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: B608217
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    SMILES
    [H][C@]12CC3=C4C=CC(C(O)=O)=C(C)C4=NN3[C@@]1([H])[C@]([H])(C5=CC=CC(Cl)=C5F)[C@@]6(N2CC7CC7)C(=O)NC8=CC(Cl)=CC=C68
    InChIKey
    AMTXDBGKYPDTTA-SJVQGLCSSA-N
    InChI
    1S/C31H25Cl2FN4O3/c1-14-17(29(39)40)8-9-18-23-12-24-28(38(23)36-27(14)18)25(19-3-2-4-21(33)26(19)34)31(37(24)13-15-5-6-15)20-10-7-16(32)11-22(20)35-30show more
    Synonyms
    9A934ZAN94 | GTPL12627 | EX-A7776 | Brigimadlin | US10717742, Example Ia-34 | HY-152859 | example Ia-34 [WO2017060431...
  2. CTX1
    CAS: 501935-96-2 EC Number: 110-728-1 PubChem CID: 435038 Formula: C14H10N4 Molecular Weight: 234.26
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ◐ .Made to order · 8–12 wks Item #: C646180
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    IUPAC Name
    3,6-diaminoacridine-9-carbonitrile
    SMILES
    C1=CC2=C(C=C1N)N=C3C=C(C=CC3=C2C#N)N
    InChIKey
    PUMGFEMNXBLDKD-UHFFFAOYSA-N
    InChI
    1S/C14H10N4/c15-7-12-10-3-1-8(16)5-13(10)18-14-6-9(17)2-4-11(12)14/h1-6H,16-17H2
    Synonyms
    3,6-Diaminoacridine-9-carbonitrile
  3. p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
    CAS: 2070009-27-5 Formula: C40H51Cl4N5O4 Molecular Weight: 807.68
    ◐ .Made to order · 8–12 wks Item #: P646528
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    SMILES
    O=C(N1CCN(CC(N2CCOCC2)=O)CC1)N3[C@](C)(C4=CC=C(Cl)C=C4)[C@](C)(C5=CC=C(Cl)C=C5)N=C3C6=CC=C(C(C)(C)C)C=C6OCC.Cl.Cl
  4. MI-773
    CAS: 1303607-07-9 Formula: C29H34Cl2FN3O3 Molecular Weight: 562.5
    ◐ .Made to order · 8–12 wks Item #: M647063
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    IUPAC Name
    (2'R,3S,3'S,5'R)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-N-(4-hydroxycyclohexyl)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboshow more
    SMILES
    CC(C)(C)CC1C2(C(C(N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O
    InChIKey
    IDKAKZRYYDCJDU-YJRDPZTCSA-N
    InChI
    1S/C29H34Cl2FN3O3/c1-28(2,3)14-22-29(19-12-7-15(30)13-21(19)34-27(29)38)23(18-5-4-6-20(31)24(18)32)25(35-22)26(37)33-16-8-10-17(36)11-9-16/h4-7,12-13,show more
  5. BI8622
    CAS: 1875036-74-0 PubChem CID: 138377590 Formula: C25H26N6O Molecular Weight: 426.51
    ◐ .Made to order · 8–12 wks Item #: B647461
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    IUPAC Name
    N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenylpiperidin-1-yl)-5-methylpyrimidine-4-carboxamide
    SMILES
    CC1=C(N=CN=C1N2CCC(CC2)(C#N)C3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)CN
    InChIKey
    IJHAXMJRQQTBPL-UHFFFAOYSA-N
    InChI
    1S/C25H26N6O/c1-18-22(24(32)30-21-9-7-19(15-26)8-10-21)28-17-29-23(18)31-13-11-25(16-27,12-14-31)20-5-3-2-4-6-20/h2-10,17H,11-15,26H2,1H3,(H,30,32)
  6. Alrizomadlin, Tumour suppressor p53/oncoprotein Mdm2 inhibitor
    CAS: 1818393-16-6 PubChem CID: 91972012 Formula: C34H38Cl2FN3O4 Molecular Weight: 642.59
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A647965
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    SMILES
    CCN1C(C(C2(C13CCCCC3)C4=C(C=C(C=C4)Cl)NC2=O)C5=C(C(=CC=C5)Cl)F)C(=O)NC67CCC(CC6)(CC7)C(=O)O
    InChIKey
    YJCZPJQGFSSFOL-MNZPCBJKSA-N
    InChI
    1S/C34H38Cl2FN3O4/c1-2-40-27(28(41)39-32-16-13-31(14-17-32,15-18-32)30(43)44)25(21-7-6-8-23(36)26(21)37)34(33(40)11-4-3-5-12-33)22-10-9-20(35)19-24(22show more
    Synonyms
    15QAU0SI9J | AA-115 | 1818393-16-6 | 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro...
  7. DI-591
    CAS: 2245887-38-9 PubChem CID: 131750123 Formula: C31H47N5O4S Molecular Weight: 585.80
    ◐ .Made to order · 8–12 wks Item #: D648484
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    IUPAC Name
    (2S)-N-[(1S)-1-cyclohexyl-2-(3-morpholin-4-ylpropanoylamino)ethyl]-2-(propanoylamino)-3-(6-propan-2-yl-1,3-benzothiazol-2-yl)propanamide
    SMILES
    CCC(=O)NC(CC1=NC2=C(S1)C=C(C=C2)C(C)C)C(=O)NC(CNC(=O)CCN3CCOCC3)C4CCCCC4
    InChIKey
    CNJKDQGPBAWNRY-IZZNHLLZSA-N
    InChI
    1S/C31H47N5O4S/c1-4-28(37)33-25(19-30-34-24-11-10-23(21(2)3)18-27(24)41-30)31(39)35-26(22-8-6-5-7-9-22)20-32-29(38)12-13-36-14-16-40-17-15-36/h10-11,1show more
  8. RO-5963
    CAS: 1416663-77-8 PubChem CID: 136683438 Formula: C24H21ClF2N4O5 Molecular Weight: 518.90
    ◐ .Made to order · 8–12 wks Item #: R646304
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    IUPAC Name
    2-[5-[(6-chloro-7-methylindol-3-ylidene)methyl]-4-hydroxy-2-oxo-1H-imidazol-3-yl]-2-(3,4-difluorophenyl)-N-(1,3-dihydroxypropan-2-yl)acetamide
    SMILES
    CC1=C(C=CC2=C1N=CC2=CC3=C(N(C(=O)N3)C(C4=CC(=C(C=C4)F)F)C(=O)NC(CO)CO)O)Cl
    InChIKey
    IFYMUYSGUSHEPI-UHFFFAOYSA-N
    InChI
    1S/C24H21ClF2N4O5/c1-11-16(25)4-3-15-13(8-28-20(11)15)7-19-23(35)31(24(36)30-19)21(22(34)29-14(9-32)10-33)12-2-5-17(26)18(27)6-12/h2-8,14,21,32-33,35Hshow more
  9. MD-224
    CAS: 2136247-12-4 PubChem CID: 131986956 Formula: C48H43Cl2FN6O6 Molecular Weight: 889.80
    ◐ .Made to order · 8–12 wks Item #: M649182
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    Technical Identifiers
    SMILES
    C1CCC2(CC1)C3(C(C(N2)C(=O)NC4=CC=C(C=C4)C(=O)NCCCC#CC5=C6CN(C(=O)C6=CC=C5)C7CCC(=O)NC7=O)C8=C(C(=CC=C8)Cl)F)C9=C(C=C(C=C9)Cl)NC3=O
    InChIKey
    ZLGNYFOIDAVMHY-MPKOGUQCSA-N
    InChI
    1S/C48H43Cl2FN6O6/c49-29-16-19-34-36(25-29)54-46(63)48(34)39(32-12-8-13-35(50)40(32)51)41(56-47(48)22-4-2-5-23-47)44(61)53-30-17-14-28(15-18-30)42(59)show more
  10. LS-102
    CAS: 1456891-34-1 PubChem CID: 118518043 Formula: C24H36N8O Molecular Weight: 452.6
    ◐ .Made to order · 8–12 wks Item #: L649461
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    IUPAC Name
    6-N-(1,3-benzoxazol-6-yl)-4-N-[(1S)-1-cyclohexylethyl]-2-N-ethyl-2-N-[2-(ethylamino)ethyl]-1,3,5-triazine-2,4,6-triamine
    SMILES
    CCNCCN(CC)C1=NC(=NC(=N1)NC(C)C2CCCCC2)NC3=CC4=C(C=C3)N=CO4
    InChIKey
    DEDHMXBDEJSZFE-KRWDZBQOSA-N
    InChI
    1S/C24H36N8O/c1-4-25-13-14-32(5-2)24-30-22(27-17(3)18-9-7-6-8-10-18)29-23(31-24)28-19-11-12-20-21(15-19)33-16-26-20/h11-12,15-18,25H,4-10,13-14H2,1-3Hshow more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under E1/E2/E3 Enzyme?
This listing collects compounds associated with E1/E2/E3 Enzyme within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for E1/E2/E3 Enzyme?
Consider the reported potency of each E1/E2/E3 Enzyme compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for E1/E2/E3 Enzyme compounds?
Each E1/E2/E3 Enzyme product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search E1/E2/E3 Enzyme compounds by activity or structure?
Yes. Filter the E1/E2/E3 Enzyme listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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