E1/E2/E3 Enzyme

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  1. MX69
    CAS: 1005264-47-0 EC Number: 890-378-0 Formula: C27H26N2O4S Molecular Weight: 474.57
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M420280
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    Technical Identifiers
    IUPAC Name
    4-[8-[(3,4-dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid
    SMILES
    CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC3=C(C=C2)NC(C4C3C=CC4)C5=CC=C(C=C5)C(=O)O)C
    InChIKey
    XCBONKHCCRJMNW-UHFFFAOYSA-N
    InChI
    1S/C27H26N2O4S/c1-16-6-11-20(14-17(16)2)29-34(32,33)21-12-13-25-24(15-21)22-4-3-5-23(22)26(28-25)18-7-9-19(10-8-18)27(30)31/h3-4,6-15,22-23,26,28-29H,show more
    Synonyms
    AC-35792 | STL199512 | MX69 | MX-69 | BS-14153 | BCP19296 | EX-A2460 | C71033 | HY-100892 | 1005264-47-0 | s8403 | 4-...
  2. MX69
    CAS: 1005264-47-0 Formula: C27H26N2O4S Molecular Weight: 474.57
    ● In Stock — US warehouse, ships to EU* Item #: M414002
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    Technical Identifiers
    IUPAC Name
    4-[8-[(3,4-dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid
    SMILES
    CC1=C(C=C(C=C1)NS(=O)(=O)C2=CC3=C(C=C2)NC(C4C3C=CC4)C5=CC=C(C=C5)C(=O)O)C
    InChIKey
    XCBONKHCCRJMNW-UHFFFAOYSA-N
    InChI
    1S/C27H26N2O4S/c1-16-6-11-20(14-17(16)2)29-34(32,33)21-12-13-25-24(15-21)22-4-3-5-23(22)26(28-25)18-7-9-19(10-8-18)27(30)31/h3-4,6-15,22-23,26,28-29H,show more
    Synonyms
    AC-35792 | STL199512 | MX69 | MX-69 | BS-14153 | BCP19296 | EX-A2460 | C71033 | HY-100892 | 1005264-47-0 | s8403 | 4-...
  3. NAcM-OPT
    CAS: 2089293-61-6 Formula: C23H29Cl2N3O Molecular Weight: 434.4
    ● In Stock — US warehouse, ships to EU* Item #: N412335
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    IUPAC Name
    1-benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)urea
    SMILES
    CCCCN1CCC(CC1)N(CC2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)Cl)Cl
    InChIKey
    VPHJABWIKCBGMC-UHFFFAOYSA-N
    InChI
    1S/C23H29Cl2N3O/c1-2-3-13-27-14-11-20(12-15-27)28(17-18-7-5-4-6-8-18)23(29)26-19-9-10-21(24)22(25)16-19/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,26,29)
    Synonyms
    N-(1-butyl-4-piperidinyl)-N'-(3,4-dichlorophenyl)-N-(phenylmethyl)urea | Urea,N-​(1-​butyl-​4-​piperidinyl)​-​N'-​(3,�...
  4. NAcM-OPT
    CAS: 2089293-61-6 Formula: C23H29Cl2N3O Molecular Weight: 434.4
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N422536
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    Technical Identifiers
    IUPAC Name
    1-benzyl-1-(1-butylpiperidin-4-yl)-3-(3,4-dichlorophenyl)urea
    SMILES
    CCCCN1CCC(CC1)N(CC2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)Cl)Cl
    InChIKey
    VPHJABWIKCBGMC-UHFFFAOYSA-N
    InChI
    1S/C23H29Cl2N3O/c1-2-3-13-27-14-11-20(12-15-27)28(17-18-7-5-4-6-8-18)23(29)26-19-9-10-21(24)22(25)16-19/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,26,29)
    Synonyms
    N-(1-butyl-4-piperidinyl)-N'-(3,4-dichlorophenyl)-N-(phenylmethyl)urea | Urea,N-​(1-​butyl-​4-​piperidinyl)​-​N'-​(3,�...
  5. NSC697923
    CAS: 343351-67-7 EC Number: 803-500-4 Formula: C11H9NO5S Molecular Weight: 267.26
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N423505
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    Technical Identifiers
    IUPAC Name
    2-(4-methylphenyl)sulfonyl-5-nitrofuran
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O2)[N+](=O)[O-]
    InChIKey
    GAUHIPWCDXOLCZ-UHFFFAOYSA-N
    InChI
    1S/C11H9NO5S/c1-8-2-4-9(5-3-8)18(15,16)11-7-6-10(17-11)12(13)14/h2-7H,1H3
    Synonyms
    AM20210010 | Furan,2-[(4-methylphenyl)sulfonyl]-5-nitro- | Q27463656 | EN300-115577 | SCHEMBL15200927 | BS-16607 | HY...
  6. NSC232003
    CAS: 1905453-18-0 Formula: C6H7N3O3 Molecular Weight: 169.14
    ● In Stock — US warehouse, ships to EU* Item #: N419987
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    Technical Identifiers
    IUPAC Name
    5-[(E)-N-hydroxy-C-methylcarbonimidoyl]-1H-pyrimidine-2,4-dione
    SMILES
    CC(=NO)C1=CNC(=O)NC1=O
    InChIKey
    UDHCVAJUUVCYHW-YCRREMRBSA-N
    InChI
    1S/C6H7N3O3/c1-3(9-12)4-2-7-6(11)8-5(4)10/h2,12H,1H3,(H2,7,8,10,11)/b9-3+
  7. NVP-CGM097
    CAS: 1313363-54-0 Formula: C38H47ClN4O4 Molecular Weight: 659.26
    ● In Stock — US warehouse, ships to EU* Item #: N413861
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    Technical Identifiers
    IUPAC Name
    (1S)-1-(4-chlorophenyl)-6-methoxy-2-[4-[methyl-[[4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl]methyl]amino]phenyl]-7-propan-2-yloxy-1,4-dihydroisoquinolshow more
    SMILES
    CC(C)OC1=C(C=C2CC(=O)N(C(C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC
    InChIKey
    CLRSLRWKONPSRQ-CPOWQTMSSA-N
    InChI
    1S/C38H47ClN4O4/c1-25(2)47-35-22-33-28(20-34(35)46-5)21-36(44)43(38(33)27-8-10-29(39)11-9-27)32-16-14-30(15-17-32)41(4)23-26-6-12-31(13-7-26)42-19-18-show more
    Synonyms
    AKOS030526402 | BP-10652 | NSC783015 | NSC-783015 | SCHEMBL2391196 | CCG-270337 | Uridine pyrophosphate a-delta-galac...
  8. NVP-CGM097
    CAS: 1313363-54-0 Formula: C38H47ClN4O4 Molecular Weight: 659.26
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N421212
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    Technical Identifiers
    IUPAC Name
    (1S)-1-(4-chlorophenyl)-6-methoxy-2-[4-[methyl-[[4-(4-methyl-3-oxopiperazin-1-yl)cyclohexyl]methyl]amino]phenyl]-7-propan-2-yloxy-1,4-dihydroisoquinolshow more
    SMILES
    CC(C)OC1=C(C=C2CC(=O)N(C(C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC
    InChIKey
    CLRSLRWKONPSRQ-CPOWQTMSSA-N
    InChI
    1S/C38H47ClN4O4/c1-25(2)47-35-22-33-28(20-34(35)46-5)21-36(44)43(38(33)27-8-10-29(39)11-9-27)32-16-14-30(15-17-32)41(4)23-26-6-12-31(13-7-26)42-19-18-show more
    Synonyms
    AKOS030526402 | BP-10652 | NSC783015 | NSC-783015 | SCHEMBL2391196 | CCG-270337 | Uridine pyrophosphate a-delta-galac...
  9. Nutlin-3b
    CAS: 675576-97-3 Formula: C30H30Cl2N4O4 Molecular Weight: 581.49
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: N425398
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    Technical Identifiers
    IUPAC Name
    4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
    SMILES
    CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
    InChIKey
    BDUHCSBCVGXTJM-IZLXSDGUSA-N
    InChI
    1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,show more
    Synonyms
    (+/-)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one ...
  10. PRT 4165
    CAS: 31083-55-3 PubChem CID: 207893 Formula: C15H9NO2 Molecular Weight: 235.24
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: P423205
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    Technical Identifiers
    IUPAC Name
    2-(pyridin-3-ylmethylidene)indene-1,3-dione
    SMILES
    C1=CC=C2C(=C1)C(=O)C(=CC3=CN=CC=C3)C2=O
    InChIKey
    OMHZFEWYVFWVLI-UHFFFAOYSA-N
    InChI
    1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H
    Synonyms
    DTXSID90185032 | 2-(3-PYRIDYLMETHYLENE)-1,3-INDANDIONE | PRT4165, >=98% (HPLC) | UNII-J625FJL5DX | EX-A811 | NSC60015...
  11. PYR-41
    CAS: 418805-02-4 EC Number: 687-173-1 PubChem CID: 5335621 Formula: C17H13N3O7 Molecular Weight: 371.3
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: P423893
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    Technical Identifiers
    IUPAC Name
    ethyl 4-[(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl]benzoate
    SMILES
    CCOC(=O)C1=CC=C(C=C1)N2C(=O)C(=CC3=CC=C(O3)[N+](=O)[O-])C(=O)N2
    InChIKey
    ARGIPZKQJGFSGQ-LCYFTJDESA-N
    InChI
    1S/C17H13N3O7/c1-2-26-17(23)10-3-5-11(6-4-10)19-16(22)13(15(21)18-19)9-12-7-8-14(27-12)20(24)25/h3-9H,2H2,1H3,(H,18,21)/b13-9-
    Synonyms
    4-[4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester | ethyl 4-(4-((5-nitrofuran-2...
  12. RG7388, Tumour suppressor p53/oncoprotein Mdm2 inhibitor
    CAS: 1229705-06-9 PubChem CID: 53358942 Formula: C31H29Cl2F2N3O4 Molecular Weight: 616.48
    ● In Stock — US warehouse, ships to EU* Item #: R125598
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    Technical Identifiers
    IUPAC Name
    4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoicshow more
    SMILES
    CC(C)(C)CC1C(C(C(N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F
    InChIKey
    TVTXCJFHQKSQQM-LJQIRTBHSA-N
    InChI
    1S/C31H29Cl2F2N3O4/c1-30(2,3)14-24-31(15-36,19-10-9-17(32)13-21(19)34)25(18-6-5-7-20(33)26(18)35)27(38-24)28(39)37-22-11-8-16(29(40)41)12-23(22)42-4/hshow more
    Synonyms
    TVTXCJFHQKSQQM-LJQIRTBHSA-N | EN300-26181975 | RO5503781 | BP-25380 | 4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-...
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Frequently Asked Questions

What can I find under E1/E2/E3 Enzyme?
This listing collects compounds associated with E1/E2/E3 Enzyme within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for E1/E2/E3 Enzyme?
Consider the reported potency of each E1/E2/E3 Enzyme compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for E1/E2/E3 Enzyme compounds?
Each E1/E2/E3 Enzyme product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search E1/E2/E3 Enzyme compounds by activity or structure?
Yes. Filter the E1/E2/E3 Enzyme listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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