Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- Astaxanthin, Antioxidant, anti-inflammatory and antiapoptotic activities≥98%(HPLC) mixture of cis and trans● In Stock — US warehouse, ships to EU* Item #: A114383View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1=C(C(CC(C1=O)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(C(=O)C(CC2(C)C)O)C)C)C
- InChIKey
- MQZIGYBFDRPAKN-UWFIBFSHSA-N
- InChI
- show more
- Synonyms
- DTXSID00893777 | Natupink | UNII-8XPW32PR7I | .beta.-Carotene-4,4'-dione, 3,3'-dihydroxy-, all-trans- | BCP05821 | CH...
- SD 1008◐ .Made to order · 8–12 wks Item #: S288784View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- dimethyl (1R,5R,6R,7S)-8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylate
- SMILES
- COC(=O)C1C2C=CC(=O)C(C1C(=O)OC)N2CC3=CC=CC=C3
- InChIKey
- PYZQFEIRZQYUJQ-MIGQKNRLSA-N
- InChI
- 1S/C18H19NO5/c1-23-17(21)14-12-8-9-13(20)16(15(14)18(22)24-2)19(12)10-11-6-4-3-5-7-11/h3-9,12,14-16H,10H2,1-2H3/t12-,14-,15-,16+/m1/s1
- Synonyms
- rel-6,7-Dimethyl (1R,5R,6R,7S)-4-oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylate | HY-107595 | (1...
- AG 825CAS: 149092-50-2 Formula: C19H15N3O3S2 Molecular Weight: 397.47◐ .Made to order · 8–12 wks Item #: A275317View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-[3-(1,3-benzothiazol-2-ylsulfanylmethyl)-4-hydroxy-5-methoxyphenyl]-2-cyanoprop-2-enamide
- SMILES
- COC1=CC(=CC(=C1O)CSC2=NC3=CC=CC=C3S2)C=C(C#N)C(=O)N
- InChIKey
- KXDONFLNGBQLTN-WUXMJOGZSA-N
- InChI
- 1S/C19H15N3O3S2/c1-25-15-8-11(6-12(9-20)18(21)24)7-13(17(15)23)10-26-19-22-14-4-2-3-5-16(14)27-19/h2-8,23H,10H2,1H3,(H2,21,24)/b12-6+
- Synonyms
- (E)-3-(3-((benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide | SR-01000597586 | HMS1362L0...
- AG 99● In Stock — US warehouse, ships to EU* Item #: A286649View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
- SMILES
- C1=CC(=C(C=C1C=C(C#N)C(=O)N)O)O
- InChIKey
- USOXQZNJFMKTKJ-XVNBXDOJSA-N
- InChI
- 1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
- Synonyms
- SCHEMBL242896 | BiomolKI2_000023 | R110LV8L02 | XEA52085 | Tyrphostin A46 | BRD-K60184833-001-03-1 | EC-000.2088 | ty...
- BMS 911543, Tyrosine-protein kinase JAK2 inhibitorCAS: 1271022-90-2 Formula: C23H28N8O Molecular Weight: 432.53Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: B345013View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamide
- SMILES
- CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6
- InChIKey
- JCINBYQJBYJGDM-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,...
- PD 174265, Inhibitor of epidermal growth factor receptorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P276170View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-(3-bromoanilino)quinazolin-6-yl]propanamide
- SMILES
- CCC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
- InChIKey
- WUPUZEMRHDROEO-UHFFFAOYSA-N
- InChI
- 1S/C17H15BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h3-10H,2H2,1H3,(H,21,23)(H,19,20,22)
- Synonyms
- N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide | PD174265 | PD-174265
- PKI 166 hydrochloride● In Stock — US warehouse, ships to EU* Item #: P287660View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[[(1R)-1-phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol;hydrochloride
- SMILES
- CC(C1=CC=CC=C1)NC2=NC=NC3=C2C=C(N3)C4=CC=C(C=C4)O.Cl
- InChIKey
- ZPTWAAIZEGWMGX-BTQNPOSSSA-N
- InChI
- 1S/C20H18N4O.ClH/c1-13(14-5-3-2-4-6-14)23-19-17-11-18(24-20(17)22-12-21-19)15-7-9-16(25)10-8-15;/h2-13,25H,1H3,(H2,21,22,23,24);1H/t13-;/m1./s1
- Synonyms
- 4-[4-[[(1R)-1-Phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol hydrochloride
- (3R,4S)-TofacitinibSolid ≥98%● In Stock — US warehouse, ships to EU* Item #: T126415View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
- SMILES
- CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
- InChIKey
- UJLAWZDWDVHWOW-AAEUAGOBSA-N
- InChI
- 1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m0/s1
- Synonyms
- UNII-B64WR5WNB7 | D86134 | (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)-beta-oxo-1-piperidineprop...
- STS-E412◐ .Made to order · 8–12 wks Item #: S174607View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[2-(4-chlorophenoxy)ethoxy]-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine
- SMILES
- CC1=CC(=NC2=NC(=NN12)OCCOC3=CC=C(C=C3)Cl)C
- InChIKey
- XQFMOBKQELKMKF-UHFFFAOYSA-N
- InChI
- 1S/C15H15ClN4O2/c1-10-9-11(2)20-14(17-10)18-15(19-20)22-8-7-21-13-5-3-12(16)4-6-13/h3-6,9H,7-8H2,1-2H3
- 5,15-Diphenylporphyrin◐ .Made to order · 8–12 wks Item #: D123123View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 10,20-diphenyl-21,22-dihydroporphyrin
- SMILES
- C1=CC=C(C=C1)C2=C3C=CC(=CC4=CC=C(N4)C(=C5C=CC(=N5)C=C6C=CC2=N6)C7=CC=CC=C7)N3
- InChIKey
- QIBKIAFNCVIIMG-UHFFFAOYSA-N
- InChI
- 1S/C32H22N4/c1-3-7-21(8-4-1)31-27-15-11-23(33-27)19-25-13-17-29(35-25)32(22-9-5-2-6-10-22)30-18-14-26(36-30)20-24-12-16-28(31)34-24/h1-20,33,35H
- Synonyms
- BCP18710 | FT-0682574 | SCHEMBL2563180 | D2860 | 21H,23H-Porphine, 5,15-diphenyl- | AKOS025394541 | Stat3 Inhibitor V...
- LFM-A13, Inhibitor of Bruton tyrosine kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: L275321View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
- SMILES
- CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O
- InChIKey
- UVSVTDVJQAJIFG-VURMDHGXSA-N
- InChI
- 1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-
- Synonyms
- CCG-100654 | NCGC00025100-02 | Lopac0_000650 | a-Cyano-b-hydroxy-b-methyl-N-(2,5-dibromophenyl)propenamide | BDBM5055...
- (3S,4R)-TofacitinibSolid ≥96%● In Stock — US warehouse, ships to EU* Item #: T127249View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(3S,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
- SMILES
- CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
- InChIKey
- UJLAWZDWDVHWOW-DGCLKSJQSA-N
- InChI
- 1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m1/s1
- Synonyms
- 1-PIPERIDINEPROPANENITRILE, 4-METHYL-3-(METHYL-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YLAMINO)-.BETA.-OXO-, (3S,4R)- | 1-Piperi...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].