JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

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  1. Panaxadiol
    CAS: 19666-76-3 Formula: C30H52O3 Molecular Weight: 460.7
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: P110219
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    IUPAC Name
    (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[ashow more
    SMILES
    CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C
    InChIKey
    PVLHOJXLNBFHDX-XHJPDDKBSA-N
    InChI
    1S/C30H52O3/c1-25(2)13-9-14-30(8,33-25)19-10-16-29(7)24(19)20(31)18-22-27(5)15-12-23(32)26(3,4)21(27)11-17-28(22,29)6/h19-24,31-32H,9-18H2,1-8H3/t19-,show more
    Synonyms
    20(R)-Panaxadiol | (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5...
  2. Cardamonin
    CAS: 18956-16-6 Formula: C16H14O4 Molecular Weight: 270.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: D347756
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    IUPAC Name
    (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
    SMILES
    COC1=CC(=CC(=C1C(=O)C=CC2=CC=CC=C2)O)O
    InChIKey
    NYSZJNUIVUBQMM-BQYQJAHWSA-N
    InChI
    1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+
    Synonyms
    (E)-Cardamomin; (E)-Alpinetin chalcone | 2',4'-dihydroxy-6'-methoxychalcone | Cardamonin | 2-Propen-1-one, 1-(2,4-dih...
  3. N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine
    CAS: 916603-07-1 Formula: C17H16FN5 Molecular Weight: 309.34
    ● In Stock — US warehouse, ships to EU* Item #: N351395
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    IUPAC Name
    2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine
    SMILES
    C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN
    InChIKey
    UKOHFWNBTUJMMN-UHFFFAOYSA-N
    InChI
    1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)
    Synonyms
    HY-111138 | N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine | N2-[4-(Aminomethyl)phenyl]-5-fluoro...
  4. BPIQ-I, Inhibitor of epidermal growth factor receptor
    CAS: 174709-30-9 Formula: C16H12BrN5 Molecular Weight: 354.20
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: B330624
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    IUPAC Name
    N-(3-bromophenyl)-3-methylimidazo[4,5-g]quinazolin-8-amine
    SMILES
    CN1C=NC2=C1C=C3C(=C2)C(=NC=N3)NC4=CC(=CC=C4)Br
    InChIKey
    YAMAGACQNDAKFB-UHFFFAOYSA-N
    InChI
    1S/C16H12BrN5/c1-22-9-20-14-6-12-13(7-15(14)22)18-8-19-16(12)21-11-4-2-3-10(17)5-11/h2-9H,1H3,(H,18,19,21)
    Synonyms
    3H-Imidazo[4,5-g]quinazolin-8-amine, N-(3-bromophenyl)-3-methyl- | BRD-K72211743-001-01-1 | DTXSID60274366 | SCHEMBL1...
  5. 2-Hydroxycinnamaldehyde
    CAS: 3541-42-2 EC Number: 680-016-8 Formula: C9H8O2 Molecular Weight: 148.16
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: H157419
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    IUPAC Name
    (E)-3-(2-hydroxyphenyl)prop-2-enal
    SMILES
    C1=CC=C(C(=C1)C=CC=O)O
    InChIKey
    BSDNZCQPDVTDET-HWKANZROSA-N
    InChI
    1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+
    Synonyms
    SCHEMBL197452 | o-Hydroxy-trans-cinnamaldehyde | 2-Propenal, 3-(2-hydroxyphenyl)-, (2E)- | 7U1EE4V452 | NSC 114588 | ...
  6. AC-430
    CAS: 1359828-49-1 Formula: C19H17BrFN5O Molecular Weight: 430.274
    ◐ .Made to order · 8–12 wks Item #: A173557
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    IUPAC Name
    (4-fluorophenyl)-[4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]methanol;hydrobromide
    SMILES
    CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C(C4=CC=C(C=C4)F)O.Br
    InChIKey
    OXLABSVIPVOENF-UHFFFAOYSA-N
    InChI
    1S/C19H16FN5O.BrH/c1-11-10-16(25-24-11)22-18-14-4-2-3-5-15(14)21-19(23-18)17(26)12-6-8-13(20)9-7-12;/h2-10,17,26H,1H3,(H2,21,22,23,24,25);1H
  7. Niclosamide, Activator of K Na1.1
    CAS: 50-65-7 EC Number: 200-056-8 Formula: C13H8Cl2N2O4 Molecular Weight: 327.12
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● In Stock — US warehouse, ships to EU* Item #: N114456
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    IUPAC Name
    5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
    SMILES
    C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
    InChIKey
    RJMUSRYZPJIFPJ-UHFFFAOYSA-N
    InChI
    1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
    Synonyms
    NCGC00015735-07 | SCHEMBL67182 | Spectrum5_001083 | 2',5-Dichloro-4'-nitrosalicylanilide | CHEBI:7553 | BAY-2353 | Ni...
  8. 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
    CAS: 5334-30-5 EC Number: 808-056-5 Formula: C11H9N5 Molecular Weight: 211.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: A151535
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    IUPAC Name
    1-phenylpyrazolo[3,4-d]pyrimidin-4-amine
    SMILES
    C1=CC=C(C=C1)N2C3=NC=NC(=C3C=N2)N
    InChIKey
    KKDPIZPUTYIBFX-UHFFFAOYSA-N
    InChI
    1S/C11H9N5/c12-10-9-6-15-16(11(9)14-7-13-10)8-4-2-1-3-5-8/h1-7H,(H2,12,13,14)
    Synonyms
    ES-0020 | CHEBI:92303 | PP 3 | MLS000054252 | SCHEMBL2278510 | SBB028425 | cid_4879 | HMS3229K03 | SMR000065878 | STL...
  9. khellin
    CAS: 82-02-0 EC Number: 201-392-8 Formula: C14H12O5 Molecular Weight: 260.25
    ● In Stock — US warehouse, ships to EU* Item #: K134745
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    IUPAC Name
    4,9-dimethoxy-7-methylfuro[3,2-g]chromen-5-one
    SMILES
    CC1=CC(=O)C2=C(C3=C(C(=C2O1)OC)OC=C3)OC
    InChIKey
    HSMPDPBYAYSOBC-UHFFFAOYSA-N
    InChI
    1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3
    Synonyms
    Coronin | Kellina | Kelourin | Opera_ID_372 | Visnagalin | 4,8-dioxabenz-[f]indene | DTXCID7025267 | kelina | Viscard...
  10. Sulforaphene
    CAS: 592-95-0 EC Number: 889-720-1 PubChem CID: 6433206 Formula: C6H9NOS2 Molecular Weight: 175.27
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S276444
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    IUPAC Name
    (E)-4-isothiocyanato-1-methylsulfinylbut-1-ene
    SMILES
    CS(=O)C=CCCN=C=S
    InChIKey
    QKGJFQMGPDVOQE-HWKANZROSA-N
    InChI
    1S/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3/b5-3+
    Synonyms
    Sulforaphen | 4-Isothiocyanato-1-(methylsulfinyl)-1-butene | ISOTHIOCYANIC ACID, 4-(METHYLSULFINYL)-3-BUTENYL ESTER |...
  11. (R)-2-Amino-3-(2-propynylthio)propanoic acid
    CAS: 3262-64-4 EC Number: 889-797-1 PubChem CID: 22789047 Formula: C6H9NO2S Molecular Weight: 159.2
    ● In Stock — US warehouse, ships to EU* Item #: R183709
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    IUPAC Name
    (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid
    SMILES
    C#CCSCC(C(=O)O)N
    InChIKey
    JAKVEOCMEMGHGB-YFKPBYRVSA-N
    InChI
    1S/C6H9NO2S/c1-2-3-10-4-5(7)6(8)9/h1,5H,3-4,7H2,(H,8,9)/t5-/m0/s1
    Synonyms
    DTXSID20628366 | AS-75762 | s-propargyl-cysteine | MFCD06809960 | J-502176 | (2R)-2-amino-3-prop-2-ynylsulfanylpropan...
  12. 1-(2-Bromoisovaleryl)urea
    CAS: 496-67-3 EC Number: 207-825-7 Formula: C6H11BrN2O2 Molecular Weight: 223.07
    Solid ≥98%(T)
    ● In Stock — Germany Item #: B152707
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    IUPAC Name
    2-bromo-N-carbamoyl-3-methylbutanamide
    SMILES
    CC(C)C(C(=O)NC(=O)N)Br
    InChIKey
    CMCCHHWTTBEZNM-UHFFFAOYSA-N
    InChI
    1S/C6H11BrN2O2/c1-3(2)4(7)5(10)9-6(8)11/h3-4H,1-2H3,(H3,8,9,10,11)
    Synonyms
    BROMISOVAL [WHO-DD] | Bromisoval [INN] | Bromovaluree | GS-3579 | AB01316119-02 | Bromcarbamide | Bromovalerylurea (J...
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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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