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JAK/STAT Signaling

Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

1,726 products
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EGFR

852

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JAK

448

Explore JAK →

Pim

83

Explore Pim →

STAT

418

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Showing 565-576 of 1,726

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  3. Momelotinib sulfate
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    Momelotinib sulfate
    CAS: 1056636-06-6 PubChem CID: 66576992 Formula: C23H26N6O10S2 Molecular Weight: 610.62
    ◐ .Made to order · 8–12 wks Item #: M647163
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide;sulfuric acid
    SMILES
    C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N.OS(=O)(=O)O.OS(=O)(=O)O
    InChIKey
    XJGPMRGWDSQVTN-UHFFFAOYSA-N
    InChI
    1S/C23H22N6O2.2H2O4S/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29;2*1-5(2,3)4/h1-9,11H,12-16H2,(H,show more
    Synonyms
    A922136 | BENZAMIDE,N-(CYANOMETHYL)-4-[2-[[4-(4-MORPHOLINYL)PHENYL]AMINO]-4-PYRIMIDINYL]-,SULFATE (1:2) | BENZAMIDE, ...
  4. HER2/neu (654-662) GP2
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    HER2/neu (654-662) GP2
    CAS: 160790-21-6 PubChem CID: 448183 Formula: C42H77N9O11 Molecular Weight: 884.11
    ≥98%
    ◐ .Made to order · 8–12 wks Item #: H647427
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    Technical Identifiers
    IUPAC Name
    (2S)-2-[[(2S,3S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-hydroxyprshow more
    SMILES
    CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)O)N
    InChIKey
    XQIXDDUJIUUELO-JZOOTMHBSA-N
    InChI
    1S/C42H77N9O11/c1-14-23(10)30(43)37(56)51-34(25(12)16-3)41(60)47-28(19-52)36(55)45-26(13)35(54)49-32(22(8)9)39(58)50-31(21(6)7)38(57)44-18-29(53)48-33show more
    Synonyms
    L-Leucine, L-isoleucyl-L-isoleucyl-L-seryl-L-alanyl-L-valyl-L-valylglycyl-L-isoleucyl- | GP-2 | UNII-FQA52PV28G | (2S...
  8. SD-36
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    SD-36
    CAS: 2429877-44-9 PubChem CID: 156588550 Formula: C59H62F2N9O12P Molecular Weight: 1158.15
    ≥98%
    ◐ .Made to order · 8–12 wks Item #: S647571
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [4-[[[(2S)-2-[[(5S,8S,10aR)-5-[[5-(difluoromethyl)-1H-indole-2-carbonyl]amino]-3-[8-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-4-yl]oct-7-ynoyl]-6show more
    SMILES
    C1CC(N2C1CCN(CC(C2=O)NC(=O)C3=CC4=C(N3)C=CC(=C4)C(F)F)C(=O)CCCCCC#CC5=C6CN(C(=O)C6=CC=C5)C7CCC(=O)NC7=O)C(=O)NC(CCC(=O)N)C(=O)NC(C8=CC=CC=C8)C9=CC=C(Cshow more
    InChIKey
    PHBGXRGBBVWZKA-QLXWUKDQSA-N
    InChI
    1S/C59H62F2N9O12P/c60-53(61)37-18-22-43-38(30-37)31-45(63-43)55(75)65-46-33-68(51(73)15-8-3-1-2-5-10-34-13-9-14-41-42(34)32-69(58(41)78)47-25-27-50(72show more
  11. W1131
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    W1131
    CAS: 2740522-79-4 Formula: C23H19N5O4 Molecular Weight: 429.43
    ◐ .Made to order · 8–12 wks Item #: W647770
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    Pricing & Pack Sizes
    Technical Identifiers
    SMILES
    O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(C3=CN=C4C=C(C5=CCNCC5)C=CN43)C=C2
  12. Tarloxotinib bromide
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    Tarloxotinib bromide
    CAS: 1636180-98-7 PubChem CID: 51038315 Formula: C24H24Br2ClN9O3 Molecular Weight: 681.77
    ≥99%
    ◐ .Made to order · 8–12 wks Item #: T647912
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [(E)-4-[[4-(3-bromo-4-chloroanilino)pyrido[3,4-d]pyrimidin-6-yl]amino]-4-oxobut-2-enyl]-dimethyl-[(3-methyl-5-nitroimidazol-4-yl)methyl]azanium;bromidshow more
    SMILES
    CN1C=NC(=C1C[N+](C)(C)CC=CC(=O)NC2=NC=C3C(=C2)C(=NC=N3)NC4=CC(=C(C=C4)Cl)Br)[N+](=O)[O-].[Br-]
    InChIKey
    WAKIMVYUBWMMHJ-FXRZFVDSSA-N
    InChI
    1S/C24H23BrClN9O3.BrH/c1-33-14-30-24(34(37)38)20(33)12-35(2,3)8-4-5-22(36)32-21-10-16-19(11-27-21)28-13-29-23(16)31-15-6-7-18(26)17(25)9-15;/h4-7,9-11show more
    Synonyms
    Tarloxotinib bromide [INN] | UNII-3Y31FJ8K50 | AKOS040739933 | Tarloxotinib (bromide) | 1H-Imidazole-5-methanaminium,...
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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].
JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.
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